Table of Content

Open Access Review

Hematopoietic Stem Cell Transplantation in Refractory Celiac Disease: An Overview with Focus on Infectious Complications

Abdulbaqi Al-Toma, Harry R. Koene
Received: December 16, 2019; Published: February 18, 2020; doi:10.21926/obm.transplant.2001101

Abstract: Refractory celiac disease (RCD) is a rare condition in which a known celiac patient, usually an adult, suffers from persistence or recurrence of gluten-related symptomatology, laboratory abnormalities, and inflammatory enteropathy despite following an optimal dietary therapy with gluten-free diet (G [...]

35 393

Open Access Editorial

Transplantation of a Kidney with an Extra-Renal Organ

Steven R. Potter
Received: February 10, 2020; Published: February 13, 2020; doi:10.21926/obm.transplant.2001100

36 342

Open Access Original Research

Eplet-Based HLA Class II Matching for Transplantation: Design of a Repertoire of Interlocus Eplets Shared between HLA-DR, -DQ and -DP Alleles

Rene J. Duquesnoy, Marilyn Marrari
Received: December 13, 2019; Published: February 11, 2020; doi:10.21926/obm.transplant.2001099

Abstract: Many studies have demonstrated that HLA-DR, HLA-DQ and HLA-DP matching at the eplet level reduces allograft rejection and improves transplant outcome. Such studies have examined the eplet effect for the individual class II loci, but until now little attention has been given to so-called interlocus c [...]

123 426

Open Access Review

Utility of Fungal Cell Markers in Pediatric Bone Marrow Transplant Recipients for Screening and Diagnosis of Invasive Fungal Infections

Nour Hasan, Ankita P. Desai, Jignesh Dalal
Received: November 12, 2019; Published: February 03, 2020; doi:10.21926/obm.transplant.2001098

Abstract: Invasive fungal disease (IFD) is a significant contributor to morbidity and mortality in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT). Early detection and timely initiation of antifungal therapy is important for improved outcome, but diagnosis remains difficult, espec [...]

33 402

Open Access Editorial

Immunosuppression in Kidney Transplantation

Maurizio Salvadori, Aris Tsalouchos
Received: January 19, 2020; Published: February 03, 2020; doi:10.21926/obm.transplant.2001097

Abstract: Immunosuppressive therapy in renal transplantation is divided into two phases as induction and maintenance therapy. Induction therapy is an intense immunosuppressive therapy administered at the time of kidney transplantation to reduce the risk of acute allograft rejection. In general, induction immu [...]

37 420

Open Access Case Report

Dual Kidney Transplantation after Hypothermic Oxygenated Perfusion from Marginal Donor after Circulatory Death with Acute Kidney Injury: A Case Report

Federica Odaldi, Vanessa De Pace, Giacomo Frascaroli, Giuliana Germinario, Giorgia Comai, Francesco Vasuri, Gaetano La Manna, Matteo Ravaioli
Received: November 22, 2019; Published: February 03, 2020; doi:10.21926/obm.transplant.2001096

Abstract: Donation after circulatory death (DCD) is an increasingly used resource to alleviate chronic renal graft shortages. Organs from donors with progressively increased creatinine levels due to acute kidney injury are used, but the effects of this condition on kidney transplantation are still unclear. Ex [...]

63 401

Open Access Research Article

Long-Term Exposure to Fine Particulate Matter (PM2.5) and Cardiovascular Disease Mortality among Renal Transplant Recipients

Salem Dehom, Synnove Knutsen, David Shavlik, Khaled Bahjri, Hatem Ali, Lance Pompe, Rhonda Spencer-Hwang
Received: August 11, 2019; Published: December 17, 2019; doi:10.21926/obm.transplant.1904095

Abstract: Background: Substantial evidence has been used to establish links between air pollution and increased risks of overall health morbidity and mortality, especially for respiratory and cardiovascular diseases. However, very few investigations have explored these relationships among highly sensitive pop [...]

45 559

Open Access Review

Modelling Recurrent Primary Biliary Cholangitis and Primary Sclerosing Cholangitis as Infectious Diseases Following Liver Transplantation

Victor Dong, Aldo J. Montano-Loza, Andrew L. Mason
Received: November 19, 2019; Published: December 13, 2019; doi:10.21926/obm.transplant.1904094

Abstract: Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are idiopathic and progressive autoimmune hepatobiliary disorders that lead to liver failure and a need for liver transplantation in a proportion of individuals with poorly controlled disease. It is currently thought that an [...]

53 462

Open Access Review

Therapeutic Apheresis in Prevention and Treatment of Antibody-Mediated Rejection of Renal Allografts

Maurizio Salvadori, Aris Tsalouchos
Received: October 13, 2019; Published: December 02, 2019; doi:10.21926/obm.transplant.1904093

Abstract: Antibody-mediated rejection represents a significant barrier to favourable long-term outcomes after kidney transplantation and is the most common cause of allograft failure. Therapeutic apheresis techniques associated with other treatments, such as immunosuppressive drugs, are commonly used in the p [...]

62 512

Open Access Research Article

Incidence, Location, and Natural History of Perihepatic Fluid Collections after Orthotopic Liver Transplantation

Sumail Bhogal, Matthew Minn, Pranay Krishnan, Reena C. Jha
Received: February 18, 2019; Published: November 18, 2019; doi:10.21926/obm.transplant.1904092

Abstract: Objective: The purpose of this study was to evaluate the common locations of perihepatic fluid collections after liver transplantation, assess their complexity, and understand their natural history and clinical significance. Materials and Methods: A retrospective analysis of 189 postoperative ortho [...]

53 559