(ISSN 2577-5820)
OBM Transplantation (ISSN 2577-5820) is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc., which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.
The journal publishes all types of articles in English. There is no restriction on the length of the papers. We encourage authors to be concise but present their results in as much detail as necessary, as reviewers are expected to emphasize scientific rigor and reproducibility.
Publication Speed (median values for papers published in 2023): Submission to First Decision: 6.7 weeks; Submission to Acceptance: 14.4 weeks; Acceptance to Publication: 6 days (1-2 days of FREE language polishing included)
Special Issue
Diagnosis and Management of Infections in Solid Organ Transplant Recipients
Submission Deadline: October 30, 2018 (Closed) Submit Now
Guest Editor
Maricar Malinis, MD FACP, FIDSA
Assistant Professor of Medicine and Surgery (Transplant), Medical Director, Transplant Infectious Diseases, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA;
Department of Surgery (Transplant), Yale School of Medicine, New Haven, CT, USA
Tel.: 203 785 3561
Research Interests: Aging; Cytomegalovirus; Fungi; HIV; Transplantation; Immunocompromised host; Transplant infectious diseases
About This Topic
Solid organ transplantation is an established life -saving therapy for end-organ diseases of the kidney, liver, heart, and lungs. The improved patient and graft survivals have been attributed to advancements in surgical techniques and effective immunosuppressive therapies. However, immune suppression, pre-existing co-morbidities, and potential surgical complications can result in infectious complications after organ transplantation. In this particular issue of OBM transplantation, solicited articles will focus on review of current approaches to the diagnosis and management of post-transplant infections in solid organ transplant recipients due to bacterial, viral and fungal pathogens. Each article will also address strategies of screening and prevention of post-transplant infections.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (transplantation@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
Publication
Endemic Mycoses and Cryptococcus in Solid Organ Transplant RecipientsAbstract The endemic mycoses are an important cause of morbidity and mortality in transplant recipients. These fungal infections are notable for a dimorphic life cycle, a specific geographic distribution, and typical infection via environmental exposure. Their nonspecific presentation, often mimicking other infections, can make diagnosis challenging [...] |
Non-CMV Viral Infections Following Solid-Organ Transplantation – Focus on Human T-Cell Lymphotropic Virus Type-1 and Human Herpesviruses-6,-7 and -8Abstract In non-endemic areas, HTLV-1 is an uncommon pathogen in the transplant host but can be associated with significant morbidity and mortality. Careful assessment of risk factors, targeted screening and heightened awareness of the clinical presentation of HTLV-1 associated disease is necessary for timely recognition and management in the transplan [...] |
Respiratory Viral Infections in Lung Transplant Recipients: Implications for Long Term Outcomes and Emerging TherapiesAbstract Lung transplant recipients are at greater risk of respiratory viral infections as compared to other solid organ transplant recipients due to constant exposure of the allograft to the external environment. There are no standardized methods for surveillance, prevention, or treatment of these infections despite their association with increased [...] |
Secondary Antibody Deficiency in a Heart Recipient with Systemic AspergillosisAbstract Secondary antibody deficiency has been associated with risk of invasive fungal infections in solid organ transplantation. Single center, multicenter and metanalysis studies have tested this association. Therapy of these infectious complications in the presence of a secondary antibody deficiency after transplantation remain a challenge for [...] |
Role of Procalcitonin in Management of Infection in Solid Organ Transplantation Recipients: ReviewAbstract Infections are a common cause of morbidity and mortality in solid organ transplantation (SOT) recipients. Procalcitonin (PCT) has garnered attention as an inflammatory marker that has been shown to be a valuable marker for early identification of systemic bacterial infection. However, interpretation of PCTs value in the different types of [...] |
New Frontiers in Solid Organ Transplantation from Donors with Human Immunodeficiency Virus, Hepatitis C Virus Infection, and Multidrug Resistant Organismsby
Jessica Lum
and
Sherif B. Mossad
Abstract Despite the advances that have been made in the field of solid organ transplantation (SOT), organ shortage remains a persistent problem and continues to worsen. In addition, the donor pool has been changing with the increase in drug overdose deaths each year with the ongoing opioid epidemic More donors are meeting the 2013 U.S. Public Health [...] |
Tuberculosis Screening and Treatment in Solid Organ TransplantationAbstract Background: Tuberculosis (TB) is a common infection with challenges in diagnosis and treatment. Management of TB in solid organ transplant (SOT) candidates and recipients poses unique challenges not seen in other populations.
Questions and recommendations: Latent TB infection (LTBI) is important to diagnose pre-transplant through history, [...] |
Challenges in Diagnosis and Management of Nontuberculous Mycobacteria in Solid Organ TransplantationAbstract Non-tuberculous mycobacteria (NTM) infections are relatively rare but carry significant morbidity in solid organ transplant (SOT) recipients. Given the rarity of disease and diagnostic limitations, a high index of suspicion is required for accurate diagnosis and initiation of appropriate treatment. We discuss the challenges in diagnosis and [...] |
Solid Organ Transplantation in Older Adults. Infectious and Other Age-Related ConsiderationsAbstract In the U.S., older adults aged 65 or above comprise nearly one quarter of the solid organ transplant (SOT) waitlists, and the number of transplants performed in this age group continues to increase. There are no specific guidelines for the assessment and follow up of the aged SOT candidate or recipient. Older adults are at increased risk of [...] |
Isolated Hepatic Mucormycosis in the Early Post-Transplant Period: A Case Report and Literature ReviewAbstract Mucormycosis is a rare fungal infection associated with high morbidity and mortality that typically afflicts immunocompromised hosts. We present a case of isolated hepatic mucormycosis that developed in the early post-transplant period. Initial presentation was concerning for allograft rejection, but definitive diagnosis was made with histopat [...] |
Parvovirus B19 Infection in Solid Organ Transplantation: Report of A Case and A ReviewAbstract Infection with parvovirus B19 is common, with up to 55% of adults showing seropositive evidence of prior infection. Clinical disease can occur due to acute infection, secondary infection, or reactivation. The clinical presentation of primary infection depends on age, the presence of a hematologic condition, and immune status. It is an uncom [...] |
Chagas Disease, Leishmaniasis, and Malaria in Solid Organ Transplant Recipientsby
Spinello Antinori
and
Laura Milazzo
Abstract Solid organ transplantation (SOT) is increasingly employed worldwide to treat several diseases causing either acute and chronic organ failure. Recipients of SOT are at increased risk to develop infections as a consequence of immunosuppressive therapy. Sometimes such infections may be acquired by the transplanted organ or by reactivation of [...] |
A Tale of Two Flaviviruses: West Nile Virus and Zika Virus in Solid Organ TransplantationAbstract Flaviviruses can cause epidemics and endemics with substantial public health threat and economic impacts. In the last few decades, many flaviviruses have re-emerged or expanded their territories to new regions or continents, including West Nile virus that has become endemic in the US since its arrival in 1999 and Zika virus that recently sprea [...] |
An Approach to Fungal Diagnostics in Solid Organ Transplantationby
David C. Gaston
and
Marwan M. Azar
Abstract The approach to diagnosing fungal infections following solid organ transplantation (SOT) is patient-specific. An assessment of an individual’s risk for particular infections, also understood as the pre-test probability, should guide appropriate diagnostic testing whereas diagnostic stewardship is needed to produce interpretable, actionable [...] |
Strongyloidiasis in Solid Organ Transplantationby
Ashrit Multani
and
Stanley Deresinski
Abstract Strongyloides stercoralis, an intestinal parasitic nematode (roundworm), infects more than 100 million people worldwide. While most infected immunocompetent persons are either asymptomatic or experience only mild, intermittent symptoms, immunosuppressed individuals, including those undergoing solid organ transplantation, are at increased risk [...] |
The Impact of Allograft CXCL9 during Respiratory Infection on the Risk of Chronic Lung Allograft Dysfunctionby
Michael Y. Shino
,
Ariss Derhovanessian
,
David M. Sayah
,
Rajan Saggar
,
Ying Ying Xue
,
Abbas Ardehali
,
Barry R. Stripp
,
David J. Ross
,
Joseph P. Lynch
,
Robert M. Elashoff
,
S. Samuel Weigt
and
John A. Belperio
Abstract The long term clinical significance of respiratory infections after lung transplantation remains uncertain. In this retrospective single-center cohort study of 441 lung transplant recipients, we formally evaluate the association between respiratory infection and chronic lung allograft dysfunction (CLAD). We furthermore hypothesized that bronch [...] |
| 2023 |  |
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| CiteScore | SJR | SNIP |
| 0.6 | 0.179 | 0.17 |
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Vidhi is a Clinical yoga therapist; mentor for yoga therapy training in Krishnamacharya tradition. She holds a MSc in Public health from Kings College London.
Mirela Olympia Fagarasan Palmer
Luigi Fontana, MD, PhD.jpg)
Zhong-Ting (Justin) is a PhD student from Nanyang Technological University (Singapore). He holds BSc in Applied Chemistry and MSc in Environmental Engineering. He was a R&D researcher of NanoMaterials Technology Pte Ltd in Singapore (2006-2012). His current research interests are functional nanomaterials synthesis & design, and their application into environmental/chemical engineering. He has published near 60 SCI papers in Applied Catalysis B, Chemical Engineering Journal and so on with H-Index 23. He also serviced as reviewers over 40 Journals such as Appl. Catal. B, Water Research, Chem. Eng. J, ACS Applied Materials & Interface, etc. He was honored such as “The Bsic Research Achievment 1st Award of CIESC”, “The ZJUT Fund Breeding Distinguished Young Scholars” etc.
Rolf Teschke studied Medicine in Munich and Marburg, where he finished his MD thesis before starting a residency at the Department of Pathology, University of Marburg. Subsequently and with a fellowship of the Deutsche Forschungsgmeinschaft, he worked at the Bronx VA Hospital/Mount Sinai Hospital in New York during 1972–1975 together with Professor Charles S. Lieber and successfully isolated MEOS and expanded its characterization. Back in Germany, he was at the Heinrich-Heine University in Düsseldorf with a focus on alcoholic liver disease, biochemical drug studies, and clinical intoxications by halogenated aliphatic hydrocarbons, where he became a Professor of Medicine. In 1987, he was offered a chief position and appointed as Director of the Medical Department II, City Hospital Hanau, Teaching Hospital of the Johann Wolfgang Goethe University Frankfurt/Main. His clinical and research interests are on liver injury by drugs and herbs including causality assessment by RUCAM in close association with Dr. Gaby Danan in Paris. A perfect cooperation exists also with Professor Tran Dang Xuan of the University of Hiroshima, Japan. Finally, he is the author of more than 275 publications including books and book chapters, and he is editor in chief of scientific journals and member of editorial boards.