Cardiac Allograft Vasculopathy: A Review of Risk Factors and Pathogenesis
by
Mrudula Munagala
and
Anita Phancao
Mrudula Munagala
and
Anita Phancao
Abstract
Heart transplant remains the gold standard therapy for patients with end stage heart disease and offers improved survival and quality of life. Significant progress has been achieved in improving one year mortality after heart transplantation. Nonetheless, long-term graft survival has not changed significantly over the past few decades. Long term survival of heart transplant recipients is limited by chronic rejection, cardiac allograft vasculopathy (CAV), and malignancy. CAV is a major contributo [...]