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Open Access Review

Cardiac Allograft Vasculopathy: A Review of Risk Factors and Pathogenesis

Mrudula Munagala, Anita Phancao
Received: August 31, 2017; Published: January 14, 2018; doi:10.21926/obm.transplant.1801007

Abstract: Heart transplant remains the gold standard therapy for patients with end stage heart disease and offers improved survival and quality of life. Significant progress has been achieved in improving one year mortality after heart transplantation. Nonetheless, long-term graft survival has not changed sig [...]

Open Access Editorial

The Fundamental Challenges in Organ Transplantation

Pål Dag Line
Received: December 20, 2017; Published: December 24, 2017; doi:10.21926/obm.transplant.1704006

Abstract: Organ transplantation is a unique form of therapy for organ failure. The results are overall extremely good, saving the lives of a large cohort of patients that would otherwise die or be left with reduced life expectancy and a poor quality of life. Yet, the success of transplantation creates a prob [...]

Open Access Review

Management of Cardiac Allograft Vasculopathy

Rama Bindu Manchikalapudi
Received: May 31, 2017; Published: September 29,2017; doi:10.21926/obm.transplant.1703005

Abstract: Cardiac allograft vasculopathy(CAV) is one of the leading causes of death following the first 5 years after orthotopic heart transplantation(OHT) along with late graft failure( likely secondary to undiagnosed CAV. Currently there is no single medical treatment available for this condition except m [...]

Open Access Review

Malignancy in the Lung Transplant Population

Sheri Tran, Mark M. Fuster
Received: July 16, 2017; Published: September 13,2017; doi:10.21926/obm.transplant.1703004

Abstract: The risk for developing a variety of malignancies is significantly elevated in the setting of lung transplantation. Malignancy remains among the three major causes of death in post-transplant recipients, and the relatively high risk of cancer development as well as metastatic aggression pose special [...]

Open Access Review

IVIG Replacement for Hypogammaglobulinemia in Lung Transplant Patients

In Lam, Irina Gutman, Ashley Feist, Mark Mariski
Received: March 10, 2017; Published: June 22, 2017; doi:10.21926/obm.transplant.1701003

Abstract: After lung transplant, infection is a leading contributor to morbidity and mortality, and hypogammaglobulinemia (HGG) may be an important risk factor for many of these infections.  Some reports suggest that HGG not only increases the risk of various infections, but also worsens survival.  The incide [...]

Open Access Review

Anti-HLA Antibodies in Lung Transplantation

Gerald P. Morris
Received: February 20, 2017; Published: April 11, 2017; doi:10.21926/obm.transplant.1701002
(This article belongs to the Special Issue Lung Transplant)

Abstract: (1) Background: Lung transplantation is an increasingly utilized treatment for end-stage lung disease. Scarcity of organ donors limiting transplantation underscores the importance of optimal histocompatibility testing approaches to facilitate organ allocation and avoid immunologic rejection. Signifi [...]

Open Access Editorial

OBM Transplantation—A New Hub in the Network of Transplantation Science

Pål Dag Line
Received: April 7, 2017; Published: April 11, 2017; doi:10.21926/obm.transplant.1701001

Abstract: none

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