Table of Content

Open Access Review

Effective Physiotherapy for Post-Concussion Recovery and Return to Sports: Narrative Review

Received: 30 August 2024;  Published: 20 November 2024;  doi: 10.21926/obm.neurobiol.2404255

Abstract

Traumatic brain injury (TBI) caused by direct or indirect forces is a prevalent issue in contact sports, leading to symptoms such as headaches, dizziness, nausea, and neck pain. These symptoms can have long-term consequences, including neurodegenerative diseases and mood disorders. This review fills an essential gap in the literature, as current studies on physiotherapy for traumatic brain injury (TBI) in sports are limited in scope, particularly in evaluating multimodal and personalized interventions. The review a [...]

24 136

Open Access Review

Gut Microbiota and Neuroinflammation: An Interconnected Nexus of Health and Neurodegenerative Disease

Received: 08 June 2024;  Published: 20 November 2024;  doi: 10.21926/obm.neurobiol.2404254

Abstract

The gut microbiota, a complex ecosystem of billions of microorganisms in the human digestive tract, plays a crucial role in maintaining health. Recent studies have highlighted a bidirectional communication pathway called the gut-brain axis between the gut and the brain. This communication is significantly influenced by gut microbiota and its interactions with the immune system, which can affect brain function and contribute to inflammation. This study aims to provide a comprehensive overview of the relationship bet [...]

28 143

Open Access Original Research

The Development of Operational Model Integrating Digital Technologies into Public Mental Healthcare Services in Nigeria

Received: 09 July 2024;  Published: 08 November 2024;  doi: 10.21926/obm.neurobiol.2404253

Abstract

The availability and utilization of digital technologies can leverage the challenges of the sharp-depleting workforce due to the consistent migration of healthcare professionals (HCPs), the alarming ratio of the number of patients to HCPs, discretional use of digital technologies among HCPs in providing effective therapeutic interventions and mental healthcare services. This study aimed to develop an operational model that integrates digital technologies in mental healthcare service delivery for public facilities i [...]

44 458

Open Access Review

Relationship of Retroelements with Antiviral Proteins and Epigenetic Factors in Alzheimer's Disease

Received: 10 August 2023;  Published: 31 October 2024;  doi: 10.21926/obm.neurobiol.2404252

Abstract

Genetic factors such as allelic variants of the PSEN1, PSEN2, APP, and APOE genes play an important role in Alzheimer's disease development. Still, they cannot explain all cases of the disease and cannot form the basis for effective treatment methods for the pathology. Alzheimer's disease is the most common neurodegenerative disease, so identifying new mechanisms of pathogenesis may reveal new ways of treating it. Since Alzheimer's disease is associated with aging, the hypothesis is proposed that an important trigg [...]

53 506

Open Access Review

The Relationship between Emotional Intelligence and Bullying in Adolescents: A Scoping Review

Received: 21 July 2024;  Published: 25 October 2024;  doi: 10.21926/obm.neurobiol.2404251

Abstract

Bullying is a serious problem among adolescents with broad negative impacts on psychological and social well-being. Factors that influence bullying are individual and environmental. Emotional intelligence has been identified as an essential factor influencing bullying behavior, but its relationship is not fully understood. This research aims to conduct a scoping review of the relationship between emotional intelligence and adolescent bullying behavior. A scoping review approach was used in this research. Search for [...]

95 741

Open Access Original Research

Predictive Effect of Eco-Anxiety and Climate Change Anxiety towards Mental Health Problems and Psychological Well-Being among Entrepreneurs

Received: 25 July 2024;  Published: 18 October 2024;  doi: 10.21926/obm.neurobiol.2404250

Abstract

Entrepreneurs face massive challenges when attempting to create sustainable businesses in the current era. This juggling act leads to eco-anxiety and climate change anxiety, which mainly affect entrepreneurs by creating concerns and ruining creativity and progress. These issues contribute to individuals' mental health problems (MHP) and severely affect psychological well-being (PWB). With this in mind, the present study investigates the impact of eco-anxiety (EA) and climate change anxiety (CCA) on MHP and PWB amon [...]

73 693

Open Access Case Report

Stuart Stress Adaptation and Nola Pender's Model on Mental Nursing Care of Patients Schizophrenia: Case Study

Received: 20 July 2024;  Published: 12 October 2024;  doi: 10.21926/obm.neurobiol.2404249

Abstract

To describe the application of the Stuart Stress Adaptation and Nola Pender Models in mental nursing care for a patient with schizophrenia and risk of violent behavior. This research method used case studies. The sample is one patient with schizophrenia. Data collection is done through direct observation, interviews, and patient medical records. The results showed that the client showed a major nursing problem in the form of risk of violent behavior. Predisposing factors included passive childhood experiences and s [...]

100 828

Open Access Review

Effectiveness of Integrating Botulinum Toxin Type A with Rehabilitative Strategies for Managing Spastic Diplegia in Children: Scope Review

Received: 31 May 2024;  Published: 10 October 2024;  doi: 10.21926/obm.neurobiol.2404248

Abstract

This review examines the effectiveness of integrating botulinum toxin type A (BONT-A) with various rehabilitative strategies in treating spastic diplegia in children. The studies analyzed consistently demonstrate significant reductions in spasticity and improvements in gait when BONT-A is combined with interventions such as intensive physical therapy, serial casting, electrical stimulation, physiotherapy, occupational therapy, and robotic-assisted gait training. The findings underscore the importance of personalize [...]

68 685

Open Access Original Research

A Probiotic Mixture Decreases Neuropathy and Oxidative Stress Markers in Diabetic Rats

Received: 11 May 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403247

Abstract

Diabetic neuropathy (DN) is a type of nerve damage caused by long-term hyperglycemia in diabetes mellitus (DM). The gut microbiota alters in DM. Therefore, improvement of the gut flora may affect neuropathic pain and oxidative biomarkers' responsiveness to the probiotic treatment. The present study aimed to assess the effects of probiotic supplementation on neuropathic pain and oxidative stress biomarkers in diabetic rats’ serum. Forty-eight rats (200-250 g) were randomly divided into four groups (n = 12 per group) [...]

78 585

Open Access Original Research

Breaking Barriers: A Reliable Method for RNA Extraction in Zebrafish Neurodegenerative Research

Received: 02 June 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403246

Abstract

Zebrafish (Danio rerio) is a vertebrate with unique characteristics, making it an excellent biomedical research animal model. One research area involves investigating changes in gene expression during neurodegenerative processes, aging-related changes, and behavioral studies in zebrafish. To achieve this, high-quality and quantity RNA must be extracted from zebrafish. This study aims to develop an optimized RNA extraction method from zebrafish larvae brains. After rearing and maintaining the zebrafish in suitable c [...]

84 665

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