Table of Content

Open Access Review

Endoscopic Therapy for Recurrent Acute Pancreatitis

Pier Alberto Testoni, Sabrina Testoni
Received: October 17, 2019; Published: December 23, 2019; doi:10.21926/obm.hg.1904042

Abstract: Recurrent acute pancreatitis (RAP) is a clinical entity characterized by episodes of acute pancreatitis which occurs on more than one occasion. Recurrence of pancreatitis generally occurs in a setting of a normal anatomical and functional gland, however, a chronic disease at early stage may be found [...]

7 143

Open Access Original Research

The Daclatasvir/Asunaprevir/Beclabuvir Combination Therapy for Chronic Hepatitis C Patients Experiencing Failure of IFN-Free DAA-Based Therapies

Ken Sato, Atsushi Naganuma, Shuichi Saito, Yuichi Yamazaki, Takeshi Kobayashi, Hiroki Tojima, Norio Horiguchi, Satoru Kakizaki, Toshio Uraoka, Hiroshi Ohnishi, Hiroaki Okamoto
Received: September 29, 2019; Published: December 17, 2019; doi:10.21926/obm.hg.1904041

Abstract: Background: Daclatasvir/asunaprevir/beclabuvir (DCV/ASV/BCV) combination therapy had been available for the treatment of chronic hepatitis C patients with genotype 1 (CHG1) in Japan. Our aim was to report the efficacy and safety of DCV/ASV/BCV in patients experiencing treatment failure with interfer [...]

22 188

Open Access Case Report

Hypereosinophilia with Gastrointestinal Involvement: A Case Report

Mauro Turrin, Barbara Mariotti, Isabella Schiavon, Serena Battista
Received: September 29, 2019; Published: November 22, 2019; doi:10.21926/obm.hg.1904040

Abstract: Hypereosinophilic syndrome is currently defined by an absolute blood eosinophil count of more of 1500 cell per μL for more than 1 month and by multiorgan system infiltration. Eosinophilic colitis is an exceptionally rare inflammatory condition in which eosinophils infiltrate the colonic gut. It repr [...]

45 233

Open Access Review

Platelet Function in Experimental Models of Liver Cirrhosis

Paola Romecín, Joaquín García-Estañ, Noemí M. Atucha
Received: May 15, 2019; Published: November 01, 2019; doi:10.21926/obm.hg.1904039

Abstract: (1) Background: Platelet function is commonly altered in liver cirrhosis. In experimenta models of liver cirrhosis we have analyzed the mechanisms of this defective function. (2) Methods: Experiments were performed in a model of liver cirrhosis by bile duct-ligation in washed platelets by means of f [...]

38 306

Open Access Case Report

Primary Pancreatic-Type Acinar Cell Carcinoma of Jejunum Arising from Ectopic Pancreas with Synchronous Metastasis to Left Adrenal Gland

Oliver H. Wang, Priya R. Bhosale, Jeannelyn S. Estrella
Received: July 08, 2019; Published: October 28, 2019; doi:10.21926/obm.hg.1904038

Abstract: Background: Pure pancreatic-type ACC outside the pancreas is extremely rare. Methods: We presented a very rare case of primary ACC of the pancreatic-type involving jejunum with a synchronous metastasis to left adrenal gland arising in well-developed ectopic pancreas which had fully developed pancre [...]

35 237

Open Access Case Report

Partial Response of Alopecia Areata to Helicobacter Pylori Eradication and Treatment with Low-Dose Naltrexone

Laura Alonso Canal, María José Quiles Blanco, David Jiménez Leiva, María José González Iglesias
Received: June 26, 2019; Published: September 30, 2019; doi:10.21926/obm.hg.1903037

Abstract: Alopecia areata is an autoimmune disease of unknown origin. It has been proposed that it is a multifactorial disease with genetic, immunological, infectious, circulatory, and psychogenic factors being involved in its etiopathogenesis. Its association with other autoimmune diseases is frequent. The i [...]

32 317

Open Access Perspective

Missing the Target to Treat in Crohn’s Disease

Herbert Van Kruiningen
Received: April 05, 2019; Published: September 30, 2019; doi:10.21926/obm.hg.1903036

43 375

Open Access Case Report

Secondary Acute Pancreatitis Associated with Paracetamol and Codeine Administration after Dental Treatment: Literature Analysis and Clinical Case Study

Alessandro Luigi Rossi, Vincenzo Capilupi, David Palombo, Luigi Tagliatesta, Tecla Terenzio, Marco Vitali, Matteo Chiapasco
Received: April 29, 2019; Published: August 30, 2019; doi:10.21926/obm.hg.1903035

Abstract: OBJECTIVES To review current literature analysing possible secondary complications in response to the administration of paracetamol and codeine as analgesics in the dental field. To discuss a case of secondary acute pancreatitis triggered by the administration of both active ingredients. MATERIALS A [...]

46 444

Open Access Review

Rare Causes of Acute Pancreatitis: Drugs, Eosinophilia, and Autoimmunity

Mauro Turrin
Received: March 15, 2019; Published: August 29, 2019; doi:10.21926/obm.hg.1903034

Abstract: Background: Among the rarest causes of acute pancreatitis, in addition to the drugs (DIAP), there are eosinophilic pancreatitis (EP) and autoimmune pancreatitis (AIP). Methods: we have researched on PUBMED the descriptions of clinical cases of eosinophilic pancreatitis appeared from 1990 to February [...]

40 473

Open Access Review

Advanced Endoscopic Techniques in the Evaluation and Treatment of Fibrostenotic Crohn's Disease

Alina Wong, Scott D Lee
Received: May 09, 2019; Published: August 16, 2019; doi:10.21926/obm.hg.1903033

Abstract: Crohn’s disease is characterized by chronic intestinal inflammation that can result in significant morbidity and loss of intestinal function over time. Many novel treatments for Crohn’s disease are being developed, but a significant portion of patients still requires surgical therapy for structuring [...]

42 461