TY  - JOUR
AU  - Lixi, Filippo
AU  - Pintus, Benedetta
AU  - Giannaccare, Giuseppe
PY  - 2024
DA  - 2024/06/07
TI  - Management of Calcareous Corneal Degeneration from Medication Washout to Corneal Transplantation. Case Series and Review of the Literature
JO  - OBM Transplantation
SP  - 218
VL  - 08
IS  - 02
AB  - Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the management of this disorder. Herein, two cases of calcareous degeneration occurring postoperatively in patients undergoing surgery for retinal detachment (case #1) and glaucoma (case #2) were reported. Despite normal serum calcium and phosphate levels, the patients developed corneal calcification after using topical steroid-phosphate drops. Treatment involved discontinuation of topical therapy and substitution with unpreserved phosphate-free lubricants. While case #1 resolved with conservative measures, which allowed a satisfactory visual recovery, case #2 required superficial keratectomy due to refractory calcification. Therefore, a correct diagnosis, careful lesion analysis, and tailored management are advisable in corneal calcification, with conservative measures being effective in most cases. At the same time, surgical intervention is necessary in refractory or advanced diseases.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2402218
DO  - 10.21926/obm.transplant.2402218
ID  - Lixi2024
ER  -