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Special Issue

Stem Cell Therapy

Submission Deadline: December 30, 2018 (Open)               Submit Now

Guest Editor

Luis Martinez, MD
President and CEO, Regenera Global, San Juan, 00926, Puerto Rico
E-Mail: [email protected]
Research Interests: stem cell; cancer; regenerative medicine and cell therapy; preventive medicine; clinical research

About This Topic

Dear Colleagues:

The field of stem cell medicine is advancing at a rapid pace. Interestingly, this advancement has been, to a point, fueled by parallel pathways. On one end, point of care stem cell treatments offered in clinics, and under generally lax regulatory guidelines have served to provide much empirical data on the safety and possible applications of autologous stem cell treatments. On the other end, academic institutions, alongside pharmaceutical and biotech companies, have focused on studying the complex stem cell environment. The intention being the development of stem cell biological drugs that abide by the traditional regulatory channels and which utilize placebo controlled studies to demonstrate efficacy. Independently, these pathways are, more and more, converging on a compromise between obtaining robust data, and facilitating the regulatory process. The point is to accelerate patient access to these novel therapies.

If we look at aging as a failure of stem cells, then chronic degenerative diseases arise from our bodies inability to maintain proper repair mechanisms at the cellular level. With this in mind, this special issue will focus on the translational and current clinical applications of stem cell therapies as they relate to treating, stopping, or reversing the aging process and its complications.

We invite articles that contemplate, but are not limited to the following topics:

  • Impact and modulation of telomere length on stem cell function and regenerative capacity
  • The use of stem cells to treat frailty and aging
  • Autologous vs. allogeneic stem cells for chronic degenerative diseases
  • Stem cell dosing and administration routes
  • Current approvals and coming of age indications for stem cells in medicine
  • Mitochondrial function in stem cells and aging

Planned Papers

Title: Stem cell therapy as alternative to reduce neuroinflammation
Authors: Braulio Fernandes de Carvalho, Paula Andrea Sampaio de Vasconcelos Carvalho, Ingridi de Souza Sene, Sérgio Emílio dos Santos Valente
Summary: This manuscript discusses about the use of neural stem cells and other cell types, from different sources, to fight neuroinflammation, as an alternative or alongside with drugs. Neuroinflammation is a key factor in several diseases and injuries of the nervous system.


Original Research

The Effect of the Human Plasma Molecule GHK-Cu on Stem Cell Actions and Expression of Relevant Genes

Loren Pickart, Anna Margolina
Received: June 8, 2018; Published: August 16, 2018; doi:10.21926/obm.geriatr.1803009