OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.1 weeks; Submission to Acceptance: 17.0 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

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Special Issue

Epigenetics and Chromosome Biology

Submission Deadline: October 15, 2020 (Open) Submit Now

Guest Editor

Marcel Mannens, PhD

Professor, Department of Clinical Genetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands

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Research Interests: genome diagnostics; epigenetics of disease; cardiogenetics

Co-Editor

Peter Henneman, PhD

Assistant Professor, Department of Clinical Genetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands

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Research Interests: Systems biology; metabolic syndrome; diabetes; genetics; insulin resistance

About This Topic

Epigenetics is meant by the study of heritable changes in gene function without involving the changes in DNA arrangement. It mainly involves the changes in a chromosome which affects gene activity and functions, and also be used to report any heritable phenotypic change which does not derive from a modification of the genome. These changes include modifications to elements surrounding genes, such as histone proteins, or modification to the transcriptional elements that control gene expression. Unlike changes to the genes themselves, epigenetic changes are usually generation-specific. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. In other words, epigenetic changes are not usually passed from parent to child. This relatively new science has reshaped our understanding of both normal development and disease processes and is now influencing development of the next generation of therapies.

Epigenetics defined as the study of the Epigenotype, which deals with the study of the properties of the pathways and processes that link the genotype and phenotype. A large number of diseases in humans such as Cancer, metabolic syndromes and brain disorders have been related with irregularity in epigenetic processes. In this special issue, we will seek articles that reflect the research on epigenetics and chromosome. Original research reports, review articles, communications, perspectives, etc., are invited in all areas pertinent to this topic.

Planned Paper

Title: Similarities in epigenetic (DNA methylation) changes in developing mammalian retina and retinal organoids
Authors: Igor O. Nasonkin, et al

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (genetics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

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