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Open Access Review

Nutritional Management for Infants and Children Pre and Post-Liver Transplant

Melissa Mortensen, Christine Lundberg, Simon Horslen
Received: December 05, 2018; Published: July 17, 2019; doi:10.21926/obm.transplant.1903073

Abstract: Background: Infants and children undergoing liver transplant require ongoing nutritional evaluation throughout the pre and post-transplant period. The pathophysiologic causes of chronic liver disease and acute liver failure are varied, and each present different and unique nutritional challenges. Me [...]

Open Access Review

Single Cell Transcriptomic Analysis of Pancreatic β Cell Development and Differentiation from Pluripotent Stem Cells

Chunhui Xie, Lillian Ye, Yeh-Chuin Poh, George Harb
Received: May 06, 2019; Published: July 17, 2019; doi:10.21926/obm.transplant.1903072

Abstract: Single cell genomics is a powerful tool to study cellular heterogeneity and discover novel cell types. Recent studies used single cell RNA sequencing (scRNA-seq) to analyze the transcriptomes of individual pancreatic islet cells. Islets are a complex mixture of endocrine cells and therefore represen [...]

Open Access Review

Insights from Yeast on Oxidative Stress in Alzheimer’s Disease, Focusing on Ahp1p/Prx5

Ian Macreadie, Sudip Dhakal
Received: May 05, 2019; Published: July 17, 2019; doi:10.21926/obm.geriatr.1903064

Abstract: The yeast, Saccharomyces cerevisiae, the model eukaryote, has provided many insights into molecular and cellular biology, as well as insights into many human diseases. In this paper we present some insights on how yeast studies are contributing to knowledge about the role of oxidative damage to cel [...]

Open Access Original Research

Melatonin Aggravated Oxaliplatin-Mimicking Sinusoidal Obstruction Syndrome: Role of Platelet Aggregation and Oxidative Stress

Srinivasan Periasamy, Se-Ping Chien, Bing-Fang Lee, Dur-Zong Hsu, Ming-Yie Liu 
Received: March 31, 2019; Published: July 17, 2019; doi:10.21926/obm.neurobiol.1903033

Abstract: (1) Background: Sinusoidal obstruction syndrome is a liver injury induced either by accidental ingestion of pyrrolizidine alkaloid monocrotaline or by chemotherapeutic drug oxaliplatin used for the treatment of colorectal cancer. Sinusoidal obstruction syndrome is characterized by rounding and swell [...]

Open Access Review

Curing Alzheimer’s Disease: Myriad Causes and Myriad Cures Await

Mario D. Garrett
Received: June 12, 2019; Published: July 16, 2019; doi:10.21926/obm.geriatr.1903063

Abstract: Simplifying the cause of Alzheimer’s disease has lulled the public into believing that the search for a cure is within reach. The disease has captured the attention of researchers worldwide, catapulting the disease as the third most funded research interest (after cancer and HIV). But after a centur [...]

Open Access Review

Therapeutic Strategies and Current Management for Hepatic Encephalopathy in Liver Cirrhosis

Kazuyuki Suzuki, Akinobu Kato, Yasuhiro Takikawa
Received: February 04, 2019; Published: July 16, 2019; doi:10.21926/obm.hg.1903027

Abstract: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome showing a wide spectrum and one of the serious complications seen in patients with acute and chronic liver disease or spontaneous portal-systemic shunting. Recently, HE has been classified into two categories: covert HE, which involves minim [...]

Open Access Communication

Photobiomodulation Therapy (PBMT) as a Complementary Medicine for Women to Adjust Their Autonomic Nervous Systems and Induce Specific Brain Waves - A Case Report

Jih-Huah Wu
Received: March 04, 2019; Published: July 15, 2019; doi:10.21926/obm.icm.1903046

Abstract: Sleep is very important to maintain the health of physiology and psychology, especially for women. Many studies proved the symptoms of sleep disturbance can cause inflammation, coagulation, insulin resistance and psychosocial distress in women than in men. A lot of medications were used to treat sle [...]

Open Access Review

Role of Artificial Intelligence (AI) Art in Care of Ageing Society: Focus on Dementia

Tracy Harwood, John Maltby, Elizabeta B. Mukaetova-Ladinska
Received: March 28, 2019; Published: July 15, 2019; doi:10.21926/obm.geriatr.1903062

Abstract: Background: Art enhances both physical and mental health wellbeing. The health benefits include reduction in blood pressure, heart rate, pain perception and briefer inpatient stays, as well as improvement of communication skills and self-esteem. In addition to these, people living with dementia bene [...]

Open Access Review

Breath Practices for Survivor and Caregiver Stress, Depression, and Post-traumatic Stress Disorder: Connection, Co-regulation, Compassion

Patricia L. Gerbarg, Richard P. Brown, Chris C. Streeter, Martin Katzman, Monica Vermani   
Received: April 10, 2019; Published: July 12, 2019; doi:10.21926/obm.icm.1903045

Abstract: Does compassion itself benefit the healing process or does the activation of neurophysiological processes, from which the experience of compassion arises, trigger a cascade of physical and psychological changes that support health and well-being? Exploration of the neurological substrates of compass [...]

Open Access Review

Review of Current Evidence in Acute Pancreatitis

Samantha Varley, Kirsten Rossi, Meghan Murray, Alissa Nichole
Received: May 17, 2019; Published: July 12, 2019; doi:10.21926/obm.hg.1903026

Abstract: Acute pancreatitis (AP) is an inflammatory condition of the pancreas and is one of the most common ailments of the gastrointestinal system that results in significant morbidity and mortality. The main etiologic causes of AP are alcohol consumption, gallstones, hypertriglyceridemia, and biliary stone [...]

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