Current and Future Applications of Machine Perfusion and Other Dynamic Preservation Strategies in Liver TransplantationAbstract Machine perfusion (MP) techniques, which simulate physiological conditions to allow for the assessment and preservation of organ viability, are currently applied in various solid organ transplantation fields. Owing to the growing demand for liver transplants and [...] 28 182 |
Platelets as Regenerative Cells, Hundreds of Opportunities in SightAbstract Platelets were the last to be discovered of the three formed blood elements. Several scientists have been interested in them, recognizing them as cells other than leukocytes and erythrocytes. Its job in hemost [...] 60 512 |
Machine Perfusion of Donor Hearts – The Recovery and Transplantation of Previously Unrecoverable Heartsby
Sanjay Dutta
,
Jeanette E. Villanueva
,
Yashutosh Joshi
,
Ling Gao
,
Paul Jansz
and
Peter S. Macdonald
Abstract Heart transplantation remains the gold standard treatment for end-stage heart failure. With an increasing population and improving medical therapy there is an increasing number of patients who would benefit from heart transplantation but are unable to receive one due to a shortage of sui [...] 69 653 |
BK Virus-Associated Nephropathy in Adult Patients Post Kidney Transplantation: What Progress in 30 Years of History?Abstract Completely unknown before the 90s and exceptional up to the 2000s, BK virus nephropathy (BKvN), usually known as polyomavirus-associated nephropathy, has emerged as a significant and severe viral complication in kidney transplantation (KT). More than twenty years after Gardner's discovery of BKv in [...] 107 832 |
Impact of Intravenous Immunoglobulin Replacement Therapy on Hypogammaglobulinemia and Infection in Lung Transplant RecipientsAbstract Secondary hypogammaglobulinemia (HGG) from immunosuppression therapy in lung transplant recipients has been associated with increased mortality, morbidity and higher risk of infection. Intravenous immunoglobulin (IVIG) for the treatment of HGG post-lung transplant is not well studied wit [...] 117 962 |
Detection of Activated Pepsin in Bronchoalveolar Lavage and Acute Cellular Rejection in Lung Transplant RecipientsAbstract Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii)&l [...] 159 1107 |
Management of Calcareous Corneal Degeneration from Medication Washout to Corneal Transplantation. Case Series and Review of the LiteratureAbstract Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the man [...] 135 1172 |
Circulating lncRNAs HOTTIP and HOTAIR as Potential Biomarkers in Crigler-Najjar Syndrome: A Preliminary Report from Shiraz Liver Transplant Research Centerby
Nasrin Motazedian
,
Masoud Mokhtari
,
Negar Azarpira
,
Kimia Falamarzi
,
Mohsen Mohammadi
,
Seyed Mohsen Dehghani
,
Sarina Pourjafar
,
Maryam Ataollahi
,
Elaheh Esfandiari
,
Mahdokht Hossein-Aghdaie
,
Seyed Ali Malekhosseini
,
Tayebeh Kazemi
and
Mahintaj Dara
Abstract Crigler-Najjar syndrome (CNS) is a rare autosomal recessive disorder characterized by impaired bilirubin metabolism, leading to neurotoxic unconjugated bilirubin accumulation. Liver transplantation remains the only effective treatment, highlighting the need for novel diagnostic and thera [...] 159 1243 |
Is Donation after Circulatory Determination of Death in Japan Uncontrolled or Controlled?Abstract Using donation after circulatory determination of death (DCD) donors has been shown to be a potential means of increasing the number of donors for organ transplantation. The purpose of this study was to examine the published practice of DCD in Japan to properly define their practice as controlled or [...] 176 1413 |
Advances in Managing Infections in Lung Transplantation: A Reviewby
Shourjo Chakravorty
and
Ashka Patel
Abstract Transplanted lung allografts are particularly susceptible to infection among SOT due to the constant exposure to the environment, aggressive immunosuppressive strategies, and impaired clearance mechanisms after denervation of the transplanted lung. Though prophylactic antimicrobial, anti [...] 163 1410 |
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