Table of Content

Open Access Review

Sleep and Help Seeking Behaviours in Australia: A Narrative Review

Received: 22 March 2019;  Published: 27 June 2019;  doi: 10.21926/obm.neurobiol.1902029


Inadequate sleep is a largely under recognised problem in Australian communities despite researchers consistently highlighting it as a key component of health and wellbeing. Over a third of Australian adults now experience some form of inadequate sleep, which is strongly linked to a range of accompa [...]

106 1156

Open Access Case Report

Changes in SPECT Brain Imaging in Pediatric Patients with Suspected Neuroborreliosis: A Series of 6 Cases

Received: 01 April 2019;  Published: 14 May 2019;  doi: 10.21926/obm.neurobiol.1902028


Lyme disease is a disease transmitted by ticks with a broad spectrum of comorbidity associated, from purely osteoarticular to neurological, as well as great variability comorbidity depending on the age of the individual. It currently represents an epidemic recognized by the CDC and confers a very i [...]

125 1038

Open Access Review

Connections between Early-Life Neuroinflammation, Neural Stem Cells and Progenitors and Origins of Neuropsychiatric Disorders

Received: 13 February 2019;  Published: 13 May 2019;  doi: 10.21926/obm.neurobiol.1902027


A number of studies have highlighted the connection between infections during pregnancy in mothers and increased risk for neuropsychiatric disorders later in life leading to the view that maternal immune activation is a significant contributor to psychiatric illnesses. Meta-analyses have revealed a [...]

161 1102

Open Access Review

The Effects of Exercise on Long-Term Potentiation: A Candidate Mechanism of the Exercise-Memory Relationship

Received: 30 March 2019;  Published: 10 May 2019;  doi: 10.21926/obm.neurobiol.1902026


Objective: The objective of this paper was to evaluate the extent to which exercise may influence long-term potentiation (LTP), a key cellular correlate of episodic memory function. Methods: Studies were identified using electronic databases, including PubMed, PsychInfo, Sports Discus and Google Sch [...]

153 1371

Open Access Editorial

Editorial: “A New Era in Neuro-Oncology”

Received: 05 May 2019;  Published: 08 May 2019;  doi: 10.21926/obm.neurobiol.1902025

114 821

Open Access Research Article

Gluten-Free Diet for the Treatment of ADHD; Pilot Study

Received: 17 December 2018;  Published: 03 April 2019;  doi: 10.21926/obm.neurobiol.1902024


Aim: The association between Attention deficit hyperactivity disorder (ADHD) and celiac disease has already been established. Non-celiac gluten sensitivity (NCGS), as well as celiac disease, has been associated with neuro-psychiatric disorders. Our objective is to assess if a proportion of pediatric [...]

117 860

Open Access Review

Ischemic Brain Injury and Regulatory T Cells

Received: 13 January 2019;  Published: 27 March 2019;  doi: 10.21926/obm.neurobiol.1901023


Inflammation and immune responses after stroke including ischemic cerebral infarction play pivotal roles in the pathology, resolution of inflammation, and neurological recovery. Regulatory T (Treg) cells are the cells responsible for immune tolerance, usually activated by secondary lymphatic tissues [...]

132 1041

Open Access Review

Diffuse Intrinsic Pontine Glioma: Translation of Genomic Knowledge to Clinical Practice

Received: 29 November 2018;  Published: 12 March 2019;  doi: 10.21926/obm.neurobiol.1901022


Pediatric brain tumors account for approximately 25% of all cancers in children and are currently the leading cause of cancer-related deaths in the pediatric population with an estimated incidence of 5.14 cases per 100,000 persons [1]. Up to 10-15% of all pediatric brain tumors arise in the brainste [...]

113 1030

Open Access Review

Sporadic and Hereditary Hemangioblastoma: The Role of Endothelial Cells

Received: 26 November 2018;  Published: 04 March 2019;  doi: 10.21926/obm.neurobiol.1901021


Hemangioblastomas (HBs) are benign, highly vascularized tumors of the central nervous system. About 75% of HBs are sporadic, while 25% are associated with von Hippel-Lindau (VHL) disease. HBs consist of two main components, a rich capillary network composed of vascular endothelia and pericytes, with [...]

108 837

Open Access Research Article

Magnetic Resonance Imaging Approaches for Predicting the Response to Hyperoxic Radiotherapy in Glioma-Bearing Rats

Received: 11 November 2018;  Published: 30 January 2019;  doi: 10.21926/obm.neurobiol.1901020


Background: Despite the advances in multimodal therapeutic options, glioblastoma (GBM), the most frequent and aggressive of all astrocytomas, remains with a median survival of 15 months. It is reported a direct correlation between GBM hypoxia and a higher aggressiveness, poor prognosis and greater r [...]

117 1137