Sumail Bhogal, Matthew Minn, Pranay Krishnan, Reena C. Jha
Received: February 18, 2019; Published: November 18, 2019; doi:10.21926/obm.transplant.1904092

Abstract: Objective: The purpose of this study was to evaluate the common locations of perihepatic fluid collections after liver transplantation, assess their complexity, and understand their natural history and clinical significance. Materials and Methods: A retrospective analysis of 189 postoperative ortho [...]

Jose A. Morillas, Sherif Beniameen Mossad
Received: October 24, 2019; Published: November 18, 2019; doi:10.21926/obm.transplant.1904091

Abstract: Toxoplasmosis in liver transplantation (LT) is uncommon, especially in the current era of universal prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) for Pneumocystis jirovecii pneumonia (PJP). Here we present a case of a 55-year-old woman LT recipient, on dapsone or PJP prophylaxis due to su [...]

David J. Ross, Abbas Ardehali, Christine Natori, John A. Belperio 
Received: September 19, 2019; Published: November 07, 2019; doi:10.21926/obm.transplant.1904090

Abstract: INTRODUCTION: TH-17 and IL-6 interactions and detrimental biologic effects have been shown in rodent models of Chronic Lung Allograft Dysfunction (CLAD). Similarly, these pathways have been found to be upregulated in human CLAD. Tocilizumab (TCZ), a humanized monoclonal antibody targets the IL-6 r [...]

Kyungmin Ko, Juan F. Guerra, David F. Garvin
Received: August 29, 2019; Published: October 28, 2019; doi:10.21926/obm.transplant.1904089

Abstract: Background: Graft site candidiasis is a serious complication after solid organ transplantation, often presenting as invasive arteritis leading to graft loss or even death. Case Report: We report a case of anastomotic site candidiasis leading to arterial rupture and death at postoperative day 10 with [...]

Renato Pol, Tiziana Ruggiero, Luisa Giaccone, Davide Camisassa, Andrea Spadafora, Giulia Rivetti, Marta Bezzi, Stefano Carossa
Received: June 14, 2019; Published: October 23, 2019; doi:10.21926/obm.transplant.1904088

Abstract: Objective Hematopoietic stem cell transplant has to be preceded by chemotherapy and radiotherapy. The following neutropenia and thrombocytopenia could be the cause of post transplant complications. Patient undergoing transplantation need to be eradicated of any possible infectious focus. Nowadays th [...]

Susanna Lam, Jerome M Laurence, Deborah J Verran
Received: July 01, 2019; Published: October 08, 2019; doi:10.21926/obm.transplant.1904087

Abstract: A range of corrective surgical procedures may be required in adult renal transplant recipients who sustain loss of integrity of the abdominal wall in the first month postoperatively. Where this involves the fascia, such as in acute fascial dehiscence or in renal allograft compartment syndrome, more [...]

Vanessa G. Oliveira, Filipa Saraiva, Fátima Costa, Aida Botelho de Sousa
Received: February 27, 2019; Published: September 23, 2019; doi:10.21926/obm.transplant.1903086

Abstract: Nowadays, hematopoietic stem cell transplantation (HSCT) is a common procedure in Hematology Units within Reference Centres, mainly for the treatment of hematological malignancies such as multiple myeloma, lymphoma and acute leukemia. Nevertheless, HSCT has much wider applications namely in autoimmu [...]

Anita Modi, Sherif Beniameen Mossad
Received: July 07, 2019; Published: September 06, 2019; doi:10.21926/obm.transplant.1903085

Abstract: Chronic inflammatory states lead to T cell exhaustion, characterized by reduced T cell proliferation and activity. Immune checkpoint inhibitors (ICPI) reactivate T cells to restore the immune system’s natural defenses against foreign antigens. The widespread use of these agents in the treatment of m [...]

Salim Hamdani, Daniel Azoulay
Received: April 18, 2019; Published: September 04, 2019; doi:10.21926/obm.transplant.1903084

Abstract: The privileged liver by its immunological status is described as a tolerogenic organ. However, these alone do not explain the installation of a tolerance after single or combined liver transplantation (kidney, heart, pancreas, intestine). Other factors appear to be involved in the identification of [...]

Qing Ye, Yijen L. Wu, Lesley M. Foley, Parker H. Mills, Fang-Cheng Yeh, Haosen Zhang, Danielle F. Eytan, Li Liu, T. Kevin Hitchens, Chien Ho
Received: January 07, 2019; Published: August 29, 2019; doi:10.21926/obm.transplant.1903083

Abstract: Background: Cardiac allograft vasculopathy (CAV) remains a major obstacle to long-term heart allograft survival. A number of studies show that immune mechanisms involved in CAV. Using non-invasive cellular MRI (CMRI) to explore indicators of CAV lesions and characterize its development could provi [...]