02 - LIDSEN Publishing Inc.丨The Open Access Publisher

Volume 5,Issue 2

Open Access Research Article

The PBAR Protocol: Antipsychotic Medication Reduction in the Nursing Home

Melodee Harris ,

Priya Mendiratta ,

Gohar Azhar ,

Ruofei Du and

Jing Jin

Received: 24 November 2020; Published: 15 June 2021; doi: 10.21926/obm.geriatr.2102172

Abstract

Neuropsychiatric symptoms (NPS) occur in almost all persons living with dementia. Antipsychotic medications are often prescribed inappropriately for persons living with dementia who experience NPS. Adverse side effects of antipsychotic medications include falls, sedation, cognitive dysfunction, prolonged QTc interval, extrapyramidal side effects, cerebrovascular events, metabolic changes, infection, and mortality. The purpose of this descriptive quality improvement project was to tes [...]

Open Access Research Article

Stenting of the esophagus in the course of the malignant dysphagia in elderly patients

Janusz Włodarczyk and

Alicja Włodarczyk

Received: 26 October 2020; Published: 07 June 2021; doi: 10.21926/obm.geriatr.2102171

Abstract

Esophageal cancer is a disease with difficult clinical management, and palliative therapy is the only predominant treatment. This retrospective study analyses the results of clinical management of elderly patients (>75 years of age) who were treated with esophageal stenting for malignant dysphagia due to primary esophageal cancer, including squamous cell carcinoma (SCC), esophageal adenocarcinoma (EAC), as well as secondary esophageal malignant strictures [...]

Open Access Review

Deep Brain Stimulation – Therapeutic Possibilities in Alzheimer's Disease

Ethan Fitzgerald ,

Dorian Kusyk and

Nestor D Tomycz

Received: 02 December 2020; Published: 30 April 2021; doi: 10.21926/obm.geriatr.2102170

Abstract

Alzheimer’s Disease (AD) is the leading cause of dementia worldwide, and represents a significant cause of cognitive decline, disability, and mortality. Ongoing clinical trials continue to investigate β-amyloid targeted therapy with unclear benefit, and we are currently limited to symptomatic treatment. Therefore, there is a salient need for the development of novel, potentially disease-modifying therapeutic strategies such as deep brain stimulation. This manuscript reviews Deep Brai [...]

Open Access Research Article

Promoting Quality of Life in Advanced Dementia Care: Reading Buddies Program as Service-learning

Scott A. Trudeau and

Megan E. Gately

Received: 08 February 2021; Published: 30 April 2021; doi: 10.21926/obm.geriatr.2102169

Abstract

The Reading Buddies Program was developed as a service-learning component of an Occupational Therapy Practice with Older Adults course as a collaboration between Tufts University and the VA Bedford Health Care System. The purpose of this service-learning program was to challenge graduate students’ implicit biases and improve communication skills when working with older adults with significant cognitive impairments. Through this collaboration, occupational therapy students provided in [...]

Open Access Research Article

Double-Blind, Placebo-Controlled, Randomized Clinical Trial Demonstrates Telomerase Activator TA-65 Decreases Immunosenescent CD8+CD28- T Cells in Humans

Gunasekaran Singaravelu ,

Calvin B Harley ,

Joseph M Raffaele ,

Pratheesh Sudhakaran Sudhakaran and

Anitha Suram

Received: 27 January 2021; Published: 29 April 2021; doi: 10.21926/obm.geriatr.2102168

Abstract

TA-65 is a small molecule telomerase activator extracted from Astragalus species. A previous observational study suggested that TA-65 decreased the number of immunosenescent cells in healthy subjects. Here we examined the impact of TA-65 in a much larger randomized, double-blind, and placebo-controlled study. This study aims to evaluate the effects of TA-65 on senescent CD8⁺CD28

Open Access Review

Admiral Nurse Case Management within Enhanced Health in Care Homes

Zena Aldridge and

Karen Harrison Dening

Received: 15 February 2021; Published: 21 April 2021; doi: 10.21926/obm.geriatr.2102167

Abstract

The United Kingdom’s (UK) older population is higher than the global average. Over the next 20 years, England will see an increase in the number of older people who have higher levels of dependency, dementia, and comorbidity many of whom may require 24-hour care. Currently It is estimated that 70% of residents in nursing and residential care homes either have dementia on admission or develop it whilst residing in the care home. The provision of high-quality care for this population is a challeng [...]

Open Access Review

The Role of Fatigue in the Aging Swallow: A Review

Danielle Brates ,

Michelle S. Troche and

Sonja M. Molfenter

Received: 29 October 2020; Published: 15 April 2021; doi: 10.21926/obm.geriatr.2102166

Abstract

Fatigue is a term commonly used to describe patient performance and/or subjective experience in the evaluation and management of swallowing disorders (known as dysphagia). There is an association between fatigue and aging, as well as fatigue and many dysphagia-causing diseases/disorders. Therefore, speech-language pathologists (SLPs) are justifiably aware of and concerned about the potential impact of fatigue on swallowing performance and mealtime behavior. However, there is minimal agreement on [...]

Open Access Research Article

Translation and Validation of “Brief Bedside Dysphagia Screening Test” in a Greek Sample of Neurological Patients

Sophia Demeneopoulou ,

Marianna Mantzorou ,

Petra Mandysova ,

Nikoletta Margari ,

Eleni Dokoutsidou ,

Aggeliki Tsiligianni ,

Chrysoula Tsiou and

Theodoula Adamakidou

Received: 09 October 2020; Published: 02 April 2021; doi: 10.21926/obm.geriatr.2102165

Abstract

Background. Dysphagia may be a threatening condition if not diagnosed and treated early. Healthcare professionals need simple, quick and reliable tools for their daily clinical practice to be able to evaluate it immediately. The purpose of the present study was the translation and validation of the tool Brief Bedside Dysphagia Screening Test-Revised (BBDST-R) in Greek language in a sample of patients with neurological disorders. Methods. A crosssectional study was conducted with a convenien [...]

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