OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 8 days from acceptance to publication (median values for papers published in this journal in 2020, 1-2 days of FREE language polishing time is also included in this period).
Delirium in Older Adults
Submission Deadline: September 15, 2021 (Open) Submit Now
Catherine Travers, PhD
Senior Research Fellow, Dementia Collaborative Research Centre: Carers and Consumers (DCRC: CC), School of Nursing, Queensland University of Technology, Brisbane, Australia
Research Interests: Aging; dementia; geriatric cares; cognitive impairment; frailty; delirium; nursing; interventions to improve older people’s quality of life
About This Topic
Delirium is a common and serious condition amongst older people that is associated with a range of adverse consequences including falls, cognitive and functional decline and increased morbidity and mortality. While it is most often due to a medical condition (that may indicate a medical emergency requiring prompt intervention), causes are numerous and often multifactorial. It is frequently present at admission to hospital in older patients and is common following major surgery (particularly hip fracture and cardiac surgery). Yet, despite its seriousness, delirium is often under-recognized and consequently under-treated.
Although delirium can be difficult to detect, in part due to its abrupt onset, fluctuating nature and varied presentation, there is evidence that it can be prevented and appropriately managed to optimize patient outcomes. Ensuring that delirium is not overlooked with potentially fatal consequences means clinicians must be familiar with, and have a high index of suspicion for the condition in older patients.
This special issue of OBM Geriatrics aims to highlight the importance of delirium in older people and bring together the latest research about the condition in a single forum to inform researchers and clinicians alike. Submissions in relation to any aspect of delirium in older adults including its prevalence across various settings, its etiology, diagnosis, prevention and management as well as examples of effective interventions are welcome. Review articles as well as articles that provide critical new insights about the condition, are particularly welcome.
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