Use of Measuring Creatinine Kinase in Detection of Emerging Catatonia: Literature Review and Case Series Report







Abstract
(ISSN 2573-4407)
OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
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Use of Measuring Creatinine Kinase in Detection of Emerging Catatonia: Literature Review and Case Series Reportby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Catatonia, particularly malignant catatonia (MC), continues to manifest in severe sequalae such as hyperthermia, rhabdomyolysis, cardiovascular collapse and failure, and even death as, although identification of the syndrome has significantly improved once its developed, several precarious factors continue to inhibit prompt and efficacious treatment [...] |
A Case Study on the Development of Math Competence in an Eight-year-old Child with Dyscalculia: Shared Intentionality in Human-Computer Interaction for Online Treatment Via Subitizingby
![]() ![]() Abstract Studies in the field of neuroscience have shown that the neural network responsible for numeracy overlaps with the visual and spatial processing regions. Other studies in psychology also highlighted an association of visual-spatial processing with mathematical competence at the early stages of development. These findings suggest that research on the [...] |
Alcohol Withdrawal Induced Malignant Catatonia and Response to Bromocriptine: Case ReportAbstract Catatonia and malignant catatonia may result in devastating and life-threatening complications like pulmonary embolisms, pneumonia, deep venous thrombosis, rhabdomyolysis, and even death. There have been documented cases implicating alcohol withdrawal as a significant culprit in catatonia. Here, we provide a unique case report of a patient with a compli [...] |
Cerebral Palsy: An Overview of Etiology, Types and Comorbiditiesby
![]() Abstract Cerebral Palsy (CP) is the most frequent cause of childhood disability. CP occurs in 1 out of every 345 children in the United States. CP is primarily a motor disease that is the result of an insult to the brain that occurs during the prenatal or early postnatal period when the brain is still developing. CP is not a single disease but a physical descrip [...] |
Examining the Social Signaling and Person Perception Functions of LonelinessAbstract Loneliness is a common condition that poses substantial risks to morbidity and mortality. Cacioppo and Cacioppo’s [1] evolutionary theory of loneliness (ETL) provides that loneliness serves a social signaling function and also manifests in hypervigilance to threat, which we propose can influence person perception. In this experiment, 480 observers [...] |
An Interview with Dr. Roy G. BeranAbstract InterviewAn Interview with Dr. Roy G. BeranOBM Neurobiology Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: neurobiology@lidsen.comOBM Neurobiology2022, volume 6, issue 2doi:10.21926/obm.neurobiol.2202118Received: April 02, 2022Accepted: April 02, 2022Published: April 07, 2022 |
Arterial Elasticity: Linking of Cardiovascular Risks, Pulse Pressure, Dementia, Aging, and Drug TargetingAbstract Cerebrovascular atherosclerosis, and several other cardiovascular (or "inflamm-aging" type) diseases, are more frequent and advanced in subjects with Alzheimer's disease compared with normal aging. In addition, the observed pathogenic link to dementia (and its associated cerebral microvascular damage) is readily explained by alterations of arterial [...] |
Neuropathology and Therapeutics Addressing Glaucoma, a Prevalent Retina-Optic Nerve-Brain Disease that Causes Eyesight Impairment and BlindnessAbstract Glaucomatous optic neuropathy (GON) associated with different forms of glaucoma and chronic ocular hypertension (cOHT) is characterized by progressive loss of retinal ganglion cells and their axons in the optic nerves that project to the brain to transmit visual information. The resultant thinning of the optic nerves cause loss of peripheral vision [...] |
Analysis of Migraine Pathophysiology by Magnetic Resonance ImagingAbstract Magnetic resonance imaging (MRI) has been used to investigate migraine pathophysiology because it is a non-invasive technique. The main aim of clinical imaging for patients with headaches is to exclude secondary headaches due to organic lesions. Conventional structural imaging techniques such as routine MRI demonstrate white matter lesions, changes [...] |
Acknowledgement to Reviewers of OBM Neurobiology in 2021Abstract The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...] |
Neuronal Coherence Agent for Shared Intentionality: A Hypothesis of Neurobiological Processes Occurring during Social Interactionby
![]() ![]() Abstract The present interdisciplinary study discusses the physical foundations of the neurobiological processes occurring during social interaction. The review of the literature establishes the difference between Intentionality and Intention, thereby proposing the theoretical basis of Shared Intentionality in humans. According to the present study, Shared Inten [...] |
The Potential Impact of COVID-19 on Depression and Suicide Risk in Older AdultsAbstract COVID-19 infections, hospitalizations, and deaths continue to skyrocket across the world, leaving a trail of enduring psychological turmoil. It wreaks havoc on the physical, emotional, and cognitive health of those directly infected, as well as caretakers, friends, and families. Though the pandemic has at least indirectly impacted most people, older [...] |
Effects of Circadian Rhythm on Migraine Therapyby
![]() ![]() Abstract Circadian rhythms are 24-hour cycles of physical, mental, and behavioral changes regulated and maintained by the internal primary circadian clock, however modifiable by a number of external cues or “zeitgebers”, the most powerful one being light. Core set of clock genes regulate the whole-body metabolism and transcription of over 40% of mammalian [...] |
The Relationship between Sensory Reactivity Differences and Mental Health Symptoms in Children with Neurodevelopmental Conditions and Their Neurotypical PeersAbstract Children with neurodevelopmental conditions (NDC) often have sensory reactivity differences, such as being overwhelmed by sounds, which can elicit distress in their everyday life. Furthermore, children with an NDC often present with a greater frequency of mental health symptoms compared to their typically developing peers. However little research has [...] |
Narrative Review of Surgery for Myasthenia GravisAbstract Myasthenia Gravis (MG) is a rare autoimmune disorder characterized by antibody mediated blockade of neuromuscular transmission. Up until the last decade, evidence suggesting benefit of thymectomy for myasthenia gravis has been based on non-randomized control studies. Our paper serves as an expert narrative review of new literature pertaining to surgical [...] |
Antidepressant Treatment of Depression in the Elderly: Efficacy and Safety ConsiderationsAbstract Depression in the elderly is a significant clinical problem which is likely to endure as an ongoing issue as the cohort of individuals aged over 65years continues to increase as a proportion of the total population. While there are a multiplicity of approaches to the treatment of depression, the mainstay for moderate to severe cases is pharmacotherap [...] |
Neural Response to High and Low Energy Food Images in Anorexia Nervosaby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract To compare neural responses to high and low-energy food images in patients with Anorexia Nervosa (AN) and an age-matched Healthy Control (HC) group. 25 adolescents with AN and 21 HCs completed a diagnostic interview, self-report questionnaires and fMRI, during which they viewed food images evoking responses of disgust, happiness, or fear. Following [...] |
Innovative Strategies and Challenges for the Prevention of Pathological Anxiety in Children and AdolescentsAbstract The effects of pathological anxiety on public health have led to the realization that anxious children might experience significant limitations in their lives. Evidence-based cognitive-behavioral (CB) interventions are now being implemented in schools at a group level to combat anxiety.Childhood emotional health should be considered a national and globa [...] |
Single-Case Neuropsychological Assessment of a Patient with a Posterior Parietal Lesion Using Behavioral Testing and Resting-State fMRIby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract This study integrated functional connectivity measures using resting-state fMRI and behavioral data from a single-case observation of patient (PER) one year after right-hemispheric hemorrhage in the intraparietal sulcus and superior parietal lobule (IPS/SPL). PER showed no sign of clinical neglect. Her behavioral performance in the visuo-manual pointing [...] |
Genetic, Social and Behavioral Risk Factors Associated with Alzheimer’s DiseaseAbstract Alzheimer’s disease (AD) is a neurodegenerative condition which consists of stages of mental, memory, and cognitive decline. As it continues to stand as the sixth leading cause of death in the U.S., 44 million people worldwide are affected. The objective of this paper is to explore the risk factors for AD in an attempt to examine potential causes [...] |
Why the Quantum Brain?Abstract This article reviews the modern approaches to the quantum brain hypothesis. The aim is to consider the hypothesis and its classical brain-machine alternative from a broad perspective, including physics, biology, computer science, cosmology, and metaphysics. My starting point is that asking whether consciousness can or cannot have free will is fundamenta [...] |
Psilocybin as a Novel Pharmacotherapy for Treatment-Refractory Anorexia NervosaAbstract Anorexia Nervosa (AN) is a major health problem with one of the highest mortalities and treatment costs of any psychiatric condition. Cognitive behavioural therapy (CBT) is currently the most widely used treatment for AN in adults but provides remission rates ≤ 50%. Treatment drop-out is exceedingly high and those that persevere with treatment often [...] |
Establishing and Evaluating a Multidisciplinary Community-Based Sleep Clinic for Children with Neurodevelopmental Difficulties in Inner LondonAbstract We describe our experience of setting up and evaluating a community-based multi-disciplinary sleep service for children with neurodevelopmental disorders and psychosocial vulnerabilities.Referrals are accepted for children (1-18 years of age) with persistent sleep problems, and neurodevelopmental difficulties or significant psychosocial adversity, livin [...] |
The Trails Making Test. Does a Single Trial Reflect Performance Capability?Abstract Information processing speed (Reaction time, RT) to a single administration of the Trails A and Trails B components of the Trail Making Test (TMT) is used in the assessment of brain and behavioural functional integrity across the lifespan in both clinical and research contexts. Although the clinical utility of such single trial-related and thus rapidl [...] |
Management of Agitation, Delirium, and Catatonia in Intubated COVID-19 Patients: A Case Series & Rationale for Valproate Sodium Use During Extubationby
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract The complete spectrum of neuropsychiatric effects of SARS-CoV-2 acute respiratory distress syndrome has yet to be fully appreciated, particularly in intubated patients. Manifestations including delirium and catatonia need to be considered in intubated COVID-19 patients. Medications known to exhibit neuroprotective effects, like valproate, can assist [...] |
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OBM Neurobiology 2022
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