TY  - JOUR
AU  - De Jesus Encarnacion Ramirez, Manuel
AU  - Konovalov, Nikolay
AU  - Kaprovoy, Stanislav
AU  - Chmutin, Gennady
AU  - Cerna, Geovany Venegas
AU  - Nurmukhametov, Renat
AU  - Rosario, Andreina Rosario
AU  - Yakovlevich, Kalin Ivan
AU  - Lafuente, Jesus
AU  - Suero Molina, Eric
AU  - Montemurro, Nicola
PY  - 2024
DA  - 2024/09/09
TI  - Illuminate Resection Pathways with Fluorescence Guidance in Glioma Surgery: Case Reports and Systematic Review
JO  - OBM Neurobiology
SP  - 244
VL  - 08
IS  - 03
AB  - Gliomas are the most common brain tumor in adults, with a poor prognosis despite intensive treatments. Complete surgical resection is difficult due to its infiltrative growth, but aggressive surgery improves outcomes. Fluorescence-guided surgery (FGS) is used to distinguish tumor tissue during surgery. 5-Aminolevulinic Acid (5-ALA) is a crucial fluorescent agent in FGS, transforming into a molecule that accumulates in tumor cells. We presented a 34-year-old female with a high-grade glioma in the left parietal lobe who underwent fluorescence-guided tumor resection using 5-ALA was reported. In addition, a review of the literature on fluorescence in glioma surgery, searching databases like PubMed and SCOPUS from 2021 to 2023, was performed. Fifteen papers were included in our review. This technique ensured gross-total tumor resection while preserving neurological function. FGS improves tumor identification, surgical outcomes, and survival.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.2403244
DO  - 10.21926/obm.neurobiol.2403244
ID  - De Jesus Encarnacion Ramirez2024
ER  -