TY  - JOUR
AU  - Stasi, Alessandro
AU  - Thongpravati, Onnida
PY  - 2024
DA  - 2024/05/29
TI  - Biotechnology Innovation in Do-It-Yourself (DIY) Gene Editing: A Call for a New Regulatory Framework
JO  - OBM Genetics
SP  - 238
VL  - 08
IS  - 02
AB  - The expansion of do-it-yourself (DIY) gene editing, facilitated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology, has catalyzed a significant shift in scientific research and biotechnology innovation. This movement is propelled by a community-driven approach that challenges the traditional confines of scientific exploration, allowing amateur scientists to perform sophisticated biological experiments. While this democratization fosters inclusivity and accelerates innovation, it simultaneously introduces significant biosecurity risks. The possibility of unregulated gene editing leading to the unintentional creation of harmful organisms or the deliberate engineering of pathogens underscores the need for a new regulatory framework. This paper explores the implications of DIY biology within the context of public health, environmental safety, and biosecurity, highlighting the urgency for adaptive policies that balance scientific freedom with security. It proposes integrating community-driven regulatory practices with formal oversight mechanisms by examining biosecurity implications, ethical considerations, and the potential for misuse. Additionally, the role of decentralized autonomous organizations (DAOs) is explored as a novel approach to transforming governance within the domain of DIY gene editing, particularly in the context of CRISPR research.
SN  - 2577-5790
UR  - https://doi.org/10.21926/obm.genet.2402238
DO  - 10.21926/obm.genet.2402238
ID  - Stasi2024
ER  -