Table of Contents

Volume 2,Issue 2

Open Access Original Research

Haplo-Insufficiency or Knockout of the Serotonin Transporter Does not Affect Heroin Self-Administration but Decreases BDNF in the Frontal Cortex

Received: 01 February 2018;  Published: 07 June 2018;  doi: 10.21926/obm.neurobiol.1802010

Abstract

(1) Background: Drug addiction places a heavy burden on those affected by it but only a small percentage of individuals (~20%), regardless of their drug of abuse, go on to develop the compulsive behaviours that define drug addiction. Clinical studies have shown that genetic variations that reduce se [...]

Open Access Review

Temporal Lobe Epilepsy, Stroke, and Traumatic Brain Injury: Mechanisms of Hyperpolarized, Depolarized, and Flow-Through Ion Channels Utilized as Tri-Coordinate Biomarkers of Electrophysiologic Dysfunction

Received: 12 January 2018;  Published: 31 May 2018;  doi: 10.21926/obm.neurobiol.1802009

Abstract

The brain is an integrated network of multiple variables that when compromised creates a disease state. The neuropathology of temporal lobe epilepsy, stroke, and traumatic brain injury demonstrate both similarity and complexity that reflects this integrated variability; temporal lobe epilepsy with i [...]

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