Table of Content

Open Access Review

Herb-Drug Interactions in Oncology: A Clinical Up-Date

Francesco Sivelli, Elio Rossi, Sonia Baccetti, Mariella Di Stefano, Eugenia Gallo, Fabio Firenzuoli
Received: September 27, 2018; Published: October 18, 2019; doi:10.21926/obm.icm.1904060

Abstract: In this article we shortly inform about the most important mechanisms lying at the basis of herb-drug interactions (HDI). We summarized the best known and relevant ones emerging from clinical evidence. The last part is dedicated to cancer patients

Open Access Concept Paper

Admiral Nursing in Primary Care: Peri and Post-Diagnostic Support for Families Affected by Dementia within the UK Primary Care Network Model

Zena Aldridge, Karen Harrison Dening
Received: September 19, 2019; Published: October 18, 2019; doi:10.21926/obm.geriatr.1904081

Abstract: The UK population is ageing. In 2017 approximately 18% of the UK population were aged 65 years or over and projected to grow to almost 21% by 2027 according to the Office of National Statistics (ONS) (2018a). Increased age is the greatest risk factor for developing dementia (Van de Flier & Sche [...]

Open Access Review

Optimizing Phage Translation Initiation

Xuhua Xia
Received: June 9, 2019; Published: October 17, 2019; doi:10.21926/obm.genet.1904097

Abstract: Phage as an anti-bacterial agent must be efficient in killing bacteria, and consequently needs to replicate efficiently. Protein production is a limiting step in replication in almost all forms of life, including phages. Efficient protein production depends on the efficiency of translation initiatio [...]

Open Access Review

Insulin-Like Growth Factor 2 in Physiology, Cancer, and Cancer Treatment

Bas T Röttgering, Karoly Szuhai
Received: May 14, 2019; Published: October 14, 2019; doi:10.21926/obm.genet.1904096

Abstract: IGF2 is a strongly mitogenic peptide and imprinted gene primarily involved in foetal development. In the foetus, IGF2 is highly expressed and is involved with foetal growth and tissue differentiation. However, postnatally IGF2 expression decreases although its expression level is still higher in blo [...]

Open Access Original Research

Naming and Framing the Behavioural and Psychological Symptoms of Dementia (BPSD) Paradigm: Professional Stakeholder Perspectives

Emma Wolverson, Heather Birtles, Esme Moniz-Cook, Ian James, Dawn Brooker, Frances Duffy
Received: September 08, 2019; Published: October 11, 2019; doi:10.21926/obm.geriatr.1904080

Abstract: Background Behavioural and Psychological Symptoms of Dementia and Challenging Behaviour in dementia care are just two of a variety of terms for a complex paradigm that covers the most distressing and costly aspects of the condition. The terminology used to describe these aspects can influence what [...]

Open Access Original Research

Formulation-Properties of Novel Ibuprofen-Loaded Soy Protein Wound Dressings

Lia Ofek, Daniella Goder, Meital Zilberman
Received: July 31, 2019; Published: October 11, 2019; doi:10.21926/rpm.1904004

Abstract: Wound management constitutes a significant field in medical care, as millions of wounds require treatment worldwide every year. Soy protein has the advantages of being a highly biocompatible, easily processed, relatively cheap natural polymer, which can be used for wound dressing applications. In th [...]

Open Access Research Article

Does a Brief Mindfulness Training Enhance Heartfulness in Students? Results of a Pilot Study

Myriam Rudaz, Thomas Ledermann, Michael P. Twohig, Michael E. Levin
Received: May 24, 2019; Published: October 10, 2019; doi:10.21926/obm.icm.1904059

Abstract: (1) Background: There is robust evidence that mindfulness trainings enhance mindfulness as operationalized in Western psychology, but evidence about heartfulness is sparse. This study seeks to test whether a brief mindfulness training enhances heart qualities, including self-compassion, gratitude, a [...]

Open Access Perspective

Behavioral versus Biological Definitions of Dementia Symptoms: Recognizing that Worthwhile Interventions already Exist

Robert J. Brent
Received: July 31, 2019; Published: October 10, 2019; doi:10.21926/obm.geriatr.1904079

Abstract: Background: The 2018 Alzheimer’s Disease Facts and Figures special report includes two new guidelines for measuring dementia symptoms. The first requires that a biomarker (biological factor) be added to a doctor’s clinical judgment of the cause of symptoms when determining whether dementia is presen [...]

Open Access Research Article

GAPcare: The Geriatric Acute and Post-Acute Fall Prevention Intervention for Emergency Department Patients – A Qualitative Evaluation

Elizabeth M. Goldberg, Cameron J. Gettel, Kelsey Hayes, Renee R. Shield, Kate M. Guthrie
Received: August 21, 2019; Published: October 10, 2019; doi:10.21926/obm.geriatr.1904078

Abstract: Three million US emergency department (ED) visits occur for falls each year. The mortality of falls is increasing and only one fourth of older adults report their fall to their primary care provider, suggesting that valuable preventative opportunities are missed. A fall prevention intervention initi [...]

Open Access Original Research

Acute Exercise on Reversal Learning

Claire Sanderson, Paul D. Loprinzi
Received: July 15, 2019; Published: October 09, 2019; doi:10.21926/obm.neurobiol.1904043

Abstract: Objective: Reversal learning requires an individual to alter their behavior when previously learned reward-based contingencies are reversed. Reversal learning is heavily influenced by cognitive flexibility, which has been shown to be enhanced with acute exercise. However, minimal work has directly e [...]