OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes research articles, reviews, communications and technical notes, etc. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
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Rapid publication: manuscripts are undertaken in 15.0 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).
Development and Implementation of Robust Assays for Target-based High Throughput Screens
Submission Deadline: December 31, 2021 (Open) Submit Now
Nava Krishnan, PhD
AbbVie Inc., United States.
Research Interests: enzymology; signal transduction; targeted therapy
about this Topic
High throughput screening is one of the dominant and widely utilized method to identify novel pharmacological agents. With a carefully designed assay and a good collection of compounds, novel chemical classes of ligands for a target can be identified. This approach can be used to identify active site directed and allosteric modulators of targets. In this special edition, designing robust screening assays using novel technologies and the success of using such approaches will be discussed with case studies. In addition, compound library, diversity, and its significance in identifying quality hits will be covered. Lastly, assay interference is a common problem faced by HTS campaigns, novel technologies used to overcome this will be discussed.
Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. Guidelines for authors and other relevant information for submission of manuscripts are available on the Instructions for Authors page. OBM Genetics is an international peer-reviewed Open Access monthly journal published by LIDSEN. Please visit the Instructions for Authors page before submitting a manuscript.
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