OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 6 days from acceptance to publication (median values for papers published in this journal in the first half of 2019, 1-2 days of FREE language polishing time is also included in this period).

Free Publication in 2019
Current Issue: 2019  Archive: 2018 2017

Volume 3,Issue 3

Open Access Concept Paper

The “PRIMING, TIMING, MIMING” Model of Individualized Behavioural Care Planning for Residents with Dementia

Lindy A. Kilik
Received: July 30, 2019; Published: September 29, 2019; doi:10.21926/obm.geriatr.1903076

Open Access Original Research

Sleep Symptoms Differentially Predict Cognition in Younger and Older-Onset Parkinson's Disease

Maria E. Pushpanathan, Andrea M. Loftus, Natalie Gasson, Meghan G. Thomas, Romola S. Bucks
Received: May 13, 2019; Published: September 23, 2019; doi:10.21926/obm.geriatr.1903075

Open Access Review

Management of Neuropsychiatric Symptoms of Dementia: A Comprehensive Review of the Current Literature

Laura Suarez, Reem M.A. Shafi, Maria I. Lapid
Received: May 14, 2019; Published: September 16, 2019; doi:10.21926/obm.geriatr.1903074

Open Access Review

Facilitation of Social Support through Negative Allosteric Modulation of α5-Associated GABAA Receptors: A Novel Mechanism for the Treatment of Depression, Agitation, and Aggression in the Elderly

Jeffrey M. Witkin, Lalit K. Golani, Rok Cerne, Md. Toufiqur Rahman, Guanguan Li, Michael M. Poe, James M. Cook, Jodi L. Smith
Received: May 05, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903073

Open Access Original Research

Wisdom of the Elders: Narratives Enhancing Trainees’ Attitudes Towards Aging

James S. Powers, Destiny O. Birdsong, Kemberlee R. Bonnet, Neena R. Kapoor, Jamaria J. Southward, Ifeoma Nwankwo, David G. Schlundt
Received: April 25, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903072

Open Access Original Research

Atrial Fibrillation, Anticoagulation, and Major Bleeding Episodes in Geriatric Patients at the Risk of Falling

Lennaert Zwart, Tjeerd Germans, Suat Simsek, Jaap Ruiter, René Jansen
Received: May 22, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903071

Open Access Review

Shedding Light on Manic Syndromes and Dementia

Gabriele Cipriani, Sabrina Danti, Cecilia Carlesi, Claudio Lucetti, Angelo Nuti, Mario Di Fiorino
Received: March 27, 2019; Published: August 16, 2019; doi:10.21926/obm.geriatr.1903070

Open Access Original Research

Intranasal Insulin in Alzheimer’s Disease: A Pragmatic Account

Sara Schatz, Melvin Gonzalez Rivera
Received: March 15, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903069

Open Access Review

The Value Given and Presupposed in Person-Centred Dementia Care

Stephen Ames
Received: April 08, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903068

Open Access Original Research

Differential Effects of Social Network on Health in Later Life and the Moderating Role of Depression

Shira Peleg, Howard Litwin
Received: March 23, 2019; Published: August 12, 2019; doi:10.21926/obm.geriatr.1903067

Open Access Case Report

Personalised Medicine for Dementia: Collaborative Research of Multimodal Non-pharmacological Treatment with the UK National Health Service (NHS)

Garuth Chalfont, Jane Simpson, Sarah Davies, David Morris, Ruth Wilde, Leigh Willoughby, Christine Milligan
Received: April 08, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903066

Open Access Review

A Model for Understanding Hispanic/Latino Family Caregiving for Older Adults

Hsueh-Fen S. Kao, Maria A. Amaya
Received: May 19, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903065

Open Access Review

Insights from Yeast on Oxidative Stress in Alzheimer’s Disease, Focusing on Ahp1p/Prx5

Ian Macreadie, Sudip Dhakal
Received: May 05, 2019; Published: July 17, 2019; doi:10.21926/obm.geriatr.1903064

Open Access Review

Curing Alzheimer’s Disease: Myriad Causes and Myriad Cures Await

Mario D. Garrett
Received: June 12, 2019; Published: July 16, 2019; doi:10.21926/obm.geriatr.1903063

Open Access Review

Role of Artificial Intelligence (AI) Art in Care of Ageing Society: Focus on Dementia

Tracy Harwood, John Maltby, Elizabeta B. Mukaetova-Ladinska
Received: March 28, 2019; Published: July 15, 2019; doi:10.21926/obm.geriatr.1903062

Open Access Original Research

Estimating Potential Cost Containment through Provision of Unplanned Institutional Respite Services to Support Home-Based Care within Japan’s Long-Term Care Insurance System

Yoko Moriyama, Timothy Bolt, Marilyn Luptak, Nanako Tamiya
Received: February 19, 2019; Published: July 09, 2019; doi:10.21926/obm.geriatr.1903061

Open Access Review

Parting with the Concept of Alzheimer’s Disease in Senium

Pavel Kalvach, Martin Vogner
Received: March 30, 2019; Published: July 08, 2019; doi:10.21926/obm.geriatr.1903060

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