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Open Access Research Article

Long-Term Exposure to Fine Particulate Matter (PM_2.5) and Cardiovascular Disease Mortality among Renal Transplant Recipients

by

Salem Dehom ,

Synnove Knutsen ,

David Shavlik ,

Khaled Bahjri ,

Hatem Ali ,

Lance Pompe and

Rhonda Spencer-Hwang

Received: 11 August 2019; Published: 17 December 2019; doi: 10.21926/obm.transplant.1904095

Abstract

Background: Substantial evidence has been used to establish links between air pollution and increased risks of overall health morbidity and mortality, especially for respiratory and cardiovascular diseases. However, very few investigations have explored these relationships among highly sensitive pop [...]

Open Access Review

Modelling Recurrent Primary Biliary Cholangitis and Primary Sclerosing Cholangitis as Infectious Diseases Following Liver Transplantation

by

Victor Dong ,

Aldo Montano-Loza and

Andrew Mason

Received: 19 November 2019; Published: 13 December 2019; doi: 10.21926/obm.transplant.1904094

Abstract

Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are idiopathic and progressive autoimmune hepatobiliary disorders that lead to liver failure and a need for liver transplantation in a proportion of individuals with poorly controlled disease. It is currently thought that an [...]

Open Access Review

Therapeutic Apheresis in Prevention and Treatment of Antibody-Mediated Rejection of Renal Allografts

by

Maurizio Salvadori MD and

Aris Tsalouchos

Received: 13 October 2019; Published: 02 December 2019; doi: 10.21926/obm.transplant.1904093

Abstract

Antibody-mediated rejection represents a significant barrier to favourable long-term outcomes after kidney transplantation and is the most common cause of allograft failure. Therapeutic apheresis techniques associated with other treatments, such as immunosuppressive drugs, are commonly used in the p [...]

Open Access Research Article

Incidence, Location, and Natural History of Perihepatic Fluid Collections after Orthotopic Liver Transplantation

by

Sumail Bhogal ,

Matthew Minn ,

Pranay Krishnan and

Reena C. Jha

Received: 18 February 2019; Published: 18 November 2019; doi: 10.21926/obm.transplant.1904092

Abstract

Objective: The purpose of this study was to evaluate the common locations of perihepatic fluid collections after liver transplantation, assess their complexity, and understand their natural history and clinical significance. Materials and Methods: A retrospective analysis of 189 postoperative ortho [...]

Open Access Case Report

Toxoplasmosis: “An Often Forgotten Cause for Fever of Unknown Origin in Liver Transplant Recipients”. Case Report and Review of Literature

by

Jose A. Morillas and

Sherif Beniameen Mossad

Received: 24 October 2019; Published: 18 November 2019; doi: 10.21926/obm.transplant.1904091

Abstract

Toxoplasmosis in liver transplantation (LT) is uncommon, especially in the current era of universal prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) for Pneumocystis jirovecii pneumonia (PJP). Here we present a case of a 55-year-old woman LT recipient, on dapsone or PJP prophylaxis due to su [...]

Open Access Original Research

Combination, Sequential Therapies Incorporating Tocilizumab Decrease the Progression of Chronic Lung Allograft Dysfunction (CLAD) after Lung Transplantation: Initial Clinical Experience

by

David J. Ross ,

Abbas Ardehali ,

Christine Natori and

John A. Belperio

Received: 19 September 2019; Published: 07 November 2019; doi: 10.21926/obm.transplant.1904090

Abstract

INTRODUCTION: TH-17 and IL-6 interactions and detrimental biologic effects have been shown in rodent models of Chronic Lung Allograft Dysfunction (CLAD). Similarly, these pathways have been found to be upregulated in human CLAD. Tocilizumab (TCZ), a humanized monoclonal antibody targets the IL-6 r [...]

Open Access Case Report

A Silent and Very Early Post-Liver Transplant Death by Candida Arteritis

by

Kyungmin Ko ,

Juan Guerra and

David Garvin

Received: 29 August 2019; Published: 28 October 2019; doi: 10.21926/obm.transplant.1904089

Abstract

Background: Graft site candidiasis is a serious complication after solid organ transplantation, often presenting as invasive arteritis leading to graft loss or even death. Case Report: We report a case of anastomotic site candidiasis leading to arterial rupture and death at postoperative day 10 with [...]

Open Access Original Research

Oral Management in Pre-HSCT Patients: An Evaluation of Oral and Systemic Complications

by

Renato Pol ,

Tiziana Ruggiero ,

Luisa Giaccone ,

Davide Camisassa ,

Andrea Spadafora ,

Giulia Rivetti ,

Marta Bezzi and

Stefano Carossa

Received: 14 June 2019; Published: 21 October 2019; doi: 10.21926/obm.transplant.1904088

Abstract

Objective Hematopoietic stem cell transplant has to be preceded by chemotherapy and radiotherapy. The following neutropenia and thrombocytopenia could be the cause of post transplant complications. Patient undergoing transplantation need to be eradicated of any possible infectious focus. Nowadays th [...]

Open Access Case Report

The Surgical Approach for Obtaining Abdominal Wall Closure in Renal Transplant Recipients with Temporary or Permanent Loss of Fascial Integrity Following Emergency Reoperative Surgery

by

Susanna Lam ,

Jerome Laurence and

Deborah Verran

Received: 01 July 2019; Published: 08 October 2019; doi: 10.21926/obm.transplant.1904087

Abstract

A range of corrective surgical procedures may be required in adult renal transplant recipients who sustain loss of integrity of the abdominal wall in the first month postoperatively. Where this involves the fascia, such as in acute fascial dehiscence or in renal allograft compartment syndrome, more [...]

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