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Open Access Review

Management of Neuropsychiatric Symptoms of Dementia: A Comprehensive Review of the Current Literature

Laura Suarez, Reem M.A. Shafi, Maria I. Lapid
Received: May 14, 2019; Published: September 16, 2019; doi:10.21926/obm.geriatr.1903074

Abstract: Purpose of Review: Dementia is a progressive and debilitating condition that affects millions of patients in the United States with an enormous impact on healthcare costs, caregivers, and society. Patients with dementia often experience dementia-related neuropsychiatric disturbances, commonly known [...]

Open Access Review

Facilitation of Social Support through Negative Allosteric Modulation of α5-Associated GABAA Receptors: A Novel Mechanism for the Treatment of Depression, Agitation, and Aggression in the Elderly

Jeffrey M. Witkin, Lalit K. Golani, Rok Cerne, Md. Toufiqur Rahman, Guanguan Li, Michael M. Poe, James M. Cook, Jodi L. Smith
Received: May 05, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903073

Abstract: Major depressive disorder is a highly-prevalent and debilitating disorder in the aged population. Recent and accumulating clinical evidence suggests a key role for social support in helping to mitigate depression. Preclinical data are reviewed that indicate that selective negative allosteric modul [...]

Open Access Original Research

Wisdom of the Elders: Narratives Enhancing Trainees’ Attitudes Towards Aging

James S. Powers, Destiny O. Birdsong, Kemberlee R. Bonnet, Neena R. Kapoor, Jamaria J. Southward, Ifeoma Nwankwo, David G. Schlundt
Received: April 25, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903072

Abstract: Background: Narratives encompass written reflection experiences and hold the potential to display valuable insights into trainees’ thinking. We analyzed narratives from graduate students trained in aging themes, who then interviewed older hospitalized adults (senior partners) about their life exper [...]

Open Access Original Research

Atrial Fibrillation, Anticoagulation, and Major Bleeding Episodes in Geriatric Patients at the Risk of Falling

Lennaert Zwart, Tjeerd Germans, Suat Simsek, Jaap Ruiter, René Jansen
Received: May 22, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903071

Abstract: Background: Geriatric patients are at risk for atrial fibrillation (AF), stroke, and the risk of anticoagulation (OAC) related bleeding is presumed to be higher. Detailed knowledge about the prevalence of AF and bleeding pattern in this population is scarce. This study sought to assess the prevalenc [...]

Open Access Review

Shedding Light on Manic Syndromes and Dementia

Gabriele Cipriani, Sabrina Danti, Cecilia Carlesi, Claudio Lucetti, Angelo Nuti, Mario Di Fiorino
Received: March 27, 2019; Published: August 16, 2019; doi:10.21926/obm.geriatr.1903070

Abstract: Background. Mania in older adults is associated with a high rate of medical and neurological disease. Objective. The goal of this review is to describe the phenomenon of manic episodes in patients suffering from dementia. Methods. Medline and Google Scholar searches were conducted for relevant artic [...]

Open Access Original Research

Intranasal Insulin in Alzheimer’s Disease: A Pragmatic Account

Sara Schatz, Melvin Gonzalez Rivera
Received: March 15, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903069

Abstract: Pragmatic competence includes the capacity to express illocutionary force and successfully achieve perlocutionary effects, in order to guarantee fully functional communication exchanges. Improved pragmatic competence in patients has been found in patients with Mild Cognitive Impairment (MCI) and ear [...]

Open Access Review

The Value Given and Presupposed in Person-Centred Dementia Care

Stephen Ames
Received: April 08, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903068

Abstract: Thirty years ago, Tom Kitwood proposed a change in the care of people with dementia, from ‘warehousing’ to ‘person-centred care’. The change had noticeable benefits for those with dementia. Kitwood set out his presuppositions for this change. For example, Kitwood understood personhood as the stand [...]

Open Access Original Research

Differential Effects of Social Network on Health in Later Life and the Moderating Role of Depression

Shira Peleg, Howard Litwin
Received: March 23, 2019; Published: August 12, 2019; doi:10.21926/obm.geriatr.1903067

Abstract: Background: We studied the differential effects of social network characteristics on limitations with activities (LWA) and quality of life (QOL) among older adults, and the moderating role of depression. Methods: Data from two consecutive waves of the Survey of Health, Aging and Retirement in Europe [...]

Open Access Case Report

Personalised Medicine for Dementia: Collaborative Research of Multimodal Non-pharmacological Treatment with the UK National Health Service (NHS)

Garuth Chalfont, Jane Simpson, Sarah Davies, David Morris, Ruth Wilde, Leigh Willoughby, Christine Milligan
Received: April 08, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903066

Abstract: The dominant narrative around dementia argues that progression cannot be halted or reversed. However, evidence on multimodal non-pharmacological treatments formulated around a ‘personalised medicine’ approach challenges this view. This paper reviews the current evidence for dementia prevention utili [...]

Open Access Review

A Model for Understanding Hispanic/Latino Family Caregiving for Older Adults

Hsueh-Fen S. Kao, Maria A. Amaya
Received: May 19, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903065

Abstract: Background: In 2016, Hispanic/Latino (H/L) Americans made up 8% of the older population (≥65) and 22.9% of the oldest population (≥85) in the United States. It is projected that the older H/L population will grow to 21% by 2060. Currently the older H/L population depends primarily on their families [...]

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