Advances in Environmental and Engineering Research (AEER) is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. This periodical is devoted to publishing high-quality peer-reviewed papers that describe the most significant and cutting-edge research in all areas of environmental science and engineering. Work at any scale, from molecular biology through to ecology, is welcomed.
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MicroRNA-Based Therapies for Ebola, HIV-1, and Zika Virus
Submission Deadline: May 01, 2022 (Open) Submit Now
Professor Omar Bagasra, MD, PhD
South Carolina Center for Biotechnology, Orangeburg, SC 29115, USA
Research Interests: Effects of Environment in Development of Autism; Prostate and Breast Cancers: Racial and cultural disparity; MicroRNA based therapies for Ebola, HIV-1, and Zika virus; Zika virus and microcephaly: What is causing small brain in the infected mothers' newborns? Forensic Sciences: Field drug testing, Forensic DNA fingerprinting
Professor Ewen McLean, PhD
Aqua Cognoscenti LLC, West Columbia, South Carolina 29170, USA
Research Interests: Animal Physiology; Animal Nutrition; Meat Quality; Feed Formulation; Animal Biotechnology; Meat Science; Aquaculture; Fisheries; Feed Evaluation; Animal Husbandry
About this Topic:
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate more than half of human protein-coding genes and play a pivotal role in cellular development, proliferation, organogenesis, metabolism, and homeostasis. The ability of these tiny ~22 double stranded miRNA molecules to regulate, not only endogenous gene expression, but also control exogenous agents like Ebola, HIV-1 and Zika virus is the focus of this special edition. We invite all interested investigators to contribute their work in the form of research articles, reviews, and opinions regarding the role of miRNAs in quelling these three major deadly diseases. We are particularly interested in studies that address the potential of using miRNAs that can subsequently lead to miRNA-based vaccines. Host miRNA expression can either promote or repress viral replications and understanding their expression and functions during Ebola, HIV-1 and Zika infections may provide critical insights to support development of miRNA-based therapeutics and vaccines that may act either as miRNA antagonists or miRNA mimics. We are also interested in contributions that address miRNA delivery systems, especially exosome-based therapies, that deliver therapeutic miRNAs to specific target cells.
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