Clinical Tolerance Trials in Renal Transplantation – Where Do We Stand?


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Open Access
ISSN 2577-5820
© 2019 by the authors; CC BY 4.0 licence
OBM Transplantation , Volume 3 , Issue 2 (2019)
Pages: 205
Published: November 2019
(This book is a printed edition that was published in OBM Transplantation)
Cover story: Alpha cells within human islets actively secrete the prosurvival peptide GLP-1. Treatment of human islets with the DPP4 inhibitor sitagliptin resulted in elevated levels in the active form of GLP-1. This increase in active GLP-1 may enhance protection from islet cell death and pre-treatment of islets with DPP4 inhibitors prior to transplantation has the potential to improve post-transplant islet survival. View this paper.
Volume 3,Issue 2
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