Climate Change-Induced Stress and Neural Plasticity: Genetic and Epigenetic Mechanisms of Adaptation
Abstract
Climate Change-Induced Stress and Neural Plasticity: Genetic and Epigenetic Mechanisms of Adaptationby
Abstract Changes in the environment driven by climate change are becoming significant stressors that impact brain function, but the connections between these changes and neural plasticity remain unclear. This review aims to offer a comprehensive synthesis of the impact of climate-related stressors on neural plasticity via genetic and epigenetic mechanisms. A [...] |
Development of New Macroencapsulating Planar Devices to Inhibit Allorejection of Islet Transformed Cellsby
Abstract Subcutaneous transplantation of islets into small-pore macroencapsulation devices that prevent immune cell passage can inhibit allorejection in rodents. However, there are no reports of euglycemia in humans using this technology. This report further develops these macroencapsulation devices. We compared the ability of macroencapsulation transplant devic [...] |
A Novel Missense Variant in the CDH23 Gene is Segregated in an Iranian Family with Hearing Lossby
Abstract Sensorineural hearing loss (SNHL) describes a diverse group of clinically and genetically distinct disorders of the auditory system. SNHL is associated with mutations in up to 150 genes. Among them is Cadherin 23 (CDH23), which is associated with both Usher syndrome and non-syndromic hearing loss. In the current study, we used WES to find the genetic [...] |
A Case of Prenatal Diagnosis of Apert Syndrome in the Second Trimester of Pregnancyby
Abstract Craniosynostosis is a disorder characterized by premature closure of cranial sutures, resulting in restricted skull growth perpendicular to the affected suture and compensatory growth in other directions. Over 180 syndromes have been classified under craniosynostosis, of which eight are associated with mutations in the fibroblast growth factor receptor [...] |
The Prevalence of Autism in the World: An Umbrella Review and Meta-Analysisby
Abstract Autism is a neurodevelopmental disorder characterized by persistent challenges in social interactions and repetitive behaviors. This study aimed to investigate the prevalence of autism and autism spectrum disorder(ASD) in normal and abnormal groups, such as premature infants or seizure patients, using an umbrella review and meta-analysis. This stud [...] |
The Multi-Biophysical Nature of Computation in Brain Neural NetworksAbstract Comprehending the nature of nerve communication is fundamental to our understanding of the functioning of nervous systems in general. The ionic mechanisms underlying action potentials in the squid giant axon were first described by Hodgkin and Huxley in 1952, and their findings have formed our orthodox view of how the physiological action potential [...] |
Sustainable and Environmentally Friendly Approaches for Eliminating Alizarin Red S from Contaminated Water Using Hydroxyfluorapatite-Based BiomaterialsAbstract This study investigated the use of new bioadsorbent the Hydroxyfluorapatite (Ca10(PO4)6OH1.75F0.25, HFA) to eliminate Alizarin Red S (ARS), a harmful water pollutant. Initial batch tests were conducted to evaluate the adsorption process, focusing on both kinetics and equilibrium behavior. Various kinetic models were applied such as: pseudo first-order [...] |
Linking Brain, Hormones, and Metabolism: Pathophysiology and Treatment of Antipsychotic-Induced Cardiometabolic Side Effectsby
Abstract This narrative review explores the pathophysiological consequences, neuroendocrine processes, and treatment approaches aimed at reducing the cardiometabolic adverse effects linked to antipsychotic medications; in particular, it highlights recent mechanistic advances in receptor-mediated metabolic dysregulation and emerging therapeutic implications. [...] |
Complete Chloroplast Genome of Rauvolfia tetraphylla (Gentianales: Apocynaceae) and Phylogenetic AnalysisAbstract Rauvolfia tetraphylla L. (1753) is an important medicinal species of Apocynaceae, widely used for its rich indole alkaloids and related bioactive compounds. We report the first complete chloroplast genome of R. tetraphylla. The genome exhibits a typical circular quadripartite structure of 155,667 bp, with an overall GC content of 37.8%. The genome compr [...] |
Advances Toward In Vivo Cartilage Repair: A Comprehensive Review of Current Strategies and Future DirectionsAbstract The cartilage is avascular and has limited regenerative capacity, posing a significant clinical challenge. Conventional treatments often do not restore hyaline cartilage, leading to progressive osteoarthritis. Recent advances in tissue engineering have focused on integrating biomaterials, stem cells, growth factors, and gene-delivery approaches. In [...] |
A Qualitative Exploration: Black Women Living with DepressionAbstract Studies show Black women exhibit distinct depression symptoms and treatment experiences compared to other groups, often facing underdiagnosis and inadequate care. Unfortunately, knowledge about Black women with depression has been underexplored. Therefore, the purpose of this study is to gain a better understanding of Black women’s experiences living [...] |
Photovoltaic Power Forecasting Without Local Data: A Spatially-Aware Approach Using Neighboring Plantsby
Abstract The increasing demand for renewable energy sources has intensified the adoption of photovoltaic systems. This study proposes predictive models for solar power generation that operate without dependence on on-site meteorological stations. The proposed approach integrates generation data from geographically distributed plants and accounts for the distance [...] |
Phytochemically Rich Food-System By-Products in Ruminant Diets: Nutritional and Health Benefits from Animals to Humans within a Circular BioeconomyAbstract Food-system by-products (FSBP), including agricultural by-products, agro-industrial co-products, and food-processing residues, represent an underused source of nutrients and plant secondary compounds with significant potential in ruminant feeding systems. This review synthesized 96 peer-reviewed studies published between 2000 and 2025 on phytochemicall [...] |
Comprehensive Cytogenetic and ISSR Analysis in the Context of Conservation of the Local Breed of Brown Carpathian Cattle BreedAbstract The article reveals the variability of the genome of cattle of the local small-numbered domestic Brown Carpathian breed using cytogenetic and molecular genetic polylocus markers, and justifies the need to integrate local breeds into the modern system of agricultural production in accordance with FAO requirements. The work aimed to study the genetic [...] |
Beyond the Feed: Academic, Emotional, and Social Consequences of Social Media Use Among College StudentsAbstract In 2025, college students are reportedly more anxious and strained than any previous generation of young people, while they are also the first to have grown up entirely immersed in social media. This research explores social media use patterns and their relationship with academic, emotional, health-related and social well-being among college students [...] |
Central Post-Stroke Pain: Frequency, Clinical Characteristics, and Associated FactorsAbstract Central post-stroke pain (CPSP) is a frequently underrecognized complication that contributes to long-term disability among stroke survivors. This study aimed to determine the frequency of CPSP and to describe its clinical characteristics and associated factors among stroke patients treated at Arifin Achmad General Hospital. A cross-sectional design [...] |
Disability, Functional Limitations, and Family Violence among Older Adults in Brazil: A Cross-Sectional Study Using National Health Survey Data, Brazil 2019by
Abstract Elder abuse is a global public health issue, with consequences on individual health, increased burden on healthcare systems, and high social costs. The study aimed to estimate the prevalence of family violence among older adults in Brazil and analyze its association with disability, comorbidities, functional limitation, and sociodemographic characterist [...] |
Integrated Evaluation of Electric Submersible Pump Failures under Diverse Field Operating ConditionsAbstract Electrical submersible pumps (ESPs) are an efficient and reliable artificial lift method for lifting large volumes of fluids from wellbores at flexible rates. Despite their advantages, including high flow rates and real-time downhole telemetry, ESPs are prone to frequent and unforeseen failures under harsh reservoir conditions, resulting in costly produ [...] |
Challenges and Ethical Issues Related to Non-Invasive Prenatal Testing (NIPT)by
Abstract Non-invasive prenatal testing (NIPT) is now standard in prenatal care in many countries, even though it was introduced only about 15 years ago. Due to its rapid adoption into decades-old prenatal care plans, gynecologists, obstetricians, and the general public still struggle to understand the possibilities, benefits, and limitations of NIPT. The biggest [...] |
Assessment of Genetic Diversity and Polymorphism in Corylus avellana L. Pollen by Inter-Primer Binding Site Marker AnalysisAbstract Genetically conditioned variation in pollen has been demonstrated to have a substantial influence on reproductive mechanisms and population dynamics. The present study evaluated the genetic variability of 28 pollen samples of Corylus avellana L. using iPBS (Inter Primer Binding Sites Polymorphism) markers 1882 and 2152. The collection of biological [...] |
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