Open Access Original Research

Effects of Enriched Thematic Multi-Sensory Stimulation on BPSD in A Beach Room: A Pilot Study among Nursing-Home Residents with Dementia

Renate Verkaik, Iris van der Heide, Eugenie van Eerden, Peter Spreeuwenberg, Erik Scherder, Anneke L. Francke
Received: April 02, 2019; Published: December 11, 2019; doi:10.21926/obm.geriatr.1904092

Abstract: Background: Studies of the effectiveness of psychosocial interventions indicate that sensory stimulation is a promising approach to reduce psychological and behavioural disturbances in people with dementia. A relatively new approach is enriched multi-sensory stimulation. Enriched multi-sensory stimu [...]

Open Access Original Research

Exploring Quality of Sleep, Perceived Stress and Resilience in Cancer Survivorship: A Feasibility Study of Mindfulness in Motion

Maryanna D. Klatt, Emaline Wise, Olivia Gabram, Megan Huber, Lai Wei, Mira Katz
Received: April 02, 2019; Published: December 11, 2019; doi:10.21926/obm.neurobiol.1904047

Abstract: (1) Background: The global principles of Mindfulness-Based Stress Reduction (MBSR) have led to the creation of Mindfulness-Based Interventions (MBIs), which are interventions that retrain the mind to modify its usual stress response to increase coping and resilience. Mindfulness in Motion (MIM) is a [...]

Open Access Review

Depression in the Elderly–Epidemiology, Diagnosis, Special Aspects, and Treatment Options

Horst J. Koch
Received: August 06, 2019; Published: December 04, 2019; doi:10.21926/obm.geriatr.1904091

Abstract: The prevalence of Late-life Depression (LLD) is estimated between 10 and 15 % and therefore LLD is a considerable world-wide problem. The psychopathology is not substantially different from that of depressive episodes in young adults, but somatic complaints in combination of end-of-life perspective [...]

Open Access Review

The Association between Bone Turnover Markers and Fracture in People with Diabetes: A Systematic Review and Meta-Analysis

Katrine Hygum, Jakob Starup-Linde, Torben Harsløf, Bente Langdahl
Received: August 29, 2019; Published: December 04, 2019; doi:10.21926/obm.geriatr.1904090

Abstract: Background: The increased fracture risk in persons with diabetes is underestimated by conventional fracture predictors. The aims of this study were to conduct a systematic review and a meta-analysis to compare the levels of bone turnover markers (BTM) in persons with diabetes with and without fractu [...]

Open Access Hypothesis

Combination of the Hansemann-Boveri, Warburg, and Knudson Theories of Cancer, Based on Failure of Missegregation Damage Mitigation

Kjeld C. Engvild
Received: July 17, 2019; Published: December 3, 2019; doi:10.21926/obm.genet.1904100

Abstract: The Hansemann-Boveri aneuploidy theory, the Warburg aerobic glycolysis theory, and the Knudson two-hit mutation theory can be seen as different aspects of a theory where the very common chromosome missegregation damage is mitigated by several quite different mechanisms. Cancer only occurs when all o [...]

Open Access Review

Therapeutic Apheresis in Prevention and Treatment of Antibody-Mediated Rejection of Renal Allografts

Maurizio Salvadori, Aris Tsalouchos
Received: October 13, 2019; Published: December 02, 2019; doi:10.21926/obm.transplant.1904093

Abstract: Antibody-mediated rejection represents a significant barrier to favourable long-term outcomes after kidney transplantation and is the most common cause of allograft failure. Therapeutic apheresis techniques associated with other treatments, such as immunosuppressive drugs, are commonly used in the p [...]

Open Access Original Research

Automated Movement Feedback for Recovering Independence in the Sit-to-Stand Movement in an Older Population: A Pilot Randomised Controlled Trial of a Novel System

Siu Fai Ho, Avril Thomson, Tricia Moylan, Julie McGuckin, Andrew Kerr
Received: September 23, 2019; Published: December 02, 2019; doi:10.21926/obm.geriatr.1904089

Abstract: Background The sit-to-stand (StS) movement is a frequently performed task critical to independent living that is both difficult to perform and associated with falls in older populations. Consequently, the recovery of this movement through supervised practice is a priority during the rehabilitation [...]

Open Access Review

Alzheimer’s Disease: Is a Dysfunctional Mevalonate Biosynthetic Pathway the Master-Inducer of Deleterious Changes in Cell Physiology?

Arnold De Loof, Liliane Schoofs
Received: October 03, 2019; Published: November 29, 2019; doi:10.21926/obm.neurobiol.1904046

Abstract: The awareness is growing that the proteins amyloid-beta (Aβ) and tau are rather a result of Alzheimer’s disease (AD) than its cause. Similarly, doubt reigns about the degree of causality of high plasma cholesterol/lipids (the fat connection) and of prenylation. An important conceptual addition to [...]

Open Access Review

Nutrition, Cancer Genetics and Epigenetics

Kenneth Lundstrom
Received: October 1, 2019; Published: November 28, 2019; doi:10.21926/obm.genet.1904099

Abstract: A strong association has been established between nutrition and disease risk confirmed by epidemiological data and meta-analysis. In the context of cancer, unhealthy diets have been demonstrated to increase the risk of disease. On the other hand, major dietary interventions and lifestyle changes hav [...]

Open Access Original Research

Social Engagement and Task Complexity: Physical Activity Characteristics and Executive Function Among Older Adults

Lyndsie Koon, Robert Brustad, Megan Babkes Stellino
Received: May 15, 2019; Published: November 27, 2019; doi:10.21926/obm.icm.1904064

Abstract: Physical activity participation has been found to have a positive impact on cognitive function across a lifespan. For older adults, qualitative variables with the physical activity context may influence cognition than quantitative variables (e.g., intensity, duration). The purpose of this study was [...]

Open Access Original Research

Diversity in the Bacterial Genus Dickeya Grouping Plant Pathogens and Waterways Isolates

Jacques Pédron, Frédérique Van Gijsegem
Received: July 25, 2019; Published: November 26, 2019; doi:10.21926/obm.genet.1904098

Abstract: Background: The Dickeya genus comprises aggressive soft rot plant pathogens with wide geographic distribution and host ranges. Ten Dickeya species have been characterised. Seven of them (D. chrysanthemi, D. dadantii, D. dianthicola, D. fangzhongdai, D. solani, D. paradisiaca, D. zeae) group causati [...]

Open Access Case Report

Physical Illness and Emotional Expression in Late Life

Elizabeth Midlarsky
Received: August 18, 2019; Published: November 25, 2019; doi:10.21926/obm.geriatr.1904088

Abstract: Louise H., Ph.D was referred to me by her long-term primary care physician (PCP) who was certain that his patient was seriously depressed and in need of medication and possibly psychotherapy. My own assessment, in consultation with a neurologist, was that Louise’s problems with coping were primaril [...]

Open Access Research Article

Balance and Fall Rates are Associated with Chronic Pain, and Improve with Yoga

Arlene A. Schmid, Marieke Van Puymbroeck, Christine A. Fruhauf, Laura A. Swink, Jennifer D. Portz
Received: September 29, 2019; Published: November 25, 2019; doi:10.21926/obm.geriatr.1904087

Abstract: Background: Falls are relatively common in older adults and are associated with chronic pain. Chronic pain may even be a predictor of falls in older adults. However, this relationship has not been studied in adults <65 years of age. The purpose of this study was to examine the relationship betwee [...]

Open Access Review

Engineering Bacterial Cellulose for Diverse Biomedical Applications

Sana Sandhu, Anindita Arpa, Xi Chen, Rahul Kumar, Justyn Jaworski
Received: September 15, 2019; Published: November 25, 2019; doi:10.21926/rpm.1904006

Abstract: Increasing interest in bacterial cellulose due to the huge potential which exists for the development of this new biomaterial for medical applications has been met with recent growth in research in engineering this unique microbial manufactured material. The mechanical properties, porosity, and bioc [...]

Open Access Case Report

Hypereosinophilia with Gastrointestinal Involvement: A Case Report

Mauro Turrin, Barbara Mariotti, Isabella Schiavon, Serena Battista
Received: September 29, 2019; Published: November 22, 2019; doi:10.21926/obm.hg.1904040

Abstract: Hypereosinophilic syndrome is currently defined by an absolute blood eosinophil count of more of 1500 cell per μL for more than 1 month and by multiorgan system infiltration. Eosinophilic colitis is an exceptionally rare inflammatory condition in which eosinophils infiltrate the colonic gut. It repr [...]

Open Access Research Article

Solvatochromism of Copper(II) Complexes Derived from Trifluoroacetylacetone and Dinitrogen Ligands

Wolfgang Linert, Azza. A. Abou-Hussein, Nelly H. Mahmoud
Received: September 18, 2019; Published: November 19, 2019; doi:10.21926/acr.1904001

Abstract: Mixed ligand Cu(II) complexes of the empirical formula; [Cu(L)(TFAA)]X, where L represents 2,2´-bipyridine (Bipy), 1,10´-phenanthroline (Phen) or 4,7-diphenyl-1,10´- phenanthroline (Dphen), 1,1,1-Trifluoro-2,4-pentanedione (HTFAA) and X is the counter ion (BF4- or ClO4-) have been synthesized and c [...]

Open Access Research Article

Incidence, Location, and Natural History of Perihepatic Fluid Collections after Orthotopic Liver Transplantation

Sumail Bhogal, Matthew Minn, Pranay Krishnan, Reena C. Jha
Received: February 18, 2019; Published: November 18, 2019; doi:10.21926/obm.transplant.1904092

Abstract: Objective: The purpose of this study was to evaluate the common locations of perihepatic fluid collections after liver transplantation, assess their complexity, and understand their natural history and clinical significance. Materials and Methods: A retrospective analysis of 189 postoperative ortho [...]

Open Access Case Report

Toxoplasmosis: “An Often Forgotten Cause for Fever of Unknown Origin in Liver Transplant Recipients”. Case Report and Review of Literature

Jose A. Morillas, Sherif Beniameen Mossad
Received: October 24, 2019; Published: November 18, 2019; doi:10.21926/obm.transplant.1904091

Abstract: Toxoplasmosis in liver transplantation (LT) is uncommon, especially in the current era of universal prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) for Pneumocystis jirovecii pneumonia (PJP). Here we present a case of a 55-year-old woman LT recipient, on dapsone or PJP prophylaxis due to su [...]

Open Access Original Research

Evaluation of the Prevalence of Screening for Dysphagia among Older People Admitted to Medical Services – An International Survey

David Smithard, Signe Westmark, Dorte Melgaard
Received: September 15, 2019; Published: November 15 , 2019; doi:10.21926/obm.geriatr.1904086

Abstract: Background: As the world’s population ages, so the number of old and frail people increases. Respiratory disease is a common reason for hospital admission for older people. Aspiration of saliva, which is probably infected, is the likely etiological agent. The presence of an abnormal swallow has been [...]

Open Access Research Article

Relationship between Brain Injury and Clinical Biomarkers in Hypoxic-Ischemic Newborn Piglets

Francisco J Alvarez, Antonia A. Alvarez, Hector Lafuente, Daniel Alonso-Alconada, Jose L. Blanco-Bruned, Francisco Santaolalla, Enrique Hilario
Received: June 24, 2019; Published: November 15, 2019; doi:10.21926/obm.neurobiol.1904045

Abstract: (1) Background: Newborn affected by hypoxic-ischemic brain injury can die and the survivors suffer neurodevelopmental handicaps. Biomarkers are needed to identify the severity of hypoxic-ischemic insult in order to early determine the rescue treatment. The aim of this study was to correlate the path [...]

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Advances in Chemical Research

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