OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
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Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.7 weeks; Submission to Acceptance: 17.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Oral and Pharyngeal Hypofunction, Malnutrition and Frailty
Submission Deadline: September 30, 2024 (Open) Submit Now
Mari Nakao-Kato, MD, PhD, Professor
Director of Health Center
Leader of IDDSI Reference Group Japan
Division of Health and Nutrition, Tohoku Seikatsu Bunka University, Sendai, Japan
Research Interests: Dysphagia, Rehabilitation for swallowing disorders, Stroke, Sarcopenia, Nutrition
Roberta Gasparro, PhD
Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II
Research Interests: Bioengineering; Implantology; Stem cells; Hemocomponents
About This Topic
In recent years, research on frailty has grown considerably, and it has become clear that physical frailty is strongly associated with social and psychological frailty.
Oral frailty is unique among these because it shows a strong association with oral intake and nutritional status. In fact, malnutrition and reduced physical function are both considered as elements of frailty cycle. Although data on the oral hypofunction in the elderly have been accumulating in recent years, further research is needed to determine the impact of the oral frailty on dysphagia, how it may affect nutritional status and physical function.
This special issue aims to include the latest research on oral and pharyngeal hypofunction (e.g. presbyphagia), malnutrition, and frailty in the elderly. Pathophysiology of oral frailty in the elderly and intervention strategies to maintain and improve oral and pharyngeal function, the interaction between nutritional intake and oral and physical health in the elderly, and the impact of socioeconomic factors related to the oral frailty of the elderly will be addressed. We encourage clinicians and scientists in the field to submit original articles or reviews that align with these goals.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (firstname.lastname@example.org) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
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