OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.


Archiving: full-text archived in CLOCKSS.

Publication Speed (median values for papers published in 2022): Submission to First Decision: 5 weeks; Submission to Acceptance: 14 weeks; Acceptance to Publication: 11 days (1-2 days of FREE language polishing included)

Current Issue: 2023  Archive: 2022 2021 2020 2019 2018 2017

Special Issue

Frailty in Older Adults: Issues and Challenges

Submission Deadline: September 15, 2023 (Open) Submit Now

Guest Editor

A. R. M. Saifuddin Ekram, Senior Clinical Research Consultant

ASPREE, SPHPM, Faculty of Medicine, Nursing and Health Sciences, Monash University, Australia

Website1 | Website2 | E-Mail

Research Interests: Frailty; Polypharmacy; Metabolic syndrome; Cardiovascular outcomes; Mortality

About This Topic

Multiple underlying physiological changes occur with increased aging, raising the likelihood of having chronic conditions, physical disabilities, and care dependency. Many older adults have one or more medical conditions that, when managed properly, have little impact on their overall well-being. Frailty, however, is linked to more adverse health outcomes, such as falls, trips to the hospital, and placement in long-term care facilities. Consequently, it becomes a barrier to healthy survival. For older people to age healthily, finding ways to slow down or reverse this condition may be essential through targeted interventions. This special issue, “Frailty in Older Adults: Issues and Challenges,” aims to connect researchers working in the field of frailty to foster our understanding of aging and its modulation by interventions.


Aging; Care dependency; Chronic conditions; Chronic inflammation; Frailty; Nutrition; Oxidative stress; Physical disabilities; Healthy survival