OBM Geriatrics is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.7 weeks; Submission to Acceptance: 17.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Special Issue
Sleep Disorders in Older People
Submission Deadline: September 15, 2020 (Open)
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Guest Editor
Roy G. Beran, MD
Conjoint Professor, Department of Medicine, University of New South Wales, Sydney, Australia;
Professor, School of Medicine, Griffith University, Nathan, Queensland, Australia;
Professor, Chair, Medical Law, Sechenov Moscow First State University, Moscow, Russia
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Research Interests: Sleep; health law & ethics; epilepsy; sleep disorders; drug trials; legal medicine; neurological conditions & new therapies; neurological advances
About This Topic
"Sleep Disorders in the Elderly" is a broad ranging topic that largely encompasses all of geriatric medicine as well as the neurology of the elderly. Those dealing with older patients are usually either geriatricians or neurologists, rather than sleep physicians. Almost no geriatricians and very few neurologists are cross-accredited with appropriate training in sleep medicine. As a consequence, this relegates consideration of sleep-related disorders to the periphery of patient evaluation, despite such conditions as obstructive sleep apnoea (OSA) having the potential to result in significant increase in stroke, myocardial infarction and dementia. Restless legs and Periodic Limb Movements In Sleep (PLMS), often with arousal (PLMA), respond to anti-Parkinsonian agents, such as dopamine agonists, such as Pramipexole, raising consideration that dopamine agonists have a therapeutic role in a number of sleep disorders.
As people age, so there is a comparable increase in sleep related disorders, such as OSA. With age often comes increased affluence, obesity and related issues of which OSA is just one of many. Degenerative diseases, such as Parkinson's Disease (PD), also increase in prevalence with advancing age. PD is associated with a number of sleep-related problems, including REM Behaviour Disorder (RBD) as well as OSA.
With the growing appreciation of the ubiquitous impact of sleep-related problems, particularly amongst the elderly, it has been appreciated that there is an unmet need to provide an educative resource to help those involved in the management of the elderly to enhance better management of their sleep disorders.
Because of the impact of Continuous Positive Air Pressure (CPAP) OSA, in many countries, such as Australia, has been usurped by respiratory physicians to the point that the Australian Health Practitioner Registration Agency/Authority does not cross-accredit either geriatricians or neurologists as sleep physicians and only categorises sleep medicine within the rubric of respiratory and sleep medicine, ignoring the fact that OSA was first diagnosed by neurologists when investigating patients thought to have epilepsy with all night video telemetric electroencephalography. It follows that there are a number of biases involved in the management and recognition of sleep medicine, which has greater relevance in the elderly, and it is envisaged that this focused issue of the Journal will address at least some of those unmet needs.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (geriatrics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
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Publication
Abstract
This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which [...]
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Open Access
Research Article
Abstract
Insomnia and excessive daytime sleepiness are the most common sleep disturbances in Parkinson’s disease. This study aims at better understanding how severity of PD motor and non-motor features and dopaminergic treatments contribute to these sleep symptoms in the first decade of PD. Data from a community-based cohort of PD patients was used [...]
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Roy G Beran
Vidhi is a Clinical yoga therapist; mentor for yoga therapy training in Krishnamacharya tradition. She holds a MSc in Public health from Kings College London.
Mirela Olympia Fagarasan Palmer
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Zhong-Ting (Justin) is a PhD student from Nanyang Technological University (Singapore). He holds BSc in Applied Chemistry and MSc in Environmental Engineering. He was a R&D researcher of NanoMaterials Technology Pte Ltd in Singapore (2006-2012). His current research interests are functional nanomaterials synthesis & design, and their application into environmental/chemical engineering. He has published near 60 SCI papers in Applied Catalysis B, Chemical Engineering Journal and so on with H-Index 23. He also serviced as reviewers over 40 Journals such as Appl. Catal. B, Water Research, Chem. Eng. J, ACS Applied Materials & Interface, etc. He was honored such as “The Bsic Research Achievment 1st Award of CIESC”, “The ZJUT Fund Breeding Distinguished Young Scholars” etc.
Rolf Teschke studied Medicine in Munich and Marburg, where he finished his MD thesis before starting a residency at the Department of Pathology, University of Marburg. Subsequently and with a fellowship of the Deutsche Forschungsgmeinschaft, he worked at the Bronx VA Hospital/Mount Sinai Hospital in New York during 1972–1975 together with Professor Charles S. Lieber and successfully isolated MEOS and expanded its characterization. Back in Germany, he was at the Heinrich-Heine University in Düsseldorf with a focus on alcoholic liver disease, biochemical drug studies, and clinical intoxications by halogenated aliphatic hydrocarbons, where he became a Professor of Medicine. In 1987, he was offered a chief position and appointed as Director of the Medical Department II, City Hospital Hanau, Teaching Hospital of the Johann Wolfgang Goethe University Frankfurt/Main. His clinical and research interests are on liver injury by drugs and herbs including causality assessment by RUCAM in close association with Dr. Gaby Danan in Paris. A perfect cooperation exists also with Professor Tran Dang Xuan of the University of Hiroshima, Japan. Finally, he is the author of more than 275 publications including books and book chapters, and he is editor in chief of scientific journals and member of editorial boards.