OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes research articles, reviews, communications and technical notes, etc. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
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Rapid publication: manuscripts are undertaken in 15.0 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).
Aging, Dementia and Age-related Comorbidities
Submission Deadline: October 31, 2022 (Open) Submit Now
Shin Murakami, PhD, FGSA, Professor
Department of Basic Sciences, College of Osteopathic Medicine, Touro University California, USA
Research Interests: aging; stress resistance; cognitive functions; Alzheimer’s disease; genetics; geriatrics; genetics and epigenetics of aging; role of metabolism genes in AMI (age-related memory impairment) and dementia; midlife crisis theory of aging
About this Topic
The scope of this special issue includes age-related changes, diseases and comorbidities that links to aging. Recent advancement of genetic and epigenetic studies opens a new door to the understanding of aging. Human genome project has shifted from the public project to personal genome projects that produce results readily available to the consumer. This trend of direct-to-consumer (DTC) is expected to revolutionize the whole picture of medicine. Studies of aging have been shifting from the understanding the mechanisms of single-gene mutations to that of genetic and epigenetic variations. The variations presumably result in the diversity of longevity at individual levels. The genetic and epigenetic implications must be validated that will be a significant limit for human studies. The model systems are advantageous for functional analysis. The scope of this special issue includes but not limited to the studies of model systems, readily applicable implications to each individual, such as genetic variations and risk assessments, nutritional and pharmacological implications, and age-related diseases and damage (e.g., oxidative stress and age-related glycations) and theories. I hope to collect a heritable knowledge toward the transition from young to old, which is explained by the middle-life crisis theory of aging.
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