OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period). 

Open Access Original Research

Improving Confidence in Dementia Care by Helping Care Staff Articulate Skills They Already Possess: The Value of the Communication and Interaction Training (CAIT) Programme

Received: 14 August 2022;  Published: 18 January 2023;  doi: 10.21926/obm.geriatr.2301222

Abstract

This article discusses the findings from a training programme called ‘Communication and Interaction Training’ (CAIT). CAIT was designed to improve the confidence of carers in their use of communication skills with people living with dementia, particularly when managing behavioural agitation. This pre/post assessment study employed a mixed design [...]

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/obm.geriatr.2301221

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...]

Open Access Original Research

Brain Imaging Studies Using Deep Neural Networks in the Detection of Alzheimer's Disease

Received: 29 June 2022;  Published: 03 January 2023;  doi: 10.21926/obm.geriatr.2301220

Abstract

The increasing incidence of adult-onset dementia disorders and primarily Alzheimer’s disease (AD) among the aging population around the world is increasing the social and economic burden on society and healthcare systems. This paper presents three neural networking algorithms: MobileNet, Artificial Neural Networks (ANN), and DenseNet for AD classifica [...]

Open Access Original Research

Association of Stress with Healthy Aging, the Role of Physical Activity

Received: 14 October 2022;  Published: 29 December 2022;  doi: 10.21926/obm.geriatr.2204219

Abstract

The World Health Organization attracted more attention to the positive effects of physical activity (PA) and the adverse effects of stress on the health of older people and, therefore, attracted a more significant number of practitioners. To verify the impact of PA on stress in older people. Observational and analytical research, composed of 690 older [...]

Open Access Original Research

4Active Intervention for Promoting Physical Activity and Cognitive Flexibility Among Older Adults

Received: 03 July 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204218

Abstract

Physical activity is essential to delaying cognitive decline and preventing cognitive impairment in older adults. We designed and implemented two-level 4Active intervention for older adults living in retirement communities. This study aimed to examine the effectiveness of the 4Active intervention in increasing physical activity and cognitive function [...]

Open Access Original Research

The Effects of Control Measures and Social Networks on Depression Among Older People During the SARS-CoV-2 Pandemic

Received: 26 June 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204217

Abstract

This study examined the correlates of change in the depressed state among people aged 65 and older during the SARS-CoV-2 pandemic, particularly the effects of crucial pandemic-related variables. Data were drawn from the longitudinal Survey of Health, Ageing and Retirement in Europe (SHARE), including information obtained from two special pandemic-relate [...]

Open Access Original Research

Health-Related Quality of Life (HRQoL) in Elderly Patients Attending at Tertiary Health Care Centre in Central India During 1st Wave of COVID-19 Pandemic: A Prospective Observational Study

Received: 22 August 2022;  Published: 11 December 2022;  doi: 10.21926/obm.geriatr.2204216

Abstract

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is a lack of studies on the health-related quality of life (HRQoL) in the elderly in countries like India during COVID-19. After obtaining written informed consent from the elderly patients, data was [...]

Open Access Research Article

The Effect of Irradiation on the Skin upon Breast Cancer Radiotherapy Studied by FTIR Spectroscopy

Received: 12 September 2022;  Published: 24 November 2022;  doi: 10.21926/obm.geriatr.2204215

Abstract

Breast cancer affects the female population worldwide. Radiotherapy (RT) is part of the therapeutic modality in the management of breast cancer, after radical mastectomy or conserving surgery. The FTIR spectroscopic “marker bands” will lead us to approach the mechanism of skin damage due to the interaction of ionizing radiation and skin, on a molecu [...]

Open Access Review

Cardiovascular Comorbidities and Cognitive Impairment

Received: 23 August 2022;  Published: 23 November 2022;  doi: 10.21926/obm.geriatr.2204214

Abstract

Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and [...]

Open Access Research Article

Finding Positives Amidst the Negatives: A Thematic Analysis of the Impact of the COVID-19 Pandemic on Canadians 55+

Received: 31 July 2022;  Published: 17 November 2022;  doi: 10.21926/obm.geriatr.2204213

Abstract

Disasters such as the COVID-19 pandemic exact a toll on vulnerable populations in terms of morbidity and mortality, but they also provide opportunities for personal growth and development and demonstration of personal and collective resiliency. This inductive thematic analysis explores self-perceived negative and positive impacts of the COVID-19 pandemi [...]

Open Access Original Research

Dental Services Utilization by over 65 Years Old in Israel in 2020

Received: 01 May 2022;  Published: 17 November 2022;  doi: 10.21926/obm.geriatr.2204212

Abstract

To understand dental service utilization in the over-65 age group and to identify the main patterns and barriers to uptake of dental care after the 2019 expansion under the National Health Insurance Law to include dental benefits for the over-75 age group. Phone interviews with a random sample of 512 people over the age of 65 were conducted between [...]

Open Access Original Research

Happy and Satisfied in Very Late Life? Findings from the Health and Retirement Study

Received: 01 July 2022;  Published: 14 November 2022;  doi: 10.21926/obm.geriatr.2204211

Abstract

This research aims to examine cross-sectional and longitudinal associations of positive subjective well-being among centenarians and near-centenarians in the Health and Retirement Study. Participants who eventually survived to age 98 or older (N = 516) were included. Study variables included demographic characteristics, health and activities of dail [...]

Open Access Original Research

Exploring Spousal Relationships Post-Stroke and the Association Between Relationship Congruence and Dysphagia-Related Caregiver Burden

Received: 11 August 2022;  Published: 07 November 2022;  doi: 10.21926/obm.geriatr.2204210

Abstract

Stroke survivors often receive spousal support for post-stroke impairments. The quality of spousal caregiving and couples’ wellbeing can suffer from post-stroke relationship changes and caregiver burden. Because swallowing impairment (dysphagia) is common post-stroke and spouses providing dysphagia care may experience burden, it is also important [...]

Open Access Original Research

An Exploratory Study of How Mobile Devices are Used by Older Adults

Received: 08 August 2022;  Published: 17 October 2022;  doi: 10.21926/obm.geriatr.2204209

Abstract

Despite the increase in use and interest in mobile devices by older adults, to date, there is still limited research carried out to better understand older adults’ usage and needs as they relate to such devices. As such, this research examined the use of two types of mobile devices, smartphones, and tablets, by older adults (i.e., age 65+), as well [...]

Open Access Review

Perspectives to Modify and Counter Aging in the Frame of Subtelomere–Telomere Theory of Aging

Received: 22 July 2022;  Published: 14 October 2022;  doi: 10.21926/obm.geriatr.2204208

Abstract

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The [...]

Open Access Interview

An Interview with Dr. David G. Smithard

Received: 09 October 2022;  Published: 09 October 2022;  doi: 10.21926/obm.geriatr.2204207

Abstract

Open AccessOBM GeriatricsInterviewAn Interview with Dr. David G. SmithardOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 4 doi:10.21926/obm.geriatr.2204207Received: October 09, 2022Accepted: October 09, 2022Pu [...]

Open Access Review

Myokine Response to Resistance Exercise in Older Adults and the Similarities and Differences to Younger Adults: A Brief Narrative Review

Received: 30 May 2022;  Published: 07 October 2022;  doi: 10.21926/obm.geriatr.2204206

Abstract

Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of mainta [...]

Open Access Short Report

Creation of an Operational Dashboard to Document Implementation of 4M’s into Primary Care in a Geriatric Patient-Centered Medical Home

Received: 05 June 2022;  Published: 28 September 2022;  doi: 10.21926/obm.geriatr.2203205

Abstract

Many health systems have joined the Age-Friendly Health Systems movement to provide every older adult safe, high-quality care aligned with what matters most. Becoming an Age-Friendly Health System means that hospitals and health care systems reliably use a set of evidence-based practices known as the “4M’s” – What Matters, Medication, Mentation [...]

Open Access Case Report

Sleep Disorders in Older People with Special Focus on Parkinson’s Disease

Received: 01 July 2022;  Published: 13 September 2022;  doi: 10.21926/obm.geriatr.2203204

Abstract

This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which may be a precursor to [...]

Open Access Original Research

A Retrospective Study of Progressive Gait Impairment in Alzheimer’s Disease

Received: 27 December 2021;  Published: 08 September 2022;  doi: 10.21926/obm.geriatr.2203203

Abstract

Individuals with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI) have increased gait disturbances throughout disease progression. However, an understanding of gait impairment and progression in early versus late AD is lacking. Further, the longitudinal progression of gait impairment in AD as well as in those with MCI that transition to [...]

Open Access Review

Polymyalgia Rheumatica, an Age-Related Rheumatic Disease

Received: 07 May 2022;  Published: 27 July 2022;  doi: 10.21926/obm.geriatr.2203202

Abstract

Polymyalgia rheumatica (PMR) is an age-related chronic inflammatory disease with rheumatic features at the fore. In addition to the high-grade systemic inflammation, it is characterized by typical “polymyalgic” musculoskeletal symptoms, including diffuse and severe pain and prolonged morning stiffness of the shoulder girdle, pelvic girdle, and neck [...]

Open Access Interview

An Interview with Dr. Koh Iwasaki

Received: 01 July 2022;  Published: 03 July 2022;  doi: 10.21926/obm.geriatr.2203201

Open Access Review

Complex Pathology of Cardiac Syncope in Old Patients

Received: 07 February 2022;  Published: 16 June 2022;  doi: 10.21926/obm.geriatr.2202200

Abstract

Syncope is characterized by a transient and rapid loss of consciousness for a short duration, with full spontaneous recovery within minutes. Syncope causes up to 2% of all emergency medical consultations. The incidence of syncope is similar in men and women, is higher in old patients (slightly higher in old women). The prevalence of syncope is up to [...]

Open Access Interview

An Interview with Dr. Carlo Pedrolli

Received: 01 June 2022;  Published: 09 June 2022;  doi: 10.21926/obm.geriatr.2202199

Abstract

InterviewAn Interview with Dr. Carlo PedrolliOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 2 doi:10.21926/obm.geriatr.2202199Received: June 01, 2022Accepted: June 02, 2022Published: June 09, 2022

Open Access Review

Omega-3 Long-Chain Polyunsaturated Fatty Acids in the Elderly: A Review

Received: 28 February 2022;  Published: 19 May 2022;  doi: 10.21926/obm.geriatr.2202198

Abstract

The omega-3 long-chain polyunsaturated fatty acids (omega-3 LC-PUFAs) family includes eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA). Although seafood is the richest source of omega-3 LC-PUFAs, because diet alone is often insufficient in older people, they may require food supplements and enriched food as source [...]

2nd Mediterranean Congress of Anti-aging Medicine 2022

14–16 October 2022, Larnaca, Cyprus

This is the second time a conference with such a wide-ranging theme on aging is held in Cyprus. The 1st Mediterranean Congress of Antiaging Medicine was held in Larnaca on 13-14 April 2019. The health of older people is a crucial subject which involves a multidisciplinary approach in order to offer effective treatments against age-related diseases. The conference is comprehensive and practical, involving both basic science and clinical therapies. Lectures, presentations and seminars will be delivered by world-class academics, and by clinicians of European prestige. It will be attended by scientists working in the science of aging both from Cyprus and from Europe, Israel, Russia, United Kingdom, as well as clinicians, health professionals and others with interest in applied, effective interventions which may help reduce the impact of aging upon society. We expect wide media coverage as well as publicity reaching European, Asian and American countries.

For more information, visit the official website at: https://mcamcyprus.org/

26th World Congress on Medical Law

December 5th- 7th, 2022, Gold Coast, Australia

The purpose of the WAML is to encourage the study and discussion of health law, legal medicine and ethics, for the benefit of society and the advancement of human rights. The aim of the WAML is to promote the study of the consequences in jurisprudence, legislation and ethics of developments in medicine, health care and related sciences.

Congress Themes:

   1. Impact of Covid on Legal Medicine

   2. Medicine and technology

   3. Concussion and Traumatic brain injury

For more details, please visit: http://wafml.memberlodge.org/, http://lidsen.com/2022 WCML Brochure FINAL.

World CB & CDx 2022

April 27-28, 2022, London, UK

As the precision medicine industry witnesses exciting Drug-Dx approvals being driven by major advancements in biomarker development, the 12th Clinical Biomarker & CDx Summit Europe returns in 2022 to set the stage for key learnings with exclusive data to optimise your drug development programmes with the most cutting-edge tools and techniques from start to finish.

Against the backdrop of complex IVDR changes creating industry-wide uncertainty, CB & CDx Europe returns at an all-important moment in time as Europe’s only end-to-end clinical biomarker and CDx summit. Uniting the entire value chain of precision medicine leaders, here you can find the latest updates, intelligence and clarity to overcome your portfolio planning hurdles.

Delving deep into the most ground-breaking work enabling patient population identification, and pairing this with revelations from streamlined commercial strategies, this is an industry poised to gain actionable insights maximising access to game-changing precision medicines and testing technology in European markets.

Join with 300+ major stakeholders of the European drug-diagnostics field to forge successful scientific and commercialization co-development strategies at a pivotal moment for precision medicine.

For more details, please visit: https://cdx-europe.com/

Alzheimer's Association International Conference

July 31 – August 4, 2022, San Diego, USA and Online

Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.
For more details, please visit: https://www.alz.org/aaic/overview.asp

International Continence Society

September 07-10, 2022, Vienna, Australia

What to Expect at ICS 2022

ICS 2022 in Vienna will be a great 4-day meeting, offering a range of sessions and topics depending upon your speciality and interests.

The ICS annual meeting brings together the most renowned international experts in the research and the treatment of LUTS, incontinence and pelvic foor disorders. The meeting is multidisciplinary and welcomes urologists, gynaecologists, neurourologists, physiotherapists, nurses, midwives and research scientists.

ICS 2022 State of the Art Lectures and Round Table Debates

Expect to hear from world class leaders in the field of incontinence. Their lectures and discussions will bring you the cutting-edge information about pelvic floor dysfunction. We are pleased to confirm our 2022 State of the Art Lectures.

For more details, please visit:https://www.ics.org/2022

13th Clinical Trials on Alzheimer's Disease (CTAD)

November 4-7, 2020, Boston, USA

The development of the next generation of Alzheimer’s disease treatments is among the most important health needs worldwide, but presents huge challenges. The goal of the meeting is to bring together today’s worldwide leaders in the treatment of Alzheimer’s disease to discuss new results, candidate therapeutics, and methodological issues important to the development of the next generation of Alzheimer’s disease treatments.

Clinical trial teams from worldwide centers will report on their efforts to identify new biomarkers of disease as well as more sensitive clinical assessment tools to identify those at risk for AD, to predict progression, and assess the effectiveness of new treatments.

For more details, please visit: https://www.ctad-alzheimer.com/ctad-2020

Alzheimer's Association International Conference®

July 26-30, 2020, Amsterdam, Netherlands

AAIC 2020 will bring together international investigators, clinicians and care researchers to discuss the latest studies, theories and discoveries that will help bring the world closer to breakthroughs in dementia science.

For more details, please visit: https://www.alz.org/aaic/overview.asp

Integrative Regen Group

February 29- March 2, 2020, Arizona Biltmore Resort, USA

Who: Providers of all disciplines who are passionate about or interested in regenerative medicine are encouraged to attend this event. The agenda will be packed full of actionable topics that most attendees will be able to put into effect immediately to continue to provide their patients with the most cutting-edge therapies.

What: Integrative Regen Group’s second conference will be bringing together experts in all areas of regenerative medicine, from stem cells to photobiomodulation, peptides to hormones, and everything in between. It is our goal that every person in attendance increase their knowledge base substantially.

For more details, please visit: https://www.intregengroup.com/

The 2nd Longevity Therapeutics

January 28-30, 2020, San Francisco CA, USA

With rapid advances in the understanding of the underlying biology and mechanisms of aging, ground-breaking research and technology are coming together to target aging pathways, in a way to prevent, reverse or delay the onset of age-related conditions, and consequently improve heathspan.

The 2nd Longevity Therapeutics 2020 Summit will once again bring together 80+ leading experts in aging-related research, including biotechs, pharma, academics and investors, who are committed to serving worldwide population with innovative drugs to prevent, delay and treat age-related conditions.

For more details, please visit: https://longevity-therapeutics.com/

OBM Geriatrics welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.

Announcement
Newsletter
Highlight

Highlight

by Michael Fossel

OBM Geriatrics 2023

Published: 15 January 2020

Highlight from: A unified model of dementias and age‐related neurodegeneration.

Michael Fossel.

Alzheimer’s & Dementia.

doi: 10.1002/alz.12012.

Highly Accessed Articles

Case Report

by Garuth Chalfont et al.

OBM Geriatrics 2023

Published: 07 August 2019

Perspective

by Robert Conder et al.

OBM Geriatrics 2023

Published: 20 March 2019

Review

by Michael Fossel

OBM Geriatrics 2023

Published: 15 February 2019

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