Table of Contents

Volume 1,Issue 2

Open Access Review

Perspective on Neurobiological and Clinical Early Indicators of Mild Cognitive Decline and Alzheimer’s Disease

Received: 17 April 2017;  Published: 09 July 2017;  doi: 10.21926/obm.neurobiol.1702006

Abstract

There is a need for early diagnosis, monitoring and treatment of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI). Traditional assessments of cognitive decline have been found to lack sensitivity and accuracy in differentiating varying stages of Demetria and cognitive decline as well as [...]

Open Access Review

Perspectives on the Role of Endocannabinoids in Autism Spectrum Disorders

Received: 11 April 2017;  Published: 27 April 2017;  doi: 10.21926/obm.neurobiol.1702005

Abstract

Autism spectrum disorders (ASDs) are diagnosed on the basis of three behavioral features, namely, (1) deficits in social communication, (2) absence or delay in language and (3) stereotypy. The consensus regarding the neurological pathogenesis of ASDs is aberrant synaptogenesis and synapse function. [...]

Open Access Review

A Neurodevelopmental Perspective for Autism-Associated Gene Function

Received: 10 April 2017;  Published: 24 April 2017;  doi: 10.21926/obm.neurobiol.1702004

Abstract

Large-scale genetic sequencing studies have identified a wealth of genes in which mutations are associated with autism spectrum disorder (ASD). Understanding the biological function of these genes will shed light onto the neurodevelopmental basis of ASD. Here, we defined functional categories repr [...]

Open Access Perspective

Neurobiology of Sleep and Microbiomics in Aging

Received: 22 February 2019;  Published: 12 April 2017;  doi: 10.21926/obm.neurobiol.1702003

Abstract

(1) Background: The daily rhythms of life on earth are governed by a central clock located in the hypothalamus and entrained primarily by light. By virtue of its connections to a myriad of other clocks located both in the brain and in peripheral organs and cells, this clock provides a timing signal [...]

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