OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
OBM Neurobiology publishes research articles, technical reports and invited topical reviews. Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.
Oxidative Stress and Inflammatory Responses in Neurodegenerative Diseases
Submission Deadline: March 15, 2019 (Open) Submit Now
Mohammad Moshahid Khan, PhD
Assistant Professor, Departments of Neurology and Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, United States
Email: [email protected]
Research Interests: Neuroscience; Pharmacology; Neurodegeneration; Neuroinflammation; Parkinson’s Disease; Stroke; Alzheimer’s Disease; Multiple Sclerosis and Traumatic Brain Injury
About This Topic
Inflammation and Oxidative stress are common features of chronic neurodegenerative diseases of the central nervous system. Chronic inflammation is characterized by longstanding microglial activation followed by sustained release of inflammatory mediators, which aid in enhanced nitrosative and oxidative stress. The sustained release of inflammatory mediators propels the inflammatory cycle by increased microglial activation, promoting their proliferation and thus stimulating enhanced release of inflammatory factors. Elevated levels of several cytokines and chronic neuroinflammation have been associated with many neurodegenerative disorders of central nervous system like age-related macular degeneration, Alzheimer disease, multiple sclerosis, Parkinson’s disease, Huntington’ disease, and tauopathies. In this special issue, we aim to the introduction of the relative research the basic mechanisms of neuroinflammation and oxidative stress, the characteristics of neurodegenerative diseases, and the main immunologic responses in CNS neurodegenerative disorders. Original research reports, review articles, communications, and perspectives are welcome in all areas pertinent to the topic. All accepted papers will be published totally free of charge.
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Neurodegenerative diseases; Inflammation; Oxidative stress; Cytokines and Inflammatory factors
Title: Correlation Between Neuroimaging and Epigenetics in Chronic Discogenic Lumbar Pain
Authors: M.Marchesini 1, N. Peroni 2, M. Allegri 3
1. Pain Medicine Unit, ICS S. Maugeri Pavia, Italy
2. Anesthesia, Intensive Care Pain Medicine Department, San Matteo Pavia, Italy
3. Pain Therapy Service, Policlinico Monza Hospital, Monza Italy
Title: Oxydative stress and low grade inflammation in electrohypersensitivity self-reporting patients
Authors: Philippe Irigaray, Dominique Belpomme
Affiliation: Association for Research Against Cancer (ARTAC), 75015 Paris, France
Alina Khan, Tengfei Wan, Catherine Hunter, Pavel Schweizer, Abbas Ishaq, Shobha Nagarathanam, Julia Morris, Minyu Chan, Gabriele Saretzki
Received: March 13, 2019; Published: August 01, 2019; doi:10.21926/obm.neurobiol.1903036