OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes research articles, reviews, communications and technical notes, etc. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 15.0 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).
Submission Deadline: April 30, 2018 (Open) Submit Now
Miodrag Stojkovic, PhD
Professor, Human Genetics, Faculty of Medical Sciences, University of Kragujevac, Spebo Medical, Leskovac, Serbia
Research Interests: embryology; stem cell biology; differentiation; regenerative medicine; reprogramming
Professor of Genetics, School of Biosciences, University of Kent, Director of the Centre for Interdisciplinary Studies of Reproduction (CISoR), Canterbury, Kent, CT2 7NJ, UK
Research Interests: genetics; chromosomes; cytogenetics; infertility; genome evolution
About This Topic
Reproductive health is a value for the community. Unfortunately, both female and male infertility is increasing in our societies and part of this is due to genetic factors. This leads to an increasing demand for access to reproductive counseling and assisted reproductive treatment (ART). In addition, as an important part of reproductive medicine, reproductive genetics focuses on reproductive options for couples with increased risks of transmitting genetic abnormalities and diseases. These include preimplantation genetic diagnosis and prenatal diagnosis.
Furthermore, reproductive genetics involves the more basic analysis of gametogenesis and the resulting oocytes, sperm cells, embryos and other reproductive tissues of mammalian and non-mammalian origin, including embryonic stem cells.
In this special issue of OBM Genetics we summarize the present knowledge and prospects of reproductive genetics through scientific and clinical activities with the aim to highlight key factors involved in early development and reproduction. With worldwide leaders in this rapidly increasing field, the special issue presents detailed picture of how reproductive genetics influences and assists biology of gametes and embryos, endometrial receptivity, fertility, ART and reproductive health. For sure, the issue is an essential guideline to understand basic mechanisms and improve medical treatments.
Received: 01 January 2019; Published: 29 March 2019; doi: 10.21926/obm.genet.1901070
The mitochondria of the oocyte are a prominent source of energy metabolism as well as mitochondrial DNA that will later populate the cells of the offspring. Recent discoveries provided new insight into the physiology of the mitochondria and its unique genetics. The concept of heteroplasmy defined as the presence of more than one type of mitoch [...]
Received: 05 June 2018; Published: 23 July 2018; doi: 10.21926/obm.genet.1803024
Both preimplantation genetic testing and prenatal testing are powerful tools to tackle the transmission of inherited disorders in families carrying the diseases from generation to generation. This article presents an overview of the current landscape of both methods and identifies the pros and cons of each of these reproductive options.
Unusual Ways to Lose a Y Chromosome and Survive with Changed Autosomes: a Story of Mole Voles Ellobius (Mammalia, Rodentia)
Received: 16 May 2018; Published: 22 July 2018; doi: 10.21926/obm.genet.1803023
When does reproduction start? An old question of the chicken and the egg is even more complicated in relation to mole voles Ellobius. First, ‘chicken’ should be a female, and males are obviously involved in reproduction too because zygote is a result of sperm and oocyte fusion. But nobody knows how males appear in Ellobius lacking the [...]
Received: 16 April 2018; Published: 12 June 2018; doi: 10.21926/obm.genet.1802022
We address an ongoing controversy over what health-care providers tell prospective parents about Down Syndrome (DS). In the view of critics, including many parent, disability-rights, and anti-abortion activists, the messages that health-care professionals transmit to pregnant women and their partners are distorted. OB-GYNs, primary-care provid [...]
To prevent robots and page crawlers from submitting fraudulent forms, complete verification to prove that you are a human.