A Rare and Complex Case of Multifactorial Thrombotic Microangiopathy in A Kidney Transplant Recipient: Interplay Between Antibody Mediated Rejection, Tacrolimus Toxicity, Cytomegalovirus Disease and BNT162b2mRNA Vaccine
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A Rare and Complex Case of Multifactorial Thrombotic Microangiopathy in A Kidney Transplant Recipient: Interplay Between Antibody Mediated Rejection, Tacrolimus Toxicity, Cytomegalovirus Disease and BNT162b2mRNA VaccineAbstract Thrombotic microangiopathy (TMA) in kidney transplant recipients is uncommon and difficult to manage, often with poor graft outcomes [1]. This is a complex and interesting case of an older, highly sensitised kidney transplant recipient who presented with de novo post-transplant [...] 79 1131 |
Lung Transplantation for COVID-19 Related Lung Disease: A Follow-Up Study of Outcomes from a Medium-Size Lung Transplant Programdby
![]() ![]() ![]() ![]() ![]() ![]() Abstract In the United States of America, COVID-19 acute respiratory distress syndrome (ARDS) and post-COVID pulmonary fibrosis (PCPF) are raising indications for lung transplant (LT). Another indication for LT is underlying fibrosis with SARS-CoV-2 induced interstitial lung disease exacerbation or rapid pro [...] 105 1281 |
BK Virus Infection and Its Management in Renal Transplantation: An Updateby
![]() ![]() ![]() ![]() ![]() ![]() Abstract BK virus (BKV) is a common opportunistic pathogen in kidney transplant recipients and one of the most challenging causes of allograft dysfunction and loss. Although over-immunosuppression remains the primary risk factor for BKV infection after transplantation, ma [...] 169 1850 |
Identification of Potential Predictive and Diagnostic Urinary Biomarkers for Acute Rejection in Renal Transplant Recipients: A Proteomics Studyby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Acute rejection (AR) is one of the main predictors of long-term survival of allograft. The development of noninvasive diagnostic biomarkers of AR is an unmet need for the timely detection. This study aimed to identify novel detective biomarkers of AR by analyzing the urine proteome profile of transp [...] 120 1498 |
Biomarkers in the Management of the Lung Transplant Allograft: A Focus on Donor-derived Cell-free DNAAbstract Advances in the use of molecular biomarkers to guide management of lung transplant recipients are emerging. One such biomarker, donor-derived cell-free DNA (dd-cfDNA), has the potential to alter traditional approaches of lung transplant management, including the detection of acute reject [...] 108 1438 |
Kidney Transplantation in Nigeria: A Single Centre’s Early Surgical Experience and Outcomesby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract With the rise in the population of patients with End-stage Renal Disease (ESRD) in Nigeria, there is an increased demand for Renal Replacement Therapy (RRT) including kidney transplantation (KT). We present our initial surgical experience and early outcomes with KT at a Nigerian transplant center ov [...] 107 2074 |
Open Access Short Communication Surgical Tips for Improving Success Rate of Deep Anterior Lamellar Keratoplasty in Keratoconusby
![]() ![]() ![]() ![]() ![]() ![]() Abstract This article aims to provide some personal surgical tips to increase the success rate of deep anterior lamellar keratoplasty (DALK), a very advantageous yet complex procedure for treating keratoconus. The most troublesome surgical step is obtaining a successful pneumatic dissection of the deep strom [...] 110 1471 |
Prospects of Platelet-Rich Plasma in Regenerative Medicineby
![]() ![]() Abstract Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regener [...] 152 1940 |
Effect of Foot Reflexology on Laboratory Tests after Kidney Transplantation Surgery: A Secondary Analysis of a Parallel Randomized Controlled Trial Studyby
![]() ![]() ![]() ![]() ![]() Abstract Foot reflexology has improved numerous physical and psychological symptoms in patients. The researchers in this study aimed to investigate the effect of foot reflexology on laboratory parameters, intake/output/weight and medication regimen after kidney transplant surgery. The research was a secondar [...] 121 1878 |
Successful Kidney Transplantation of Two Patients with Donors Positive for Severe Acute Respiratory Syndrome Coronavirus InfectionAbstract Despite preventative measures, including vaccination, severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection may result in severe illness, particularly in immunosuppressed transplant recipients. This has had a negative impact on organ donation and transplantation rates. However, the ri [...] 135 1620 |
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