OBM Neurobiology

(ISSN 2573-4407)

OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

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Publication Speed (median values for papers published in 2024): Submission to First Decision: 7.6 weeks; Submission to Acceptance: 13.6 weeks; Acceptance to Publication: 6 days (1-2 days of FREE language polishing included)

Open Access Case Report

Forgiveness Therapy to Reduce Violent Behavior in Individuals with Schizophrenia: A Case Study

Received: 03 December 2024;  Published: 26 March 2025;  doi: 10.21926/obm.neurobiol.2501281

Abstract

This study aims to describe the application of forgiveness therapy as a psychosocial intervention for a schizophrenia patient with violent behavior. Mr. M, a 19-year-old male diagnosed with schizophrenia, exhibited psychotic symptoms, including auditory hallucinations, persecutory delusions, agitation, and aggression. He had a history of trauma due [...]

Open Access Research Article

Do We Care about Preschool Children's Leisure Time? Correlations between Anxiety Symptoms and Leisure Time Allocation. Results of a Cross-Sectional Study

Received: 06 January 2025;  Published: 24 March 2025;  doi: 10.21926/obm.neurobiol.2501280

Abstract

Children's leisure time in the Western world is changing compared to what it used to be in the previous decades. Children's involvement in organized activities and screen time use is increasing, while outdoor play, despite once being the main leisure time activity for children, is declining. Gray, Oliver and other contemporary theorists link this shift [...]

Open Access Review

Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Abstract

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgica [...]

Open Access Review

The Independence Principle - A Neglected Feature of the Hodgkin Huxley Legacy

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

Abstract

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental [...]

Open Access Review

Neurotoxicity Following Exposure to Micro and Nanoplastics

Received: 13 December 2024;  Published: 16 March 2025;  doi: 10.21926/obm.neurobiol.2501277

Abstract

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although [...]

Open Access Original Research

A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Abstract

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics [...]

Open Access Original Research

Studying the Cognitive and Behavioural Dynamics of Psychopathy

Received: 04 December 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501275

Abstract

The relevance of studying the cognitive and behavioral dynamics of psychopathy lies in its importance for improving diagnosis, therapeutic interventions, and reducing crime, thereby contributing to public safety. This study aimed to investigate how cognitive and behavioral mechanisms influence psychopathy. A combination of methods was employed, includin [...]

Open Access Original Research

A Pilot Double-Blind Randomised Sham-Controlled Trial of Paraesthesia-Free Burst Waveform Spinal Cord Stimulation in a Small Case Series of Patients with Chronic Spinal or Limb Pain

Received: 24 November 2024;  Published: 05 March 2025;  doi: 10.21926/obm.neurobiol.2501274

Abstract

The aim of this study was to identify methodological issues that might influence comparison of burst versus sham spinal cord stimulation for treating chronic pain. Six patients with an implanted BurstDR spinal cord stimulator were assessed double-blind during eight 3-to-4-day ON or OFF cycles over a 28-day period. The stimulator was switched off during [...]

Open Access Review

The Impact of Microbiota on Neurological Disorders: Mechanisms and Therapeutic Implications

Received: 06 November 2024;  Published: 28 February 2025;  doi: 10.21926/obm.neurobiol.2501273

Abstract

Interactions in the gut-brain crosstalk have led to the development of an entirely new concept: the "microbiota-gut-brain axis". Microbiota has gained considerable attention in relation to disorders of a more neurological nature, such as neurodevelopmental and neuropsychiatric illnesses like autism spectrum disorder, anxiety, and mood disorders. This [...]

Open Access Review

Therapeutic Exercise Holds the Key to Improve Hand and Upper Limbs Dystonia Rehabilitation Programs: A Systematic Review

Received: 20 September 2024;  Published: 27 February 2025;  doi: 10.21926/obm.neurobiol.2501272

Abstract

Upper limb dystonia is a focal locomotion disorder affecting arm, forearm, and hand muscles, causing abnormal movements given by repeated, steady, and intercontinuous contractions. There are different types of dystonia and the multifaced nature of this pathology is challenging in the treatment management, leading to a worsening of affected patients [...]

Open Access Original Research

Digital Technology and Brain Development among Entrepreneurial Ambitions

Received: 20 October 2024;  Published: 25 February 2025;  doi: 10.21926/obm.neurobiol.2501271

Abstract

Brain development (BD) is an important factor. To effectively enhance BD, institutions employ digital tools, technology, and innovative digital competencies to improve students’ entrepreneurial ambitions. The present paper examines the role of digital technology in developing BD among entrepreneurial ambitions in Egypt. The study modes are quantitativ [...]

Open Access Original Research

The Role of E-Learning Crack-Up Perception and Fear of Academic Year Loss in Students’ Psychological Distress and Academic Performance

Received: 27 October 2024;  Published: 14 February 2025;  doi: 10.21926/obm.neurobiol.2501270

Abstract

This study examines the effect of e-learning crack-up perception (ECUP) and fear of academic year loss (FAYL) on psychological distress (PD). The study also explores the impact of PD on students' academic performance (AP). It uses a quantitative method based on data collected from Egyptian medical university students using convenience sampling. The [...]

Open Access Opinion

Understanding the Scope of the Contemporary Controversy about the Physical Nature and Modeling of the Action Potential: Insights from History and Philosophy of (Neuro)Science

Received: 09 October 2024;  Published: 13 February 2025;  doi: 10.21926/obm.neurobiol.2501269

Abstract

According to mainstream neuroscience, the action potential (AP) is a purely dissipative electrical phenomenon that should be modeled as such. However, also (essentially) reversible mechanical, thermal, and optical changes in the neuron have been reported to accompany the movement of the AP along the axonal surface. These are not accounted for in the [...]

Open Access Original Research

A New Technology System to Support Occupational Activity and Mobility in People with Severe-to-Profound Intellectual Disability and Blindness

Received: 14 October 2024;  Published: 12 February 2025;  doi: 10.21926/obm.neurobiol.2501268

Abstract

People with severe-to-profound intellectual disability and blindness tend to be sedentary and detached, given their orientation and mobility problems, often combined with their limited interest in their surroundings. An approach to address this problem may involve the use of technology systems guiding the participants through mobility and occupational [...]

Open Access Original Research

Measuring Post-Exertional Malaise with DePaul Symptom Questionnaires: Challenges and Opportunities

Received: 15 October 2024;  Published: 05 February 2025;  doi: 10.21926/obm.neurobiol.2501267

Abstract

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM [...]

Open Access Research Article

Exploring the Unidimensionality of the GAD-7 for South African First Responders: Evidence from Multiple Psychometric Approaches

Received: 21 September 2024;  Published: 27 January 2025;  doi: 10.21926/obm.neurobiol.2501266

Abstract

Generalized Anxiety Disorder (GAD) is a prevalent mental health condition and the GAD-7 is widely used as a screening tool and measure of GAD severity. However, research has yielded conflicting findings regarding the factor structure of the instrument, with some studies supporting a unidimensional interpretation while others suggest a two-factor solutio [...]

Open Access Review

Advancements in Silkworm-Derived Silk Fibroin Biomaterials for Peripheral Nerve Regeneration

Received: 14 October 2022;  Published: 20 January 2025;  doi: 10.21926/obm.neurobiol.2501265

Abstract

Regenerating injured nerves is difficult because they have little spontaneous regeneration potential. Advances in tissue engineering and regenerative medicine have emphasized the possibility of biomaterial-based methods for nerve healing. Natural protein-based biomaterials have benefits over synthetic ones, such as biocompatibility, non-immunogenicit [...]

Open Access Review

Unraveling the Impact of Modern Technologies on Young Minds: A Comprehensive Study

Received: 22 October 2024;  Published: 13 January 2025;  doi: 10.21926/obm.neurobiol.2501264

Abstract

The implementation of modern technologies has transformed connectivity, information-sharing, and education, significantly influencing students' academic journeys. New technologies offer advantages and disadvantages, particularly impacting young students and leading to changes in habits and behaviors. While technology can improve learning efficiency [...]

Open Access Review

Reflexes and Shared Intentionality in the Origins of Emotions Development: A Scoping Review of Studies on Blinking in Infants

Received: 16 August 2024;  Published: 10 January 2025;  doi: 10.21926/obm.neurobiol.2501263

Abstract

This review aims to explore research on the development of emotions in organisms at the simple reflexes substage of the sensorimotor stage of cognitive development. We review the literature on alterations in spontaneous blinking in children under 6 months of age. Then, we extract the data from the selected studies that allow us to examine whether simple [...]

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2024

Received: 03 January 2025;  Published: 03 January 2025;  doi: 10.21926/obm.neurobiol.2501262

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...]

Open Access Review

The Impact of Depressive and Anxiety Symptoms on Academic Achievement among Undergraduate University Students: A Systematic Review

Received: 21 October 2024;  Published: 31 December 2024;  doi: 10.21926/obm.neurobiol.2404261

Abstract

Numerous studies have explored the prevalence of depression and anxiety symptoms among university students worldwide. However, only a few have examined how these symptoms affect students' academic performance. This systematic review explores the relationship between depression, anxiety, and academic performance among undergraduate university students [...]

Open Access Review

The Origin of Natural Neurostimulation: A Narrative Review of Noninvasive Brain Stimulation Techniques

Received: 08 September 2024;  Published: 29 November 2024;  doi: 10.21926/obm.neurobiol.2404260

Abstract

This narrative review of the literature on noninvasive brain stimulation techniques observes four neurostimulation domains: light therapy, photobiomodulation, a group of techniques within transcranial electric current and magnetic field stimulations, low-frequency sound stimulations, including vibroacoustic therapy, and rhythmic auditory stimulation [...]

Open Access Original Research

Factor Structure of Autism Symptoms in 5-6-Year-Old Children: Age Perspective

Received: 03 July 2024;  Published: 27 November 2024;  doi: 10.21926/obm.neurobiol.2404259

Abstract

The work identifies the factor structure of autism symptoms in older preschoolers to check their age dynamics. An Autism Marker Questionnaire containing 330 potential symptoms of autism spectrum disorder (ASD) was developed to be implemented as an online survey. 501 children were examined (371 with ASD) already classified by experts as a group of ASD [...]

Open Access Review

Frontal Migraine Surgery: Indications and Results

Received: 18 July 2024;  Published: 27 November 2024;  doi: 10.21926/obm.neurobiol.2404258

Abstract

Recent studies have identified that certain types of migraines, including frontal migraines, may be attributed to the irritation of specific extracranial nerves. This systematic review addresses the following questions: Which surgical techniques are most effective for chronic frontal migraines? How do combined surgical approaches compare to isolated [...]

Open Access Review

Evaluating the Efficacy of Action Observation Training in Improving Upper Limb Functionality in Children with Cerebral Palsy: A Scope Review

Received: 02 June 2024;  Published: 22 November 2024;  doi: 10.21926/obm.neurobiol.2404257

Abstract

This review evaluates the efficacy of Action Observation Training (AOT) in improving upper limb functionality in children with cerebral palsy (CP). Five studies were selected based on strict inclusion criteria, focusing on clinical interventions that assessed AOT's effects on upper limb motor skills in pediatric CP populations. Across these studies [...]

Historical Announcements

Update: Article Processing Charge (Price Changes Effective January 1, 2025) 2024-10-21

OBM Neurobiology welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.

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2023
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Update: Article Processing Charge (Price Changes Effective January 1, 2025)

The journal OBM Neurobiology (ISSN: 2573-4407) will have the new APCs (New APC, 950 USD) for manuscripts submitted after 31 December 2024.

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