OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
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We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor.
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Rational Utilization of Donor Organs
Submission Deadline: November 30, 2021 (Open) Submit Now
Darren Stewart, M.S.
Research Department, United Network for Organ Sharing, Richmond, Virginia, USA
Research Interests: Solid organ transplantation; optimizing deceased donor kidney utilization; experimentation using behavioral science to optimize organ allocation; characterizing transplant patient outcomes on the waiting list and post-transplant; evaluating the effectiveness of the organ allocation system and identifying ways to improve it; measuring equity in organ allocation; identifying high versus low-performing transplant institutions to cultivate system-wide process improvement; evaluating how advances in statistical methods can be leveraged in the field of organ transplantation
About This Topic
Due to increasing prevalence of chronic disease worldwide, the demand for solid organ transplants generally far exceeds the available supply of transplant-quality organs in most countries. Yet in the face of such scarcity, why do many parts of the world struggle to maximize the utilization of donor organs, as evidenced by high organ discard rates, high offer refusal rates, and underutilization of potential donors?
In this issue, we seek research that advances our understanding of the drivers behind seemingly irrational underutilization of deceased donor organs, both at a national/system level and individual (institution/clinician/patient) level. We hope to move the conversation toward solutions that foster more rational organ utilization decisions, through levers such as
- Allocation policy advancements that balance concerns of utility, system efficiency / organ utilization, and equity
- Data-driven, clinical decision support tools for clinicians and patients that mitigate biases and uncertainty in decision-making
- Strategic use of performance metrics to drive institution and system-level utilization of organs that reduces risk-aversion and maximizes the benefit to organ failure patients
- A modified transplant financial model that reduces or avoids disincentives for organ underutilization
- Clinical innovations (e.g., perfusion; organ “repair”; donor management) to improve outcomes of less-than-perfect organs
Research is sought on organ (kidney, liver, lung, heart, pancreas, or intestine) utilization-related dynamics such as organ recovery rate patterns; offer acceptance/refusal patterns and reasons; the influence of performance metrics/monitoring; behavioral economics; allocation policy simulations aimed at increasing utilization; the role of transplant finances; and transplant outcomes.
International comparisons are encouraged.
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