OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.7 weeks; Submission to Acceptance: 17.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

Open Access Research Article

What Do We Know about an Invisible Issue? Results of a Scoping Review of Elder Abuse and Gender and Sexual Minorities

Received: 04 January 2024;  Published: 18 March 2024;  doi: 10.21926/obm.geriatr.2401274

Abstract

Elder abuse occurs to older adults who are members of gender and sexual minorities (GSM). Whilst most of that abuse is similar to that experienced by their heterosexual and cisgender peers GSM older adults face particular vulnerabilities due to their life experiences and changes. In this article we report on our findings from a literature search and [...]

Open Access Review

Impact of Sex and Gender Differences on Heart Failure, Especially in Elderly Patients

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Abstract

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older [...]

Open Access Research Article

Resilience and Adaptability of Older Adults: Findings from the COVID-19 Impact Survey

Received: 08 January 2024;  Published: 06 March 2024;  doi: 10.21926/obm.geriatr.2401272

Abstract

The COVID-19 pandemic caused abrupt changes in daily routines, social connections, and ways of life. It is yet unknown the full impacts these extended changes have had on the long-term mental well-being of those who shared this global experience. As a contribution to our overall understanding of this phenomena, this study explored the effects of the [...]

Open Access Review

Trajectories and Status of Transgender Elderly Across the World and in Spain: A Narrative Review

Received: 06 November 2023;  Published: 27 February 2024;  doi: 10.21926/obm.geriatr.2401271

Abstract

Older trans people have been largely unaddressed both in the context of the LGBTIQ+ community and in studies on geriatrics and aging. This literature review compiles up-to-date information on transgender elders, providing a summary of the Spanish historical context in which trans people have been raised, and analyzes the areas in which to center possibl [...]

Open Access Commentary

Older LGBTQ People and Religious Abuse: Implications for the UK Regulation of Care Provision in Later Life

Received: 16 October 2023;  Published: 21 February 2024;  doi: 10.21926/obm.geriatr.2401270

Abstract

Research suggests health, social care, and social work professionals who are highly religious, and adhere closely to traditional doctrine, are more likely to take a negative view of LGBTQ people. This includes those who provide services to older people. Negative attitudes towards lesbian, gay, bisexual, trans and/or queer (LGBTQ) people can translate [...]

Open Access Short Communication

Good or Great: Which One Are You?

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269

Abstract

Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals [...]

Open Access Short Communication

Mental Health among the Elderly in Nepal: Special Emphasis on Depression

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268

Abstract

This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particu [...]

Open Access Research Article

The Indigo Project: Participatory Action Research with Gender and Sexual Minority Survivors of Elder Abuse

Received: 27 November 2023;  Published: 31 January 2024;  doi: 10.21926/obm.geriatr.2401267

Abstract

Though research suggests that older adults belonging to gender and sexual minorities (GSM) are at greater risk of abuse and neglect, more needs to be done to investigate this situation, provide solid data, offer support to survivors and better inform those providing services. This article reports on a participatory action research project in which nine [...]

Open Access Concept Paper

Using Elder Abuse Case Studies to Develop LGBTQ+ Cultural Competency

Received: 16 July 2023;  Published: 15 January 2024;  doi: 10.21926/obm.geriatr.2401266

Abstract

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) elders are vulnerable to both the “usual” types of elder abuse (physical, sexual, emotional, and financial abuse, along with neglect), and with abuse that is specific to the context and history of LGBTQ+ elders. Training for adult protective services, long-term care ombudsmen, and other profess [...]

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2023

Received: 03 January 2024;  Published: 04 January 2024;  doi: 10.21926/obm.geriatr.2401265

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...]

Open Access Original Research

Active Aging for L.I.F.E.: An Intergenerational Program for Addressing and Changing Attitudes Toward Longevity

Received: 19 July 2022;  Published: 27 December 2023;  doi: 10.21926/obm.geriatr.2304264

Abstract

The global population of adults 65 years of age and older will increase dramatically over the next several decades, presenting economic and social challenges requiring sustainable solutions. Aging is a process in which everyone is already involved, it is a lifelong experience not just a later life occurrence. Changing world demographics illustrate that [...]

Open Access Original Research

Cell Level- Modeling of Aging and Rejuvenation

Received: 14 April 2023;  Published: 22 December 2023;  doi: 10.21926/obm.geriatr.2304263

Abstract

Understanding processes related to human aging and rejuvenation relies on experimental data and advanced models operating at different levels. There are several existing conceptual and specific modeling approaches. However, one of the existing tasks is compiling generic models linking properties at cell and cell-element levels to properties at systemic [...]

Open Access Review

AI-Powered Solutions to Support Informal Caregivers in Their Decision-Making: A Systematic Review of the Literature 1

Received: 15 October 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304262

Abstract

Due to aging demographics, prolonged life expectancy, and chronic diseases, European societies' increasing need for care services has led to a shift towards informal care supplied by family members, friends, or neighbors. However, the progressive decrease in the caregiver-to-patient ratio will result in a significant augmentation in incorporating intell [...]

Open Access Original Research

Examining the Role Between Social Antecedents and Depression among LGBTQ+ Older Adults Eligible for Low-Income Housing

Received: 28 July 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304261

Abstract

Housing is one of the top four most needed services for LGBTQ+ older adults, and this study focuses on the intersection of depression and social antecedents among LGBTQ+ older adults eligible for low-income housing. To explore social antecedents (i.e., demographics, early events, later events, social integration, and stressors) associated with screening [...]

Open Access Original Research

Sexual Orientation and Risk for Elder Abuse: Findings from the Canadian Longitudinal Study on Aging

Received: 03 October 2023;  Published: 04 December 2023;  doi: 10.21926/obm.geriatr.2304260

Abstract

This study addresses knowledge gaps concerning prevalence and risk factors for elder abuse among sexual minority (SM) compared to heterosexual Canadians aged 65+. Data derive from the Canadian Longitudinal Study on Aging, a national cohort study. Outcome variables include self-reports of psychological, physical, or financial abuse in the 12 months befor [...]

Open Access Original Research

Adaptation to Residential Care: Voices from New Zealand

Received: 25 May 2023;  Published: 01 December 2023;  doi: 10.21926/obm.geriatr.2304259

Abstract

This article explores the adaptation process of older adults in residential care facilities in New Zealand. Through a phenomenological approach, this study provides clarity on how older adults adjust in residential care despite losses and challenges. Qualitative data on 24 older adults, 6 residential care facilities, and 10 staff were collected. Utilisi [...]

Open Access Original Research

Where Older Patients with Cancer Die? A Retrospective Study

Received: 10 July 2023;  Published: 16 November 2023;  doi: 10.21926/obm.geriatr.2304258

Abstract

Home is the preferred place of death for most cancer patients. We examined which characteristics of older patients with cancer may have influenced this choice and how important may be relevant an early collaboration between oncologists and palliatives. Hospitalized patients aged ≥70 were screened by G8 questionnaire and evaluated by Comprehensive [...]

Open Access Research Article

Phytomodification Effects of Visceral Lymph Node Aging

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Abstract

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential [...]

Open Access Short Communication

Narratives about Menopause

Received: 28 August 2023;  Published: 30 October 2023;  doi: 10.21926/obm.geriatr.2304256

Abstract

Narratives and how women interpret their symptoms have always been a part of how menopause is experienced. Today, as women feel more accessible to talk about menopause, new narratives are being formed and negotiated - both to menopause and concerning women becoming older. These different narratives mirror the fact that the transitional phase differs [...]

Open Access Short Review

The Pathophysiology and Management of NAFDL in Post-menopausal Women: An Updated Short Review

Received: 10 May 2023;  Published: 26 October 2023;  doi: 10.21926/obm.geriatr.2304255

Abstract

Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. [...]

Open Access Review

The Impact of Climate Change on Older Adults’ Mental Health: A Primer for Clinicians

Received: 31 July 2023;  Published: 24 October 2023;  doi: 10.21926/obm.geriatr.2304254

Abstract

Climate change is a major public health emergency. Natural disasters (earthquakes, floods, hurricanes, tornadoes, tsunamis, landslides, wildfires, and volcanic eruptions) have been increasing in frequency and severity and can cause lasting psychological sequelae. Older adults are highly vulnerable to the physical and mental health impacts of extreme [...]

Open Access Short Review

Age-Related Pathologies and Life Span

Received: 27 July 2023;  Published: 11 October 2023;  doi: 10.21926/obm.geriatr.2304253

Abstract

Both from a healthcare and a socioeconomic perspective, research on senescence is increasingly essential. Indeed, in industrialized countries, the increased human longevity confronts medicine with many old patients with age-related pathologies. The paper reviews the biological theories on aging, the impact of reactive oxygen species, telomers, epigeneti [...]

Open Access Review

Screening and Treating Urinary Incontinence in Primary Care: A Missed Opportunity

Received: 12 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304252

Abstract

More than 60% of adult women in the United States have urinary incontinence (UI), with the prevalence increasing to over 80% in women over age 65. Despite its high prevalence, most patients do not seek care and few clinicians screen for UI. The Medicare Health Outcomes Survey queries patients about satisfaction with their provider’s discussion and [...]

Open Access Review

Mixed Urinary Incontinence: Diagnosis and Management

Received: 17 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304251

Abstract

The evaluation and treatment of mixed urinary incontinence receives relatively little attention as compared to other forms of incontinence. Mixed incontinence, however, defined as the combination of stress and urgency incontinence, accounts for the largest proportion of incontinence, with an increased incidence in older women. The condition can be ver [...]

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250

Abstract

As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into [...]

2nd Mediterranean Congress of Anti-aging Medicine 2022

14–16 October 2022, Larnaca, Cyprus

This is the second time a conference with such a wide-ranging theme on aging is held in Cyprus. The 1st Mediterranean Congress of Antiaging Medicine was held in Larnaca on 13-14 April 2019. The health of older people is a crucial subject which involves a multidisciplinary approach in order to offer effective treatments against age-related diseases. The conference is comprehensive and practical, involving both basic science and clinical therapies. Lectures, presentations and seminars will be delivered by world-class academics, and by clinicians of European prestige. It will be attended by scientists working in the science of aging both from Cyprus and from Europe, Israel, Russia, United Kingdom, as well as clinicians, health professionals and others with interest in applied, effective interventions which may help reduce the impact of aging upon society. We expect wide media coverage as well as publicity reaching European, Asian and American countries.

For more information, visit the official website at: https://mcamcyprus.org/

26th World Congress on Medical Law

December 5th- 7th, 2022, Gold Coast, Australia

The purpose of the WAML is to encourage the study and discussion of health law, legal medicine and ethics, for the benefit of society and the advancement of human rights. The aim of the WAML is to promote the study of the consequences in jurisprudence, legislation and ethics of developments in medicine, health care and related sciences.

Congress Themes:

   1. Impact of Covid on Legal Medicine

   2. Medicine and technology

   3. Concussion and Traumatic brain injury

For more details, please visit: http://wafml.memberlodge.org/, http://lidsen.com/2022 WCML Brochure FINAL.

World CB & CDx 2022

April 27-28, 2022, London, UK

As the precision medicine industry witnesses exciting Drug-Dx approvals being driven by major advancements in biomarker development, the 12th Clinical Biomarker & CDx Summit Europe returns in 2022 to set the stage for key learnings with exclusive data to optimise your drug development programmes with the most cutting-edge tools and techniques from start to finish.

Against the backdrop of complex IVDR changes creating industry-wide uncertainty, CB & CDx Europe returns at an all-important moment in time as Europe’s only end-to-end clinical biomarker and CDx summit. Uniting the entire value chain of precision medicine leaders, here you can find the latest updates, intelligence and clarity to overcome your portfolio planning hurdles.

Delving deep into the most ground-breaking work enabling patient population identification, and pairing this with revelations from streamlined commercial strategies, this is an industry poised to gain actionable insights maximising access to game-changing precision medicines and testing technology in European markets.

Join with 300+ major stakeholders of the European drug-diagnostics field to forge successful scientific and commercialization co-development strategies at a pivotal moment for precision medicine.

For more details, please visit: https://cdx-europe.com/

Alzheimer's Association International Conference

July 31 – August 4, 2022, San Diego, USA and Online

Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.
For more details, please visit: https://www.alz.org/aaic/overview.asp

International Continence Society

September 07-10, 2022, Vienna, Australia

What to Expect at ICS 2022

ICS 2022 in Vienna will be a great 4-day meeting, offering a range of sessions and topics depending upon your speciality and interests.

The ICS annual meeting brings together the most renowned international experts in the research and the treatment of LUTS, incontinence and pelvic foor disorders. The meeting is multidisciplinary and welcomes urologists, gynaecologists, neurourologists, physiotherapists, nurses, midwives and research scientists.

ICS 2022 State of the Art Lectures and Round Table Debates

Expect to hear from world class leaders in the field of incontinence. Their lectures and discussions will bring you the cutting-edge information about pelvic floor dysfunction. We are pleased to confirm our 2022 State of the Art Lectures.

For more details, please visit:https://www.ics.org/2022

13th Clinical Trials on Alzheimer's Disease (CTAD)

November 4-7, 2020, Boston, USA

The development of the next generation of Alzheimer’s disease treatments is among the most important health needs worldwide, but presents huge challenges. The goal of the meeting is to bring together today’s worldwide leaders in the treatment of Alzheimer’s disease to discuss new results, candidate therapeutics, and methodological issues important to the development of the next generation of Alzheimer’s disease treatments.

Clinical trial teams from worldwide centers will report on their efforts to identify new biomarkers of disease as well as more sensitive clinical assessment tools to identify those at risk for AD, to predict progression, and assess the effectiveness of new treatments.

For more details, please visit: https://www.ctad-alzheimer.com/ctad-2020

Alzheimer's Association International Conference®

July 26-30, 2020, Amsterdam, Netherlands

AAIC 2020 will bring together international investigators, clinicians and care researchers to discuss the latest studies, theories and discoveries that will help bring the world closer to breakthroughs in dementia science.

For more details, please visit: https://www.alz.org/aaic/overview.asp

Integrative Regen Group

February 29- March 2, 2020, Arizona Biltmore Resort, USA

Who: Providers of all disciplines who are passionate about or interested in regenerative medicine are encouraged to attend this event. The agenda will be packed full of actionable topics that most attendees will be able to put into effect immediately to continue to provide their patients with the most cutting-edge therapies.

What: Integrative Regen Group’s second conference will be bringing together experts in all areas of regenerative medicine, from stem cells to photobiomodulation, peptides to hormones, and everything in between. It is our goal that every person in attendance increase their knowledge base substantially.

For more details, please visit: https://www.intregengroup.com/

The 2nd Longevity Therapeutics

January 28-30, 2020, San Francisco CA, USA

With rapid advances in the understanding of the underlying biology and mechanisms of aging, ground-breaking research and technology are coming together to target aging pathways, in a way to prevent, reverse or delay the onset of age-related conditions, and consequently improve heathspan.

The 2nd Longevity Therapeutics 2020 Summit will once again bring together 80+ leading experts in aging-related research, including biotechs, pharma, academics and investors, who are committed to serving worldwide population with innovative drugs to prevent, delay and treat age-related conditions.

For more details, please visit: https://longevity-therapeutics.com/

OBM Geriatrics welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.

Newsletter
Highlight

Highlight

by Michael Fossel

OBM Geriatrics 2024

Published: 15 January 2020

Highlight from: A unified model of dementias and age‐related neurodegeneration.

Michael Fossel.

Alzheimer’s & Dementia.

doi: 10.1002/alz.12012.

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