Understanding the Regulation of Transcription in Mental Illness
Abstract
(ISSN 2577-5790)
OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.1 weeks; Submission to Acceptance: 17.0 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Special Issue
Chromatin Remodeling
Submission Deadline: March 31, 2021 (Closed) Submit Now
Guest Editor
Jean-Baptiste Vannier, PhD
Telomere Replication and Stability Group Head, MRC London Institute of Medical Sciences (LMS), London, United Kingdom
Honorary Senior Lecturer, Faculty of Medicine, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom
Research Interests: Cell Biology; Cancer Research; Molecular Biology; Genome Stability; Telomere; DNA Replication; DNA Damage Response; Homologous Recombination; Cell Culture; Chromosome Breakage; Recombination.
Co-Editor
Rosa Maria Porreca, PhD
Research Scientist, Telomere Replication and Stability Group, MRC London Institute of Medical Sciences (LMS), London, United Kingdom
Faculty of Medicine, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom
Research Interests: Telomere; DNA Replication; Cell Biology; Chromosome Breakage; Recombination.
About This Topic
Eukaryotic chromatin is a highly organized DNA-protein complex tightly packaged into a compact structure inside the nucleus. The basic unit of this structure is called nucleosome and consists of a histone octamer (H2A, H2B, H3, H4) wrapped around by 147 bp of DNA and a histone linker H1. Chromatin a is very dynamic structure and a wide variety of protein complexes are involved in different mechanisms to remodel chromatin by altering position, occupancy or composition of a nucleosome. Given the tightly compacted genome, chromatin remodeling can switch on and off DNA accessibility as needed, therefore regulating several biological processes like transcription, DNA replication, repair and recombination, chromosome assembly, cell-cycle and segregation, embryonic development and other processes. Hence, any defects in chromatin remodelers can lead to a broad spectrum of diseases including developmental disorders and cancer.
In this special issue we invite you to submit the latest research progress, innovative methodologies or therapeutics interventions, in all areas pertinent to the chromatin remodeling topic. Original research papers, reviews, editorial, short communications, case reports and perspectives are all welcome for submission.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (genetics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
Publication
Understanding the Regulation of Transcription in Mental IllnessAbstract Advances in clinical psychiatry have been less than hoped for relative to the achievements in neuroscience. However, developments in neuromodulation and psychedelic therapy are promising. The efficacy of such treatments and canonical pharmacotherapies benefit from genetics and personalized medicine. Moreover, recent studies on the perturbation [...] |
2023 | ||
CiteScore | SJR | SNIP |
0.4 | 0.160 | 0.093 |
TOP