OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.1 weeks; Submission to Acceptance: 17.0 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

Current Issue: 2024  Archive: 2023 2022 2021 2020 2019 2018 2017

Special Issue

Advances in Mitochondrial Genome Research

Submission Deadline: September 15, 2020 (Open) Submit Now

Guest Editor

Frederic J. Brenner, PhD

Professor, Department of Biology, Grove City College, 100 Campus Drive, Grove City, PA 16127, USA

Website | E-Mail

Research Interests: General Ecology; wildlife and fishery management; wildlife genetics; wildlife diseases; forestry

About this topic

Mitochondria are organelles of eukaryotic cells and have their own genomes. Their genomes are collectively called the mitochondrial genome. The participation of and control by nuclear genes are essential for both mitochondrial structure and its activities. Further, nuclear genes play a dominant role in the genetic control of the whole organism. Mitochondrial DNA (mtDNA) can be used for molecular phylogenetic studies. The genes in the mitochondrial genome are closely related to the oxidative phosphorylation of mitochondria and are, therefore, related to the energy supply in the cell. In recent years, it has been found that some neuromuscular degenerative diseases, Parkinson's disease, Alzheimer's disease, mitochondrial encephalomyopathy, maternally inherited diabetes, and deafness are related to mitochondrial genes. Some studies have also pointed out that aging may be related to the accumulation of mtDNA damage. In addition, since the mitochondrial gene belongs to the maternal inheritance, the analysis of the prenatal mitochondrial genome of the mother is of great significance for the birth of healthy babies.

The human mitochondrial genome is a double-stranded circular DNA molecule, consisting of 16,569 nucleotides. mtDNA variants have been linked to various diseases and important biological processes, such as cancer, aging, etc. Mitochondrial research is on the rise across multiple fields in the medical sciences. Especially with the rise of high throughput sequencing, researchers now can examine the mitochondria genome in unprecedented detail. In this Special Issue, we will compile the articles that reflect the information on current research on mitochondrial genomes. We welcome original research reports, review articles, communications, perspectives, etc., in all areas pertinent to this topic.

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (genetics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!

Newsletter

TOP