OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes research articles, technical reports and invited topical reviews. Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 7.6 days from acceptance to publication (median values for papers published in this journal in 2020, 1-2 days of FREE language polishing time is also included in this period).

Current Issue: 2021  Archive: 2020 2019 2018 2017

Special Issue

Quantum Brain Dynamics

Submission Deadline: June 15, 2020 (Open) Submit Now

Guest Editor

Raul Valverde, PhD PEng


About This Topic

Quantum brain dynamics (QBD) is a group of hypothesis which explains the function of the brain within the framework of quantum field theory. It posits that quantum mechanical phenomena, such as quantum entanglement and superposition, may play an important part in the brain's function and could form the basis for an explanation of consciousness. Quantum brain dynamics is originated in the 1960s by the great theoretical physicist, Hiroomi Umezawa. Both quantum physics for sub-microscopic constituents of brain cells and tissues, and classical physics for the microscopic and macroscopic constituents, are simultaneously justified by this theory. It poses an alternative to the dominant conceptions in the neuro- and cognitive sciences, which take neurons organized into networks as the basic constituents of the brain. Certain physical substrates in the brain are shown to support quantum field phenomena, and the resulting strange quantum properties are used to explain consciousness and memory. The whole of memory is stored in such a state of macroscopic order and consciousness is realized by the creation and annihilation dynamics of energy quanta of the electromagnetic field and molecular fields of water and protein. In addition, many neural processes related to quantum states. In this special issue, we welcome any papers that show new view, conception, inventive and original approaches in quantum brain dynamics. Original research reports, review articles, communications, and perspectives are welcome in all areas pertinent to this topic. All accepted papers will be published free of charge.


Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. Guidelines for authors and other relevant information for submission of manuscripts are available on the Instructions for Authors page. OBM Neurobiology is an international peer-reviewed Open Access monthly journal published by LIDSEN. Please visit the Instructions for Authors page before submitting a manuscript.

Planned Papers

Title: Long term potentiation and memory in a quantum-like neuromorphic model
Author: Stephen Selesnick
Affiliation: University of Missouri, St. Louis
Abstract: In earlier work we developed a quantum-like neuromorphic network model that employs a mixture of physical and computational paradigms. This model can take into account non-synaptic modes of connection. Here we use it to derive a number of interesting properties of memory systems. We derive a computational version of the phenomenon of \emph{early long term potentiation} within the model, which mathematically supports the Hebbian hypothesis. Such computations `in memory' are of interest in the pursuit of artificial intelligence by means of neuromorphic hardware such as memristor-like circuits. We also investigate the retrieval mechanism inherent in the model and in light of it we briefly examine two other memory associated phenomena derivable within the model, namely pattern completion and Tsien's power-of-two wiring law

Title: Quantum theory of EEG with application to single trial ERP analysis
Authors: D. Melkonian and A. Harris.
Affiliation: Faculty of Medicine and Health, University of Sydney, Sydney, Australia

Title: Nonlinear dynamics and chaotic trajectories in brain-mind visual experiences
Authors: Tania Re 1, Giuseppe Vitiello 2
1. UNESCO Chair "Anthropology of Health. Biosphere and Healing System", University of Genoa, Genoa, Italy and Referring Center for Phytotherapy, Tuscany Region, Careggi University Hospital, Florence, Italy
2. Physics Department "E.R. Caianiello", University of Salerno, 84084 Fisciano (Salerno), Italy
Abstract: We discuss brain visual experiences made in conditions of low degree of openness of brain on the environment, for example during dreaming, or in meditation, or under the effects of psychoactive substances, in coma states, or other reduced sensory perception states, etc. For brevity we refer to them as to brain-mind visual experiences, meaning that such a visual activity is not the one connected to the actual seeing as in the awake state. In the dissipative quantum model of brain, the criticality of the dynamics is enhanced in brain low openness states and it is at origin of movie-like sequences of images in visual experiences. These sequences and abrupt shifts from one image pattern to another are described by chaotic trajectories through the memory space. Truthfulness and realism felt in visual experiences are discussed in terms of the algebra of the doubling of the degrees of freedom in the dissipative model. In our discussion we consider few aspects of visual experiences made by a subject during an Amazonian Ayahuasca ceremony.

Title: Environmental signal-feedback mechanisms shaping neuronal somatic cell nuclear recombination via state reduction of nucleoprotein superpositions
Authors: William Brown 1, Nassim Haramein 2 and Olivier Alirol 2
Affiliation: 1 Molecular Biologist, 2 Physicists, Resonance Science Foundation and Torus Tech LLC., California, USA

Title: Quantum Theory of EEG with Application to the Single-trial ERP Analysis
Author: Dmitriy Melkonian
Abstract: Probabilistic formalism of quantum mechanics is used to quantitatively link the electroencephalogram (EEG) with the underlying microscale activity of cortical neurons. Previous approaches implemented methods of classic physics to reconstruct the EEG in terms of explicit physical models of cortical neurons and the volume conductor. However, the multiplicity of cellular processes with extremely intricate mixtures of deterministic and random factors prevented creation of consistent biophysical parameter sets. To avoid uncertainty surrounding physical attributes of the neuronal ensembles, we undertake here a radical departure from deterministic equations of classical physics to the probabilistic reasoning of quantum mechanics. Crucial step includes the relocation of the elementary bioelectric sources from the cellular to molecular level. Using novel method of the time-frequency analysis with adaptive segmentation for digital processing of empirical EEG and single trial event related potentials (ERPs), we found universal “building blocks” of these cortical processes both in the frequency and time domains. This result is qualified as a phenomenon known in statistical physics and quantum mechanics as universality. The rationale is that despite dramatic differences in the cellular machineries, the probabilistic factors governed by the central limit theorem produce the ECG waveform as a statistical aggregate of the synchronized activities of large ensembles of closely located cortical neurons. Using these theoretical and empirical findings, the probabilistic laws governing the microscale machinery underlying the EEG genesis are deduced.


Open Access Original Research

Quantum Theory of EEG with Application to the Single-Trial ERP Analysis

Received: 17 July 2020;  Published: 27 January 2021;  doi: 10.21926/obm.neurobiol.2101084


The probabilistic formalism of quantum mechanics is used to quantitatively link the electroencephalogram (EEG) with the underlying microscale activity of cortical neurons. Previous approaches applied methods of classic physics to reconstruct the EEG&l [...]
Open Access Research Article

Transcriptome Signatures of Dysregulated Brain Dynamics Induce Entangled Network States.

Received: 15 June 2020;  Published: 30 December 2020;  doi: 10.21926/obm.neurobiol.2004077


Marks of brain disorders may be visible through abnormal networks characterized by states with distinct signatures or connectivity patterns. Apart from neurodegenerations, drug abuse or eventually addiction may exert complex perturbative effects over human health, including damage to various organs [...]
Open Access Research Article

Non-linear Dynamics and Chaotic Trajectories in Brain-Mind Visual Experiences during Dreams, Meditation, and Non-Ordinary Brain Activity States

Received: 30 April 2020;  Published: 11 June 2020;  doi: 10.21926/obm.neurobiol.2002061


The present report discusses brain visual experiences in conditions of low degree of openness of the brain toward the environment, for example, while dreaming, during meditation, or in non-ordinary brain activity states such as under the effects of psychoactive substances, in the state of coma, or i [...]