OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.
We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor.
Indexing: DOAJ-Directory of Open Access Journals.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 6 days from acceptance to publication (median values for papers published in this journal in the first half of 2020, 1-2 days of FREE language polishing time is also included in this period). A first decision provided to authors of manuscripts submitted to this journal are approximately 3.7 weeks (median values) after submission.
Islet Cell Transplantation
Submission Deadline: January 15, 2021 (Open) Submit Now
Kenneth L. Brayman, MD, PhD, FACS
Professor of Surgery, Medicine and Biomedical Engineering, Director, Kidney, Pancreas and Islet Transplant Programs, Director, Center for Cellular Therapy and Biologic Theraputics, Department of Surgery, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA 22908, USA
Research Interests: Transplant immunosuppression; chronic allograft nephropathy; solid organ transplantation in patients with HIV; islet cell transplantation; transplantation tolerance; gene therapy and xenotransplantation; kidney transplantation; pancreas transplantationa
Preeti Chhabra, PhD
Department of Surgery, University of Virginia, Charlottesville, VA 22908, USA
Research Interests: Type 1 diabetes; islet transplantation; inflammatory diseases; transplant immunosuppression; tolerance induction; regenerative medicine and immunoglobulin M therapy
About This Topic
This special issue primarily focuses on beta-cell replacement beyond islets alone, including isolated beta-cells, stem cells, encapsulated cells and xenotransplants. It covers all evidence-based preclinical and clinical research related to islet transplantation, i.e. transplantation procedures; graft survival and prevention of graft dysfunction and failure caused due to immune rejection and the recurrence of autoimmunity; the harmful side-effects of chronic immunosuppression; novel autoimmune and β-cell therapies that restore immune regulation and restore glucose control following islet transplantation; as well as financial and regulatory approval issues. It also invites articles on regeneration of functional insulin-producing beta cells for transplantation; encapsulation or immunoisolation of alternative beta-cell sources; and predictive or prognostic biomarkers that provide surrogate end points to determine the efficacy of islet transplantation. Last but not least, articles in the field of islet xenotransplantation are also invited.
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