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Special Issue

Herbal Medicines for the Treatment of Metabolic Syndrome

Submission Deadline: November 30, 2018(Open)               Submit Now      Flyer

Guest Editor

Srinivas Nammi, PhD
1. School of Science and Health, Western Sydney University, Penrith, Australia
2. National Institute of Complementary Medicine (NICM), Western Sydney University, Penrith, Australia
E-mails: [email protected]
Research Interests: chronic kidney disease; fatty liver disease; herbal pharmacology; insulin resistance; lipid disorders; metabolic syndrome; obesity; pharmacokinetics and drug interactions; type 2 diabetes and its complications

About This Topic

Metabolic syndrome is posed as a significant health burden around the world and is a major high‐risk factor of type 2 diabetes. It is described as a pre-diabetic condition that includes obesity, dyslipidemia, impaired fasting glucose and/or impaired glucose tolerance, and reduced insulin sensitivity. The development of metabolic syndrome is influenced by a combination of genetic and environmental factors. The modern lifestyle of increased intake of high-calorie cafeteria fast food associated with decreased energy expenditure is among the environmental factors that contribute to the pandemic of metabolic syndrome. To reduce the constellation of events of hyperglycemia and hyperlipidemia, a multi-targeted approach controlling both glucose and lipid metabolism is needed. The currently available therapeutic options such as exercise, dietary modification, or a combination of synthetic anti‐diabetic, and anti-hyperlipidemic drugs possess their own limitations and a multitude of undesirable side effects. Hence, there is an increased demand to search and evaluate traditional approaches for the treatment of metabolic disorders, particularly the use of herbal medicines. Recently, there has been a resurgence of interest in the use of herbal medicines because of their reduced side effects compared to synthetic drugs. Thus, herbal medicines may represent future hope for the pharmacological management of metabolic syndrome firstly, as an important source of new lead molecules for the development of future single molecule-based synthetic drugs, and secondly as single- or multi-herbal formulae due to their multi-component, multi-targeted actions.

This special issue is dedicated to integrate the pharmacological actions and mechanisms of herbal preparations, extracts, isolated compounds, and semi-synthetic derivatives in the prevention and treatment of metabolic syndrome. We cordially invite researchers to contribute their original research articles and reviews on preclinical and clinical evaluation of herbal medicines in our special issue titled "Herbal Medicines for the Treatment of Metabolic Syndrome”

Potential topics include, but are not limited to:

  • Preclinical studies on anti-obesity and antidiabetic potential of herbal extracts/compounds
  • Effects of herbal medicines on endocrine pharmacology, metabolic syndrome and obesity
  • Herbal medicines diabetic complications and non-alcoholic fatty liver disease
  • Role of herbal medicines in ameliorating oxidative stress and inflammatory conditions associated with obesity, metabolic syndrome, and type 2 diabetes
  • Clinical trials/reports on the efficacy of herbal medicines for the prevention/treatment of obesity, metabolic syndrome, and type 2 diabetes
  • Safety evaluation of known anti-obesity and antidiabetic herbs
  • Standardization of herbal preparations used in ameliorating metabolic diseases
  • Bioavailability and pharmacokinetic of herbal medicines used in ameliorating metabolic diseases

Planned Papers

Title: The effects of Herbal medicines used with Jamaican women and their infants during pregnancy, postpartum and infancy
Authors: Dr. Jean Hannan: Affiliation: Florida International University/Jackson Memorial Hospital
Skye Nguyen: Florida International University
Faith Irving: Jackson Memorial Hospital
Oliver Fowler: Jackson Memorial Hospital
Donna Williams: Jackson Memorial Hospital

Title: The mechanistic view of Gymnema sylvestre herbal medicine of diabetes and obesity in yeast cells
Author: Govindsamy Vediyappan, PhD
Affiliations: Division of Biology, Kansas State University, Manhattan KS 66506, USA



Ashitaba (Angelica keiskei) Exerts Possible Beneficial Effects on Metabolic Syndrome

Naoki Ohkura, Gen-ichi Atsumi, Seima Uehara, Mitsuhiro Ohta, Masahiko Taniguchi
Received: July 18, 2018; Published: January 23, 2019; doi:10.21926/obm.icm.1901005


Potentially Beneficial Effects of St. John’s Wort (Hypericum perforatum) in Patients with Metabolic Syndrome

Hideya Mizuno, Ayako Taketomi, Toshikatsu Nakabayashi
Received: June 27, 2018; Published: September 28, 2018; doi:10.21926/obm.icm.1803021

Original Research

Thai Ethnomedicinal Plants Used for Diabetes Treatment

Methee Phumthum, Henrik Balslev
Received: April 25, 2018; Published: September 25, 2018; doi:10.21926/obm.icm.1803020

Case Report

Dietary Supplements in Dyslipidemia

Emily Gutierrez, Yousef Elyaman
Received: March 4, 2018; Published: May 24, 2018; doi:10.21926/obm.icm.1802008


Obesity and Non-Alcoholic Fatty Liver - Therapies in Ayurvedic Medicines

Samskruthi Menashi, B.Eng, Lawrence B Cohen, M.D, Manuela G. Neuman, Ph.D
Received: February 10, 2018; Published: March 29, 2018; doi:10.21926/obm.icm.1801002