Preclinical Investigation of the Acute Effects of Trigonella foenum-graecum Seed Powder on Blood Glucose in Normal and Alloxan-Induced Diabetic Rabbits
Abstract
(ISSN 2573-4393)
OBM Integrative and Complementary Medicine is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. It covers all evidence-based scientific studies on integrative, alternative and complementary approaches to improving health and wellness.
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Special Issue
Herbal Medicines for the Treatment of Metabolic Syndrome
Submission Deadline: December 31, 2019 (Closed) Submit Now
Guest Editor
Srinivas Nammi, PhD
1. School of Science and Health, Western Sydney University, Penrith, Australia
2. National Institute of Complementary Medicine (NICM), Western Sydney University, Penrith, Australia
Research Interests: chronic kidney disease; fatty liver disease; herbal pharmacology; insulin resistance; lipid disorders; metabolic syndrome; obesity; pharmacokinetics and drug interactions; type 2 diabetes and its complications
About This Topic
Metabolic syndrome is posed as a significant health burden around the world and is a major high‐risk factor of type 2 diabetes. It is described as a pre-diabetic condition that includes obesity, dyslipidemia, impaired fasting glucose and/or impaired glucose tolerance, and reduced insulin sensitivity. The development of metabolic syndrome is influenced by a combination of genetic and environmental factors. The modern lifestyle of increased intake of high-calorie cafeteria fast food associated with decreased energy expenditure is among the environmental factors that contribute to the pandemic of metabolic syndrome. To reduce the constellation of events of hyperglycemia and hyperlipidemia, a multi-targeted approach controlling both glucose and lipid metabolism is needed. The currently available therapeutic options such as exercise, dietary modification, or a combination of synthetic anti‐diabetic, and anti-hyperlipidemic drugs possess their own limitations and a multitude of undesirable side effects. Hence, there is an increased demand to search and evaluate traditional approaches for the treatment of metabolic disorders, particularly the use of herbal medicines. Recently, there has been a resurgence of interest in the use of herbal medicines because of their reduced side effects compared to synthetic drugs. Thus, herbal medicines may represent future hope for the pharmacological management of metabolic syndrome firstly, as an important source of new lead molecules for the development of future single molecule-based synthetic drugs, and secondly as single- or multi-herbal formulae due to their multi-component, multi-targeted actions.
This special issue is dedicated to integrate the pharmacological actions and mechanisms of herbal preparations, extracts, isolated compounds, and semi-synthetic derivatives in the prevention and treatment of metabolic syndrome. We cordially invite researchers to contribute their original research articles and reviews on preclinical and clinical evaluation of herbal medicines in our special issue titled "Herbal Medicines for the Treatment of Metabolic Syndrome”
Potential topics include, but are not limited to:
Planned Papers
Title: The effects of Herbal medicines used with Jamaican women and their infants during pregnancy, postpartum and infancy
Authors: Dr. Jean Hannan: Affiliation: Florida International University/Jackson Memorial Hospital
Skye Nguyen: Florida International University
Faith Irving: Jackson Memorial Hospital
Oliver Fowler: Jackson Memorial Hospital
Donna Williams: Jackson Memorial Hospital
Title: The mechanistic view of Gymnema sylvestre herbal medicine of diabetes and obesity in yeast cells
Author: Govindsamy Vediyappan, PhD
Affiliations: Division of Biology, Kansas State University, Manhattan KS 66506, USA
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Welcome your submission!
Publication
Preclinical Investigation of the Acute Effects of Trigonella foenum-graecum Seed Powder on Blood Glucose in Normal and Alloxan-Induced Diabetic RabbitsAbstract To investigate the blood glucose lowering effect of the seed powder of T. foenum-graecum Linn (Papilionaceae) in normal and alloxan-induced diabetic rabbits. The blood glucose lowering effect of the seed powder was determined in normal and alloxan-induced (100 mg/kg, i.v.) diabetic rabbits, after oral administration of doses of 50, 100 and [...] |
Ashitaba (Angelica keiskei) Exerts Possible Beneficial Effects on Metabolic SyndromeAbstract Metabolic syndrome is a serious health condition comprising a combination of glucose metabolism disorder, high blood pressure and obesity. The main underlying risk factors for metabolic syndrome are abdominal obesity and insulin resistance. Various studies have shown that herbal medicines can be effective against these aspects of metabolic [...] |
Fructose Increases Uric Acid Contributing to Metabolic Syndrome - Herbal, Nutritional and Dietary Strategies to Reduce Uric AcidAbstract The metabolism of fructose by the liver produces uric acid and elevated serum uric acid levels is an independent risk factor for hypertension, metabolic syndrome, and cardiovascular disease. Fructose occurs in fruits and fruit juices, honey and in the sweeteners sucrose (common white sugar) and High Fructose Corn Syrup. Dietary fructose ma [...] |
Potentially Beneficial Effects of St. John’s Wort (Hypericum perforatum) in Patients with Metabolic SyndromeAbstract St. John’s wort (SJW), or Hypericum perforatum, is a perennial herb that is used for the treatment of depression in several countries. However, its effects in other common conditions, such as the metabolic syndrome, have not been elucidated. Some studies have investigated the effects of SJW extract on differentiation of adipocytes, inflammat [...] |
Thai Ethnomedicinal Plants Used for Diabetes Treatmentby
Methee Phumthum
and
Henrik Balslev
Abstract (1) Background: Diabetes is a metabolic disorder and a serious global health problem. Over 400 million people suffer from diabetes and it is estimated that the number will dramatically increase in the future. The cost of diabetes treatment for a single patient is very high. However, traditional knowledge could support poor patients for their [...] |
Dietary Supplements in Dyslipidemiaby
Emily Gutierrez
and
Yousef Elyaman
Abstract Lifestyle and dietary interventions can have a significant impact on patients with dyslipidemia and should be encouraged with the use of dietary supplements. With new research, there is evidence that using dietary supplements, specifically nutraceuticals can be helpful for cholesterol management. Four commonly used supplements are: Red Yeast [...] |
Obesity and Non-Alcoholic Fatty Liver - Therapies in Ayurvedic MedicinesAbstract Ayurveda is an ancient Indian medicinal practice. The present review includes translational research characterizing obesity, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
We reviewed published research on improving function through Ayurvedic medicine by searching electronic databases (Medline, Embase [...] |
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