OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes research articles, reviews, communications and technical notes, etc. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Indexing: DOAJ-Directory of Open Access Journals.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 8.5 days from acceptance to publication (median values for papers published in this journal in the first half of 2019, 1-2 days of FREE language polishing time is also included in this period).
Epigenetics and Chromosome Biology
Submission Deadline: October 15, 2020 (Open) Submit Now
Marcel Mannens, PhD
Professor, Department of Clinical Genetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Research Interests: genome diagnostics; epigenetics of disease; cardiogenetics
Peter Henneman, PhD
Assistant Professor, Department of Clinical Genetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Research Interests: Systems biology; metabolic syndrome; diabetes; genetics; insulin resistance
About This Topic
Epigenetics is meant by the study of heritable changes in gene function without involving the changes in DNA arrangement. It mainly involves the changes in a chromosome which affects gene activity and functions, and also be used to report any heritable phenotypic change which does not derive from a modification of the genome. These changes include modifications to elements surrounding genes, such as histone proteins, or modification to the transcriptional elements that control gene expression. Unlike changes to the genes themselves, epigenetic changes are usually generation-specific. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. In other words, epigenetic changes are not usually passed from parent to child. This relatively new science has reshaped our understanding of both normal development and disease processes and is now influencing development of the next generation of therapies.
Epigenetics defined as the study of the Epigenotype, which deals with the study of the properties of the pathways and processes that link the genotype and phenotype. A large number of diseases in humans such as Cancer, metabolic syndromes and brain disorders have been related with irregularity in epigenetic processes. In this special issue, we will seek articles that reflect the research on epigenetics and chromosome. Original research reports, review articles, communications, perspectives, etc., are invited in all areas pertinent to this topic.
Title: Similarities in epigenetic (DNA methylation) changes in developing mammalian retina and retinal organoids
Authors: Igor O. Nasonkin, et al
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