Effects of Enriched Thematic Multi-Sensory Stimulation on BPSD in A Beach Room: A Pilot Study among Nursing-Home Residents with Dementia

Renate Verkaik ^{1, *}, Iris van der Heide ¹, Eugenie van Eerden ², Peter Spreeuwenberg ¹, Erik Scherder ³, Anneke L. Francke ^{1, 4, 5}

1. NIVEL, Netherlands Institute for Health Services Research, P.O. Box 1568, 3500 BN, Utrecht, The Netherlands

2. Amaris Zorggroep, Werkdroger 1, 1251 CM, Laren, The Netherlands

3. Department of Clinical Neuropsychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands

4. Department of Public and Occupational Health, Amsterdam Public Health research institute Van der Boechorstsstraat 7, 1081 BT, Amsterdam, The Netherlands

5. Expertise Center for Palliative Care VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

* Correspondence: Renate Verkaik

Academic Editor: Ladislav Volicer

Special Issue: Behavioral Symptoms of Dementia

Received: April 02, 2019 | Accepted: November 26, 2019 | Published: December 11, 2019

OBM Geriatrics 2019, Volume 3, Issue 4, doi:10.21926/obm.geriatr.1904092

Recommended citation: Verkaik R, van der Heide I, van Eerden E, Spreeuwenberg P, Scherder E, Francke AL. Effects of Enriched Thematic Multi-Sensory Stimulation on BPSD in A Beach Room: A Pilot Study among Nursing-Home Residents with Dementia. OBM Geriatrics 2019; 3(4): 092; doi:10.21926/obm.geriatr.1904092.

© 2019 by the authors. This is an open access article distributed under the conditions of the Creative Commons by Attribution License, which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is correctly cited.

1. Introduction

Psychological and behavioral disturbances, such as depressive feelings, agitation, apathy, and sleep–wake disturbances, represent a severe burden for several people suffering from dementia as well as their caregivers [1,2]. Scientific studies have demonstrated that pharmacological interventions are often not much effective in reducing these disturbances, and may instead result in negative side effects, such as the increased risk of falling or accelerated cognitive decline [3]. Strong hopes have, therefore, been attached to psychosocial interventions [4].

Studies conducted on the effectiveness of psychosocial interventions have indicated that sensory stimulation represents a promising approach to reduce psychological and behavioral disturbances in people with dementia [5,6,7,8,9]. Multi-sensory stimulation involves the simultaneous stimulation of multiple senses, through the use of, for example, a variety of lights, gentle stimulating music, aromas, and tactile objects [10]. Traditionally, multi-sensory stimulation is offered in a multi-sensory room, also referred to as Snoezelen room. In this room, an array of equipment is installed, which offers multiple stimulations (i.e., aroma steamers, music, etc.) involving several sensory channels [11].

Limited evidence is available for the effectiveness of multi-sensory stimulation on behavioral and psychological disturbances in people with dementia. Recently, Larusso et al. [8] reported a systematic review of the impact of multi-sensory environments on the behavioral and psychological symptoms of dementia (BPSD), which included twelve relevant studies. These studies were mostly those which investigated and compared one-to-one interventions within a multi-sensory-room with other one-to-one activities, such as playing cards, quizzes, or watching photographs. The authors concluded that while multi-sensory stimulation was effective in reducing BPSD on a short-term basis (during or immediately after the intervention), it did not exhibit higher effectiveness compared to the other one-to-one activities. In a recent study that compared the effects of individual multi-sensory stimulation within a Snoezelen room with individualized music sessions on elderly people with severe dementia, Sánchez et al. [9] suggested that multi-sensory stimulation and music exerted comparable effects on the measures of agitation and mood after 16 weeks of intervention, while the multisensory stimulation in a Snoezelen room presented better effects on the measures of anxiety and dementia severity in comparison to the music intervention. On the basis of their review, Larusso et al. [8] provided a few recommendations for future research and interventions in this area. First, they advised conducting further research on the role of participants’ sensory preferences on the effectiveness of multi-sensory stimulation. Second, they advised to develop interactions that did not necessarily involve staff, such as those between different groups of patients, patients and volunteers, or patients and their family members, as these types of (group) interventions are more congruent with staff-to-patient ratios within the assisted living situations.

A relatively novel approach, partly based on multi-sensory stimulation and preferences of the patients, is the thematic multi-sensory stimulation. Thematic multi-sensory stimulation involves the simultaneous stimulation of multiple senses through the use of stimuli that are related to positive themes that could possibly arouse positive feelings and memories in patients. The assumed working mechanisms underlying the effect of thematic multi-sensory stimulation on psychological and behavioral symptoms are as follows: The development of behavioral problems in people with dementia has been associated with a reduction in positive experiences and in brain activity, which might be caused directly (brain damage) or indirectly (psychosocial aspects) by the dementia. Preferred stimuli activate the memories of positive events that happened earlier in the lives of patients with dementia [12]. Since positive memories are preserved better than the neutral memories, and are, therefore, activated relatively easily, and because the activation of positive memories generates positive experiences, multi-sensory stimulation with preferred stimuli is expected to provide higher effectiveness in reducing the behavioral problems compared to the multi-sensory stimulation with neutral stimuli. Neurobiological studies further raise the expectation that multi-sensory stimulation exerts a positive influence on both behavioral problems and sleep-wake cycles in people with dementia. A few researchers assume that sleep-wake cycles could even play an intermediary role in the reduction of behavioral problems [7].

Thematic multi-sensory stimulation is, therefore, based on the following assumptions: a) stimuli are able to reinforce each other if they are thematically related; b) arousing positive memories exerts a positive effect on the behavior of people with dementia [13].

The study conducted by Goto and colleagues suggested that thematic multi-sensory stimulation might indeed lead to improvements in psychological and behavioral outcomes [14,15]. In their study, a Japanese garden room was compared with stimuli in a Snoezelen room. The subjects who visited the Japanese garden room exhibited reduced stress levels and positive behavioral changes, which were observed to be either absent or present to a very limited extent in the subjects who visited the Snoezelen room [14]. One of the characteristics of Japanese gardens is that they are designed to occupy a small space and may be viewed from the living area. The Japanese garden in the study conducted by Goto et al. was a temporary indoor Japanese garden within a nursing home. The design of the garden represented a typical tea garden comprising stones (visual), plants (visual and olfactory), a water basin (sound and olfactory), a stone lantern (light), and a bamboo fence (visual). The fragrance of chrysanthemum was noticeable in the room [14,15]. Goto et al. [15] explained the positive effects of the Japanese garden through a combination of factors: (1) the landscape of the Japanese garden induced the viewers to scan a wide area, increased their alertness, and decreased their physiological stress, compared to viewing a control unstructured garden space; (2) several subjects stated having pleasant memory associations with nature; (3) the fragrance of chrysanthemum from the garden lowered the average heart rate.

The objective of the present study was to further explore the effects of enriched thematic multi-sensory group stimulation on the behavioral and psychological symptoms (depression, agitation, apathy, and sleep disturbances) in people with dementia. It was hypothesized that when a greater number of senses are stimulated simultaneously around a positive theme (enriched thematic multi-sensory stimulation), a greater positive impact on the behavioral and psychological symptoms occurs. The experimental thematic multi-sensory condition comprised a room in which a beach environment was simulated. The ‘beach’ theme was selected because it offers the opportunity to stimulate various senses, and is, in Dutch people, often associated with positive memories. The Beach Room stimulated senses through tactile, visual, auditory, olfactory, and taste stimuli. The control condition was a social café type condition. The following research questions were formulated:

1) Does enriched thematic multi-sensory group stimulation in a beach environment reduce the symptoms of depression, agitation, and apathy among the nursing home residents with dementia in comparison to the non-enriched stimulation in a social café type condition?

2) Does enriched thematic multi-sensory stimulation in a beach environment improve sleep-wake cycles, observed behavior, and mood among the nursing-home residents with dementia in comparison to a non-enriched stimulation in a social café type condition?

2. Materials and Methods

2.1 Study Design

The present study was designed as a pilot randomized controlled trial (RCT) conducted with repeated measurements and the following two conditions: (1) enriched multi-sensory group stimulation in a thematic Beach Room; (2) visiting the nursing-home’s standard Grand Café room, without the enriched multi-sensory stimulation.

2.2 Population

The present study was conducted in a nursing home in the Netherlands in two comparable wards for people with dementia. All the residents with dementia who had been residing in one of the two wards for at least one month were eligible for inclusion in the present study. A total of 40 residents (20 in the Beach Room group and 20 in the Grand Café group) were considered suitable for the pilot character of the study.

2.3 Experimental and Control Conditions

The experimental ‘Beach Room’ condition comprised a room in which a beach environment was simulated. The Beach Room stimulated the senses by including the following: sand, heat, and a breeze (tactile); sunlight and beach scenery (visual); beach and sea sounds (auditory); the smell of the sea (olfactory); and non-alcoholic drinks (taste). Sunlight was simulated by using the Suntech Trippel Lamp [luminous intensity: 12,000–25,000 lux; luminous spectrum: 315 nm–2000 nm; sunlight power/m²: 400–500 W/m²] (www.suntechgroup.se). Groups of three to five residents were allowed to sit together in the condition, along with a nurse or occupational therapist. The environment encouraged these residents to interact with each other (e.g., to talk regarding the beach and the sea sounds or to throw a beach ball). These thematic interactions were also stimulated and supported by the nurse/occupational therapist present with the group.

There is a hypothesis that stimuli that are gathered around a positive theme exert a greater impact than the stimuli that are not, and there have been indications that light, having conversations, being with others, and having something to drink could in themselves exert effects on the psychological and behavioral problems and the sleep-wake disturbances. Therefore, in the present study, the afore-stated effects were controlled by allowing a neutral availability of these effects in the control condition. The control condition entailed visits to the nursing home’s standard Grand Café room. The environment was referred to as the ‘Grand Café’ because the room looked similar to a normal café, where the residents were offered drinks (non-alcoholic) and were allowed to sit together around a table rather than alone. The room contained common items of old-fashioned furniture and attributes (e.g., lamps and a clock) as well as the Suntech Trippel Lamp (identical to the lamp placed in the Beach Room). It was decided to include the Suntech Trippel Lamp in both the conditions because, as reported by previous studies, the light from this lamp is itself expected to exert a positive impact on psychological and behavioral disturbances [16,17,18]. If the conversations did not evolve naturally among the residents in the Grand Café, a nurse/occupational therapist maintained the continuity of the conversation, which could be regarding any topic.

2.4 Procedure

The present study was conducted in the Dutch nursing home Vreugdehof in Amsterdam. Two nursing-home physicians attached to the two psychogeriatric wards participating in the study screened all the residents for eligibility. The residents were eligible if they: (1) had received a diagnosis of dementia, (2) had no comorbid psychiatric disorder, (3) were physically able to visit the Beach Room or the Grand Café environment, and (4) had not visited the Beach Room prior to the study. The legal guardians of each eligible resident were asked for their informed consent. All the residents for whom informed consent was obtained were assigned randomly to the Beach Room condition or the Grand Café condition. Randomization was conducted by the researcher (EvE) by writing the names of the eligible residents on a paper, folding the papers and putting them in a vase, and drawing papers from the vase one by one. First, the names of the residents selected for the experimental condition were drawn, followed by the names of those for the control condition. Randomization was conducted once per ward and per round. The residents assigned to one of the two conditions participated in the present study three times a week for 30 min for a period of 12 weeks. This intensity and duration were selected because previous studies had demonstrated that the effects of MSS could be expected after six weeks of using this intensity [19]. Additionally, this intensity would provide an insight into the follow-up effects at twelve weeks. The participating residents always visited the Beach Room or the Grand Café at the same time of the day and with a permanent group of three to five people from their own ward that was accompanied by a nurse or an occupational therapist. This cycle of 12 weeks was repeated three times within a period of one year. There were two participating groups in each cycle and for each condition. In this way, a total of six groups were included in the experimental condition and six groups were included in the control condition, which corresponded to 20 residents per condition. The residents were always asked if they wished to visit the Beach Room or the Grand café. At certain times, they would not wish to go or did not feel well enough for the visit, in which case, they were not forced to go. In both conditions, there was one person who did not wish to go at all. In each cycle, there were three measurement time-points for the assessments of depression, agitation, and apathy:

Pre-test: just prior to the beginning of the intervention;

Post-test: six weeks after the commencement of the intervention;

Follow-up: 12 weeks after the commencement of the intervention.

In addition, measurements of residents’ sleep-wake cycles were noted, and the observations of their behavior and mood were recorded for five weekdays during the first, sixth, and twelfth weeks. A repeated measures design with pre-test, post-test, and follow-up measures was used, to enable an insight into the interim results.

2.5 Measurements

2.5.1 Socio-Demographic Characteristics and Preferences

The following characteristics of the participating residents were assessed using a questionnaire that was completed by the contact nurses at the time of inclusion in the study: age, sex, marital status (married, widow/widower, divorced, unmarried, and other), having children (yes/no), and duration of institutionalization (<3 months, 3 months–1 year, 1–3 years, and >3 years). In addition, preferences for beaches (yes/no) and Grand Cafés (yes/no) were assessed via the legal guardians of the residents after the allocation of the residents to one of the two conditions. Most of the residents with dementia present in the Dutch psychogeriatric nursing home wards suffer from moderate dementia (Global Deterioration Scale: stage 5) or moderately severe dementia (Global Deterioration Scale: stage 6) ([20]. If the residents were in the severe dementia phase (Global Deterioration Scale: stage 7) and were unable to move out of bed anymore, they were considered ineligible for participation in the present study. Since the differences among the Global Deterioration Scale stages of the residents were assumed to be minimal (stage 5 moderate dementia or stage 6moderately severe dementia) in both the experimental conditions, this was not investigated any further. Additionally, the type of dementia is mostly unknown and could, therefore, not be used in the analyses.

2.5.2 Primary Outcome Measures

The primary outcome measures were:

- Depression, measured using the MDS-Depression Rating Scale (DRS), with scores ranging from 0 to 14. A score of ≥3 indicated that a person was at an increased risk of being depressed [21]. The internal consistency of the DRS has been established at 0.71 (Cronbach’s α), while the sensitivity of this scale against a formal diagnosis of depression was 91%. The scale was developed specifically for the assessment of depression in the frail nursing home population on the basis of Certified Nursing Assistants observations [21]. Cornell Scale for Depression in Dementia (Dutch version) was also employed. A score of ≥8 in this scale indicated minor depression, while a score of ≥12 indicated moderate-to-severe depression [22]. The Cornell scale has a high inter-rater reliability (weighted Kappa = 0.67) and internal consistency (Cronbach’s α = 0.84) and was developed specifically for the assessment of depression in the people with dementia [22]. 

- Agitation, assessed using the Cohen-Mansfield Agitation Inventory, with scores ranging from 29 to 203. A score of ≥44 indicated agitation (CMAI) [23,24]. The reliability of the inventory was investigated through test-retest, Cronbach’s alpha, and split-half methods, which were determined to be 0.99, 0.92, and 0.82, respectively. The validity of the questionnaire was investigated through convergent validity, inter-rater agreement across items, and exploratory factor analysis. The results from the factor analysis of the CMAI using varimax rotation method yielded 4 factors labeled as Aggressive Behaviors, Non-Aggressive Behaviors, Verbal Aggression, and Hiding Behaviors, which explained 73% of the total variance. Convergent validity was confirmed by computing a correlation coefficient between the subscales together and with the total scale, which was significant between 0.43 and 0.90 (p < 0.01) [25].

- Apathy, measured using the Apathy Evaluation Scale, with scores ranging from 10 to 40. A score of ≥30 indicated apathy (AES) [26]. The internal consistency was determined to be excellent. In regard to congruent validity, the AES-10 and NPIa exhibited a moderate positive correlation, and when compared to a depression measure (CSDD), little or no positive correlation was observed, demonstrating satisfactory discriminant validity [27].

All four scales were previously validated in nursing-home residents with dementia. The scales were completed by the contact nurses of the residents.

2.5.3 Secondary Outcome Measures

The secondary outcome measures were as follows:

- Sleep-wake cycles, assessed using Actiwatch activity monitor (CamNtech Ltd., Cambridge, UK). Actiwatch uses an accelerometer to monitor the occurrence and the degree of movement-induced accelerations. It is worn around the wrist. It provides a feasible, non-invasive technique for studying sleep-wake cycles in institutionalized people with dementia, and is sensitive to treatment effects [16,28]. Actiwatches were worn for five days a week, 24 h each day, during the three measurement periods. The watches were held around the wrist by a bracelet that could be removed by cutting it through. When the participants did not wish to wear the Actiwatch any longer, the watch was removed. The Actiwatch data was then used to obtain information regarding the four aspects of sleep-wake cycle: (1) total mean activity across the days; (2) sleep efficiency on a scale (the time a person spends asleep in proportion to the total time spent in bed), ranging from 0% to 100%; (3) average sleep time across the days; and (4) sleep per night expressed as mean percentage per day. 

- Behavior of the residents, measured using the observation scale INTERACT. This observation scale has been designed specifically to measure the effects of multi-sensory stimulation on: speech (5 items; score 0–25); contact (4 items; score 0–20); reaction (4 items; score 0–20); stimulation (1 item; score 0–5); activities (4 items; score 0–20); and mood (4 items; score 0–20) [29]. A study conducted on the effects of Snoezelen integration in 24-h dementia care by Van Weert et al. [30] demonstrated inter-rater reliability of 0.83 (range: 0.68–0.99) for INTERACT.

- Mood of the residents, assessed using the INTERACT mood subscale and the observation scale FACE. The instrument FACE has been previously proved to be reliable in a severely demented and institutionalized population [31]. FACE comprises three face diagrams with different mouth shapes. Mood is rated as ☺ if smile predominates in the resident,