OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes research articles, technical reports and invited topical reviews. Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 11.8 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).

Current Issue: 2023  Archive: 2022 2021 2020 2019 2018 2017

Special Issue

Surgical Therapy for Migraine and Tension-Type Headache

Submission Deadline: July 31, 2023 (Open) Submit Now

Guest Editor

Edoardo Raposio, PhD, MD, FICS, Professor

Director, Plastic Surgery Chair and Residency Program, University of Genova, Italy Chief, Plastic Surgery Division, San Martino Hospital, Genova, Italy

Website | E-Mail

Research interests: Plastic and Reconstructive Surgery; Migraine Surgery; Regenerative Medicine; Endoscopic Mininvasive Surgery; Stem Cells. 

About This Topic

Migraine headache (MH) is a common disorder affecting over 324.1 million people world wide, which can seriously decrease quality of life and work productivity of the patients. It is estimated that in the USA 37 million people suffer from MH, which is equal to 12% of the total population. The situation is similar in Europe, where more than 50% of adults reported at least one episode of headache during the last year and about 4% of the total population suffers from chronic headache. Furthermore, some studies indicate that the headache prevalence is increas ing during the last decades in Europe. MH represents also a social and economic burden. In the USA, the total cost for MH treatment accounts for $13–17 billion each year and 112 million of missed workdays with an indirect loss of $13 billion. Despite its prevalence and debilitating nature, MH is still widely undiagnosed and undertreated. The first approach is usually a combination of pharmacologic treatments (both abortive and preventive drugs) and non-pharmacological interventions like behavioural and lifestyle changes. Despite all the available conservative options, a quite relevant group of MH patients remains refractory and does not achieve a satisfactory relief. The idea to treat MH refractory patients with a surgical procedure is relatively new. In recent years, further evidences and anatomical studies were determinants to validate the surgical approach. Although the pathophysiology of MH remains a matter of discussion, it seems evident that nerve compression in some specific areas plays a pivotal role in triggering MH episodes. The aim of this Special Issue is to investigate and describe the currently available surgical options to treat MH. Relevant anatomical issues are also reviewed as well as their implications in the surgical treatment.


Migraine, Tension-type Headache; Migraine Surgery; Tension-type Headache Surgery.