OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.


Archiving: full-text archived in CLOCKSS.

Publication Speed (median values for papers published in 2022): Submission to First Decision: 5 weeks; Submission to Acceptance: 14 weeks; Acceptance to Publication: 11 days (1-2 days of FREE language polishing included)

Open Access Original Research

Sexual Orientation and Risk for Elder Abuse: Findings from the Canadian Longitudinal Study on Aging

Received: 03 October 2023;  Published: 04 December 2023;  doi: 10.21926/obm.geriatr.2304260


This study addresses knowledge gaps concerning prevalence and risk factors for elder abuse among sexual minority (SM) compared to heterosexual Canadians aged 65+. Data derive from the Canadian Longitudinal Study on Aging, a national cohort study. Outcome variables include self-reports of psychological, physical, or financial abuse in the 12 months befor [...]

Open Access Original Research

Adaptation to Residential Care: Voices from New Zealand

Received: 25 May 2023;  Published: 01 December 2023;  doi: 10.21926/obm.geriatr.2304259


This article explores the adaptation process of older adults in residential care facilities in New Zealand. Through a phenomenological approach, this study provides clarity on how older adults adjust in residential care despite losses and challenges. Qualitative data on 24 older adults, 6 residential care facilities, and 10 staff were collected. Utilisi [...]

Open Access Original Research

Where Older Patients with Cancer Die? A Retrospective Study

Received: 10 July 2023;  Published: 16 November 2023;  doi: 10.21926/obm.geriatr.2304258


Home is the preferred place of death for most cancer patients. We examined which characteristics of older patients with cancer may have influenced this choice and how important may be relevant an early collaboration between oncologists and palliatives. Hospitalized patients aged ≥70 were screened by G8 questionnaire and evaluated by Comprehensive [...]

Open Access Research Article

Phytomodification Effects of Visceral Lymph Node Aging

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257


Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential [...]

Open Access Short Communication

Narratives about Menopause

Received: 28 August 2023;  Published: 30 October 2023;  doi: 10.21926/obm.geriatr.2304256


Narratives and how women interpret their symptoms have always been a part of how menopause is experienced. Today, as women feel more accessible to talk about menopause, new narratives are being formed and negotiated - both to menopause and concerning women becoming older. These different narratives mirror the fact that the transitional phase differs [...]

Open Access Short Review

The Pathophysiology and Management of NAFDL in Post-menopausal Women: An Updated Short Review

Received: 10 May 2023;  Published: 26 October 2023;  doi: 10.21926/obm.geriatr.2304255


Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. [...]

Open Access Review

The Impact of Climate Change on Older Adults’ Mental Health: A Primer for Clinicians

Received: 31 July 2023;  Published: 24 October 2023;  doi: 10.21926/obm.geriatr.2304254


Climate change is a major public health emergency. Natural disasters (earthquakes, floods, hurricanes, tornadoes, tsunamis, landslides, wildfires, and volcanic eruptions) have been increasing in frequency and severity and can cause lasting psychological sequelae. Older adults are highly vulnerable to the physical and mental health impacts of extreme [...]

Open Access Short Review

Age-Related Pathologies and Life Span

Received: 27 July 2023;  Published: 11 October 2023;  doi: 10.21926/obm.geriatr.2304253


Both from a healthcare and a socioeconomic perspective, research on senescence is increasingly essential. Indeed, in industrialized countries, the increased human longevity confronts medicine with many old patients with age-related pathologies. The paper reviews the biological theories on aging, the impact of reactive oxygen species, telomers, epigeneti [...]

Open Access Review

Screening and Treating Urinary Incontinence in Primary Care: A Missed Opportunity

Received: 12 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304252


More than 60% of adult women in the United States have urinary incontinence (UI), with the prevalence increasing to over 80% in women over age 65. Despite its high prevalence, most patients do not seek care and few clinicians screen for UI. The Medicare Health Outcomes Survey queries patients about satisfaction with their provider’s discussion and [...]

Open Access Review

Mixed Urinary Incontinence: Diagnosis and Management

Received: 17 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304251


The evaluation and treatment of mixed urinary incontinence receives relatively little attention as compared to other forms of incontinence. Mixed incontinence, however, defined as the combination of stress and urgency incontinence, accounts for the largest proportion of incontinence, with an increased incidence in older women. The condition can be ver [...]

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250


As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into [...]

Open Access Short Communication

Redefining Hypotension in Older Adults: Implications for the Prevention of Age Related Cognitive Decline

Received: 24 April 2023;  Published: 18 September 2023;  doi: 10.21926/obm.geriatr.2303249


Chronically low blood pressure in older adults is associated with significantly increased long-term risks of dementia and all-cause mortality risk. Yet low blood pressure is generally not treated until an individual begins to experience the acute symptoms arising from very low cerebral perfusion. However, these acute symptoms, such as dizziness, balance [...]

Open Access Editorial

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Received: 31 August 2023;  Published: 13 September 2023;  doi: 10.21926/obm.geriatr.2303248


In the United States (US), menopause occurs at an average age of 52. Menopausal symptoms tend to be maximal during the few years before and the year after menopause (during perimenopause), except for symptomatic vulvovaginal atrophy, which may worsen over time. Up to 20% of bone density loss occurs during the first 5 years after menopause, followed [...]

Open Access Opinion

Life-Changing Bubbles: A Simple Solution That May Help Many

Received: 20 February 2023;  Published: 24 August 2023;  doi: 10.21926/obm.geriatr.2303247


As the medical world continues to search for ways of improving the swallowing of many millions of Dysphagia sufferers around the world, this paper is devoted to presenting the case for carbonated water to be considered as a potential solution for many. The effectiveness of carbonated water (CW) in the rehabilitation of Dysphagia has been studied periodi [...]

Open Access Short Communication

US State Hospital Regulations Rarely Include Malnutrition but Could Provide a Future Policy Framework for Improving Malnutrition Quality of Care

Received: 31 March 2023;  Published: 17 August 2023;  doi: 10.21926/obm.geriatr.2303246


Malnutrition is a problem that is often not identified in hospitals as 8% of hospital patients are diagnosed but malnutrition is estimated to affect 20-50% of patients. Federal programs such as Joint Commission accreditation and the new, optional, global malnutrition composite score from CMS may improve inpatient malnutrition diagnosis, but there ma [...]

Open Access Research Article

Comprehensive Geriatric Assessment of Elderly Adults

Received: 23 March 2023;  Published: 14 August 2023;  doi: 10.21926/obm.geriatr.2303245


The geriatric population is increasing all over the world. Aging people have special health requirements and comprehensive medical checkups prevent physical, functional and mental decline during the aging period. This study aimed to examine the fitness level and identify problems with the well-being of elderly persons. In this context, the study also [...]

Open Access Perspective

Vascular Risks, Aging, and Late-Onset Dementia: Overlapping Etiologies Point to 'Scavenger Receptor'-Mediated Therapeutics

Received: 25 March 2023;  Published: 04 August 2023;  doi: 10.21926/obm.geriatr.2303244


Early changes in systemic vascular stiffness and endothelial function can contribute to altered cerebrovascular hemodynamics and impaired cognitive function; additionally, these vascular changes point to potential targets for prevention and treatment strategies in people with mild cognitive impairment. Although the pathogenic mechanisms underlying these [...]

Open Access Research Article

AI Literacy for an Ageing Workforce: Leveraging the Experience of Older Workers

Received: 02 March 2023;  Published: 25 July 2023;  doi: 10.21926/obm.geriatr.2303243


This study delves into the potential benefits of Artificial Intelligence (AI) literacy training for late-career-stage workers approaching retirement. These workers often possess extensive experience but may lack the necessary digital and AI skills. AI literacy training can empower them to leverage their experience and become proficient contributors [...]

Open Access Short Communication

Cross-Temporal Patterns of Care Provision by Older Adults during COVID-19 Pandemic: Lessons for Resilience

Received: 13 March 2023;  Published: 11 July 2023;  doi: 10.21926/obm.geriatr.2303242


The current study aimed to examine the link between cross-temporal patterns of care provision and loneliness in older adults. Social capital and caregiver stress perspectives served as a theoretical framework for the study. The data were obtained from the two COVID-19 waves of the Survey of Health, Ageing, and Retirement in Europe (SHARE) conducted [...]

Open Access Interview

An Interview with Dr. Ines Testoni

Received: 25 June 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302241


InterviewAn Interview with Dr. Ines TestoniOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2023, volume 7, issue 2 doi:10.21926/obm.geriatr.2302241Received: June 25, 2023Accepted: June 26, 2023Published: June 27, 2023

Open Access Case Report

Polymyalgia Rheumatica Evolved into RS3PE Syndrome. What is the Culprit: Idiopathic or Secondary, Following mRNA-Based COVID-19 Vaccines? A Case Report and Brief Review of the Literature

Received: 08 January 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302240


We describe the clinical case of a 74-year-old male patient who received the second Comirnaty/Pfizer anti-COVID-19 vaccine dose. After 3 weeks he showed the clinical signs of polymyalgia rheumatica. The history included mild chronic normocytic normochromic anemia and hypogammaglobulinemia, osteoarthritis disease, livedo reticularis, hypercholesterolemia [...]

Open Access Original Research

Role of Activity Professionals in Applying APIE Model to Enhance Residents’ Activity and Engagement in Long-Term Care Settings

Received: 23 August 2022;  Published: 25 June 2023;  doi: 10.21926/obm.geriatr.2302239


Residents’ activity is a strong contributor to the quality of life in long-term care facilities. Hence, activity professionals have an essential role to play in enhancing residents’ activity engagement. Professional practice model for activity professionals includes Assessment, Planning, Implementation, and Evaluation (APIE model). Although activit [...]

Open Access Original Research

The Geriatric Impact in the Management of Complex Cancer Patients: A Monocenter Experience

Received: 17 November 2022;  Published: 13 June 2023;  doi: 10.21926/obm.geriatr.2302238


New technologies, aging-related changes, and evolution in patients' needs have led to a new scenario in all oncological fields in front of which we have to move on. Technological progress has made it possible to increase the number of patients treated, including elderly patients and generally those at higher risk of toxicity. However, this scenario [...]

Open Access Communication

The Global Malnutrition Composite Score Quality Measure-Seize this Opportunity to Benefit Older Adult Care and Health Equity!

Received: 27 February 2023;  Published: 25 May 2023;  doi: 10.21926/obm.geriatr.2302237


In August 2022, the Centers for Medicare and Medicaid Services (CMS) adopted its first-ever nutrition electronic clinical quality measure (eCQM), known as the Global Malnutrition Composite Score (GMCS) as part of the Inpatient Hospital Quality Reporting (IQR) Program. Starting in January 2024, hospitals can self-select to include the GMCS as one of [...]

Open Access Review

The Effects of Loneliness on the Aged: A Review

Received: 09 November 2022;  Published: 17 May 2023;  doi: 10.21926/obm.geriatr.2302236


Social support has been shown to have many positive effects on our lives, health, and ability to grow and flourish. Lack, or diminished social support results in loneliness. This thematic review focuses on the elderly, and the loneliness that is part of the life of many of them. The review highlights the social connections and the expectations that [...]

2nd Mediterranean Congress of Anti-aging Medicine 2022

14–16 October 2022, Larnaca, Cyprus

This is the second time a conference with such a wide-ranging theme on aging is held in Cyprus. The 1st Mediterranean Congress of Antiaging Medicine was held in Larnaca on 13-14 April 2019. The health of older people is a crucial subject which involves a multidisciplinary approach in order to offer effective treatments against age-related diseases. The conference is comprehensive and practical, involving both basic science and clinical therapies. Lectures, presentations and seminars will be delivered by world-class academics, and by clinicians of European prestige. It will be attended by scientists working in the science of aging both from Cyprus and from Europe, Israel, Russia, United Kingdom, as well as clinicians, health professionals and others with interest in applied, effective interventions which may help reduce the impact of aging upon society. We expect wide media coverage as well as publicity reaching European, Asian and American countries.

For more information, visit the official website at: https://mcamcyprus.org/

26th World Congress on Medical Law

December 5th- 7th, 2022, Gold Coast, Australia

The purpose of the WAML is to encourage the study and discussion of health law, legal medicine and ethics, for the benefit of society and the advancement of human rights. The aim of the WAML is to promote the study of the consequences in jurisprudence, legislation and ethics of developments in medicine, health care and related sciences.

Congress Themes:

   1. Impact of Covid on Legal Medicine

   2. Medicine and technology

   3. Concussion and Traumatic brain injury

For more details, please visit: http://wafml.memberlodge.org/, http://lidsen.com/2022 WCML Brochure FINAL.

World CB & CDx 2022

April 27-28, 2022, London, UK

As the precision medicine industry witnesses exciting Drug-Dx approvals being driven by major advancements in biomarker development, the 12th Clinical Biomarker & CDx Summit Europe returns in 2022 to set the stage for key learnings with exclusive data to optimise your drug development programmes with the most cutting-edge tools and techniques from start to finish.

Against the backdrop of complex IVDR changes creating industry-wide uncertainty, CB & CDx Europe returns at an all-important moment in time as Europe’s only end-to-end clinical biomarker and CDx summit. Uniting the entire value chain of precision medicine leaders, here you can find the latest updates, intelligence and clarity to overcome your portfolio planning hurdles.

Delving deep into the most ground-breaking work enabling patient population identification, and pairing this with revelations from streamlined commercial strategies, this is an industry poised to gain actionable insights maximising access to game-changing precision medicines and testing technology in European markets.

Join with 300+ major stakeholders of the European drug-diagnostics field to forge successful scientific and commercialization co-development strategies at a pivotal moment for precision medicine.

For more details, please visit: https://cdx-europe.com/

Alzheimer's Association International Conference

July 31 – August 4, 2022, San Diego, USA and Online

Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.
For more details, please visit: https://www.alz.org/aaic/overview.asp

International Continence Society

September 07-10, 2022, Vienna, Australia

What to Expect at ICS 2022

ICS 2022 in Vienna will be a great 4-day meeting, offering a range of sessions and topics depending upon your speciality and interests.

The ICS annual meeting brings together the most renowned international experts in the research and the treatment of LUTS, incontinence and pelvic foor disorders. The meeting is multidisciplinary and welcomes urologists, gynaecologists, neurourologists, physiotherapists, nurses, midwives and research scientists.

ICS 2022 State of the Art Lectures and Round Table Debates

Expect to hear from world class leaders in the field of incontinence. Their lectures and discussions will bring you the cutting-edge information about pelvic floor dysfunction. We are pleased to confirm our 2022 State of the Art Lectures.

For more details, please visit:https://www.ics.org/2022

13th Clinical Trials on Alzheimer's Disease (CTAD)

November 4-7, 2020, Boston, USA

The development of the next generation of Alzheimer’s disease treatments is among the most important health needs worldwide, but presents huge challenges. The goal of the meeting is to bring together today’s worldwide leaders in the treatment of Alzheimer’s disease to discuss new results, candidate therapeutics, and methodological issues important to the development of the next generation of Alzheimer’s disease treatments.

Clinical trial teams from worldwide centers will report on their efforts to identify new biomarkers of disease as well as more sensitive clinical assessment tools to identify those at risk for AD, to predict progression, and assess the effectiveness of new treatments.

For more details, please visit: https://www.ctad-alzheimer.com/ctad-2020

Alzheimer's Association International Conference®

July 26-30, 2020, Amsterdam, Netherlands

AAIC 2020 will bring together international investigators, clinicians and care researchers to discuss the latest studies, theories and discoveries that will help bring the world closer to breakthroughs in dementia science.

For more details, please visit: https://www.alz.org/aaic/overview.asp

Integrative Regen Group

February 29- March 2, 2020, Arizona Biltmore Resort, USA

Who: Providers of all disciplines who are passionate about or interested in regenerative medicine are encouraged to attend this event. The agenda will be packed full of actionable topics that most attendees will be able to put into effect immediately to continue to provide their patients with the most cutting-edge therapies.

What: Integrative Regen Group’s second conference will be bringing together experts in all areas of regenerative medicine, from stem cells to photobiomodulation, peptides to hormones, and everything in between. It is our goal that every person in attendance increase their knowledge base substantially.

For more details, please visit: https://www.intregengroup.com/

The 2nd Longevity Therapeutics

January 28-30, 2020, San Francisco CA, USA

With rapid advances in the understanding of the underlying biology and mechanisms of aging, ground-breaking research and technology are coming together to target aging pathways, in a way to prevent, reverse or delay the onset of age-related conditions, and consequently improve heathspan.

The 2nd Longevity Therapeutics 2020 Summit will once again bring together 80+ leading experts in aging-related research, including biotechs, pharma, academics and investors, who are committed to serving worldwide population with innovative drugs to prevent, delay and treat age-related conditions.

For more details, please visit: https://longevity-therapeutics.com/

OBM Geriatrics welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.



by Michael Fossel

OBM Geriatrics 2023

Published: 15 January 2020

Highlight from: A unified model of dementias and age‐related neurodegeneration.

Michael Fossel.

Alzheimer’s & Dementia.

doi: 10.1002/alz.12012.

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