Characterisation of Oxidative Stress, DNA Damage and Inflammation in a Cellular Model of Parkinson’s Disease
OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
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Oxidative Stress and Inflammatory Responses in Neurodegenerative Diseases
Submission Deadline: May 30, 2020 (Open) Submit Now
Mohammad Moshahid Khan, PhD
Assistant Professor, Departments of Neurology and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, United States
Research Interests: Neuroscience; Pharmacology; Neurodegeneration; Neuroinflammation; Parkinson’s Disease; Stroke; Alzheimer’s Disease; Multiple Sclerosis and Traumatic Brain Injury
About This Topic
Inflammation and Oxidative stress are common features of chronic neurodegenerative diseases of the central nervous system. Chronic inflammation is characterized by longstanding microglial activation followed by sustained release of inflammatory mediators, which aid in enhanced nitrosative and oxidative stress. The sustained release of inflammatory mediators propels the inflammatory cycle by increased microglial activation, promoting their proliferation and thus stimulating enhanced release of inflammatory factors. Elevated levels of several cytokines and chronic neuroinflammation have been associated with many neurodegenerative disorders of central nervous system like age-related macular degeneration, Alzheimer disease, multiple sclerosis, Parkinson’s disease, Huntington’ disease, and tauopathies. In this special issue, we aim to the introduction of the relative research the basic mechanisms of neuroinflammation and oxidative stress, the characteristics of neurodegenerative diseases, and the main immunologic responses in CNS neurodegenerative disorders. Original research reports, review articles, communications, and perspectives are welcome in all areas pertinent to the topic. All accepted papers will be published totally free of charge.
Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. Guidelines for authors and other relevant information for submission of manuscripts are available on the Instructions for Authors page. OBM Neurobiology is an international peer-reviewed Open Access monthly journal published by LIDSEN. Please visit the Instructions for Authors page before submitting a manuscript.
Neurodegenerative diseases; Inflammation; Oxidative stress; Cytokines and Inflammatory factors
Title: Correlation Between Neuroimaging and Epigenetics in Chronic Discogenic Lumbar Pain
Authors: M.Marchesini 1, N. Peroni 2, M. Allegri 3
1. Pain Medicine Unit, ICS S. Maugeri Pavia, Italy
2. Anesthesia, Intensive Care Pain Medicine Department, San Matteo Pavia, Italy
3. Pain Therapy Service, Policlinico Monza Hospital, Monza Italy
Title: Oxydative stress and low grade inflammation in electrohypersensitivity self-reporting patients
Authors: Philippe Irigaray, Dominique Belpomme
Affiliation: Association for Research Against Cancer (ARTAC), 75015 Paris, France
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