Open Access Research Article

B5N10 Nanocarrier Functionalized with Al, C, Si Atoms: A Drug Delivery Method for Infectious Disease Remedy

Received: 27 November 2023;  Published: 21 February 2024;  doi: 10.21926/obm.genet.2401214


As proof has recommended a close connection between COVID-19 and neurodegenerative disorders, this article aims to investigate the chloroquine (CLQ) drug as the SARS-CoV-2’s primary protease, which can prevent in vitro viral duplication of all diverse experiments to present. CLQ is an anti-viral drug enlarged by Pfizer, which can operate as an orall [...]

Open Access Commentary

Older LGBTQ People and Religious Abuse: Implications for the UK Regulation of Care Provision in Later Life

Received: 16 October 2023;  Published: 21 February 2024;  doi: 10.21926/obm.geriatr.2401270


Research suggests health, social care, and social work professionals who are highly religious, and adhere closely to traditional doctrine, are more likely to take a negative view of LGBTQ people. This includes those who provide services to older people. Negative attitudes towards lesbian, gay, bisexual, trans and/or queer (LGBTQ) people can translate [...]

Open Access Review

A Review of North American Prospects for Power and Hot-Water Generation with Thermal Energy

Received: 20 November 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401007


This article outlines an innovative approach to explore thermal energy extraction for power generation or industrial hot water applications. Unlike traditional steady-state models, this approach embraces time-variant scenarios, explicitly incorporating a cyclical fluid circulation strategy to maintain a stable surface fluid temperature or power output [...]

Open Access Original Research

Nonlinear Optimal Control for a PMLSG-VSC Wave Energy Conversion Unit

Received: 16 September 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401006


This article aims to treat the nonlinear control problem for the complex dynamics of a wave energy unit (WEC) that consists of a Permanent Magnet Linear Synchronous Generator (PMLSG) and a Voltage Source Converter (VSC). The article has developed a globally stable nonlinear optimal control method for this wave power generation unit. The new method avoid [...]

Open Access Review

Self-Healing Concrete Techniques and Technologies and Applications

Received: 30 April 2023;  Published: 21 February 2024;  doi: 10.21926/rpm.2401006


The main weakest point of concrete is its exposure to cracks, and concrete structure repair is expensive, especially for infrastructure maintenance, which is difficult to access. The ability of self-healing concrete (SHC) to successfully heal fractures without the assistance of humans has received much attention since it increases operational life and [...]

Open Access Original Research

Artocarpus Communis Seed Regulates P53, IRS, HsD17β2, FTO, and CYP11a Genes in Polycystic Ovarian Syndrome Rats

Received: 20 November 2023;  Published: 20 February 2024;  doi: 10.21926/obm.genet.2401213


Polycystic ovarian syndrome (PCOS) is a prevalent endocrine illness that affects 5-10% of reproductive women globally. It is a multifaceted hormonal disorder characterized by the involvement of numerous molecular mechanisms that contribute to its development. This study investigates the effect of Artocarpus communis seed on the hormonal imbalance and [...]

Open Access Review

Chronic Lung Allograft Dysfunction, a Review in 2023

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207


Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors [...]

Open Access Short Communication

Good or Great: Which One Are You?

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269


Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals [...]

Open Access Original Research

Erectile Function in Men during the COVID-19 Pandemic

Received: 25 August 2023;  Published: 18 February 2024;  doi: 10.21926/obm.icm.2401014


This research focused on two age groups of men (under 40 and over 40 years) and their sexual function during the COVID-19 pandemic. Somatic examinations, including the measurement of hormone levels, were conducted on all patients. The subjects also completed two questionnaires and provided personal history data. The first questionnaire covered the evalu [...]

Open Access Case Report

Examining the Carbon Management Strategies of Diebold Nixdorf

Received: 28 July 2023;  Published: 17 February 2024;  doi: 10.21926/aeer.2401007


Carbon management is imperative to curb global temperature increases and mitigating climate change impacts. This report explores the carbon management strategies employed by Diebold Nixdorf, a multinational financial and retail technology company. As of 2021, the company has not established specific reduction targets and has not committed to achieving [...]

Open Access Review

The Role of Cognition in Balance Control

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211


Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance [...]

Open Access Short Communication

Mental Health among the Elderly in Nepal: Special Emphasis on Depression

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268


This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particu [...]

Open Access Review

Floating Oscillating Water Column Wave Energy Converters: A Review of Developments

Received: 09 December 2023;  Published: 07 February 2024;  doi: 10.21926/jept.2401005


The main challenge in designing offshore renewable energy structures is to ensure their structural integrity on a life cycle basis while operating in harsh environments and, in parallel, being financially competitive and environmentally friendly concerning other types of energy systems. The Oscillating Water Column (OWC) converters are among the first [...]

Open Access Original Research

Do Magnetic Monopoles Exist?

Received: 21 October 2023;  Published: 07 February 2024;  doi: 10.21926/rpm.2401005


In this paper, we continue our previous work by discussing the consequences of curvature in spacetime caused by the presence of mass and the implications of this. We address the question raised by Dirac regarding the impact of a magnetic monopole on the quantum world. We discuss quantization concerning the solid angles observed, which may have a connect [...]

Open Access Original Research

Elementary Collective Effects in Systems Containing Small Fermion-Numbers

Received: 14 October 2023;  Published: 06 February 2024;  doi: 10.21926/rpm.2401004


One deals with an fermions collective where we encounter elementary emerging-collective phenomena at very low temperatures. This simplicity allows for expanding our insight on collective fermion behavior. We focus on several quantifiers, including standard ones related to thermal behavior, such as the von Neumann entropy, and quantifiers of other [...]

Open Access Research Article

Monitoring Energy-Loss-Driven-Cost by Using Earned Value Simulation in Complex Systems

Received: 24 July 2023;  Published: 06 February 2024;  doi: 10.21926/jept.2401004


The economic impact of energy loss stemming from end-user electricity consumption is a significant concern, with historical trends revealing escalating costs. Effectively managing both peak and off-peak demands remains a formidable challenge due to the unpredictable nature of consumer behaviors, leading to energy wastage. This study delves into the [...]

Open Access Original Research

Evaluation of Total Parenteral Nutrition in the Autologous Transplantation Setting in Patients with AML: A Retrospective Exploratory Analysis

Received: 29 July 2023;  Published: 04 February 2024;  doi: 10.21926/obm.transplant.2401206


Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parenteral nutrition in this setting. This observational, non [...]

Open Access Original Research

Efficacy and Safety of Andrographolide and Favipiravir Versus Favipiravir Monotherapy in Patients with Mild COVID-19 Infection: A Multicenter Randomized Controlled Trial

Received: 08 December 2023;  Published: 02 February 2024;  doi: 10.21926/obm.icm.2401013


Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022. The patients were rando [...]

Open Access Editorial

Pain and Neurobiology

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210


Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adapta [...]

Open Access Review

Exploring the Regenerative Potential of Stem Cells for Treating Eye Diseases: A Review of the New Findings

Received: 27 September 2023;  Published: 31 January 2024;  doi: 10.21926/obm.genet.2401212


The escalating prevalence of vision loss due to eye diseases has instigated a quest for innovative therapies, given that conventional approaches often fall short in repairing and regenerating damaged eye tissues, particularly the retina. Stem cell-based interventions have emerged as a promising avenue, with numerous studies in animal models and human [...]

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