TY  - JOUR
AU  - Anaya-Prado, Roberto
AU  - Cárdenas-Fregoso, Ana P.
AU  - Reyes-Perez, Ana M.
AU  - Ortiz-Hernandez, Danielle M
AU  - Quijano-Ortiz, Montserrat
AU  - Delgado-Martinez, Monica V
AU  - Pelayo-Romo, Ana S
AU  - Anaya-Fernandez, Roberto
AU  - Anaya-Fernandez, Michelle M
AU  - Azcona-Ramirez, Consuelo C
AU  - Garcia-Ramirez, Ivan F
AU  - Guerrero-Palomera, Miguel A
AU  - Gonzalez-Martinez, Daniel
AU  - Guerrero-Palomera, Citlalli S
AU  - Paredes-Paredes, Karina
AU  - Garcia-Perez, Claudia
PY  - 2024
DA  - 2024/07/16
TI  - The Biomolecular Basis of Gut Microbiome on Neurological Diseases
JO  - OBM Neurobiology
SP  - 232
VL  - 08
IS  - 03
AB  - The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and brain function has been associated with the development and pathogenesis of neuropsychiatric diseases. This review discusses current studies targeting the regulation and modulation of GM in nerve, neuroendocrine, and immune pathways. Thus, we analyze current evidence on transcription, changes in composition, and specific interactions between the gut and brain from a biomolecular perspective. Special attention is paid to mood disorders and neurodegenerative diseases.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.2403232
DO  - 10.21926/obm.neurobiol.2403232
ID  - Anaya-Prado2024
ER  -