OBM Transplantation

(ISSN 2577-5820)

OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.

OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.

We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor. 

Indexing: DOAJ-Directory of Open Access Journals.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 6 days from acceptance to publication (median values for papers published in this journal in the first half of 2020, 1-2 days of FREE language polishing time is also included in this period). A first decision provided to authors of manuscripts submitted to this journal are approximately 3.7 weeks (median values) after submission.

Current Issue: 2020  Archive: 2019 2018 2017

Special Issue

Isolation and Characterization of Adult Therapeutic Cells

Submission Deadline: June 30, 2019 (Open) Submit Now

Guest Editors

Robert C. McCarthy

President, VitaCyte LLC, 1341 Sadlier Circle West Drive, Indianapolis, IN 46239, USA
Tel: 317-450-6647
Fax: 317-917-3459

Website | E-Mail

Research Interests: Biotechnology; Cell Biology; Molecular Biology; Bioengineering

Stuart K. Williams II, Ph.D.

Professor, Cardiovascular Innovation Institute, Jewish Hospital and University of Louisville, Louisville, KY 40202, United States; Department of Physiology and Biophysics, Jewish Hospital and University of Louisville, Louisville, KY 40202, United States
Office: (502) 852-1379

Website | E-Mail

Research Interests: (1) Cardiovascular Biomedical Engineering: Regenerative Medicine/Tissue Engineering, Stents and Stent Grafts, Adult Stem Cell Transplantation, Angiomics - Microarrays, Genomics and Proteomics, Shear Effects on Cells, Restenosis, Angiogenesis, Gene Therapy; (2) Biomaterials: Biomedical Implant Design, Direct –Write Printing – Biomimetics, Surface, Modification and Characterization, Soft Tissue Replacement, Cell Migration, Anti-Infective Coatings; (3) Diabetes Mellitus: Non Enzymatic Glycation, Capillary Permeability and Angiopathies, Islet Cell Transplantation

About This Topic

The increasing interest in using adult cells to develop cell therapeutics for management of patients with many different clinical conditions is at the forefront of medical treatment. These publications focus primarily on clinical outcomes with cursory attention paid to the preparation and characterization of the therapeutic cells used in the treatment. This issue focuses on key criteria to consider when isolating islets, hepatocytes, and mesenchymal stem cells from tissue for therapeutic use. The issue addressed for many of these cell types are the identification of critical process parameters in the cell isolation process; the impact of cell enrichment steps on functional activity; markers used to characterize the therapeutic cell population; and lastly status of potency assays required for releasing cells before transplant. If you are interested in submitting an article for inclusion in this special issue, please contact one of the guest editors.

Publication

Open Access Research Article

A Computational Simulation Technology for Specific Counting of Perinatal and Postnatal Human Tissue Stem Cells for Transplantation Medicine

Received: 22 April 2020;  Published: 28 August 2020;  doi: 10.21926/obm.transplant.2003117

Abstract

Although tissue stem cells are essential for the maintenance, renewal, and repair of vertebrate organs and tissues, previously, the simple act of counting them has not been possible. For more than a half-century, progress in tissue stem cell research and medicine has been undermined by the lack of a [...]
Open Access Review

Birth Tissue-Derived Mesenchymal Stromal/Stem Cell Isolation and Assessment

Received: 25 September 2019;  Published: 09 June 2020;  doi: 10.21926/obm.transplant.2002112

Abstract

Mesenchymal Stromal/Stem Cells (MSCs) were originally discovered in the 1970s. MSCs are considered a multipotent population that retain tri-lineage differentiation. These cells can be sourced from a variety of tissues, including bone marrow, adipose, molar pulp, and birth tissues. Historically varyi [...]
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