OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period).
Older People, Health, Functionality and Physical Activity
Submission Deadline: March 31, 2023 (Open) Submit Now
Pedro Morouco, PhD, Associate professor
1: Department of Human Kinetics, Polytechnic Institute of Leiria, 2411 Leiria, Portugal
2: ciTechCare, Center for Innovative Care and Health Technology, 2410-541 Leiria, Portugal
Research Interests: Exercise and health; Sport sciences; Elderly; Osteoarthritis; Exercise physiology; Sports science
Pablo J. Marcos-Pardo, PhD
1: SPORT Research Group (CTS-1024), CERNEP Research Center, University of Almería, Almería, Spain
2: Department of Education, Faculty of Education Sciences, University of Almería, Almería, Spain
Research Interests: Older; Elderly; Physical activity; Sarcopenia; Fitness
Noelia González Gálvez, PhD
Universidad Católica de Murcia
Research Interests: Physical activity; Sport; Adolescents; Older; Systematic review; Endurance; Fitness; Cardiovascular; Sarcopenic
About This Topic
The aging process brings with it different changes that position the health of the elderly at a vulnerable point. These changes favor a sedentary lifestyle, increased body weight, decreased muscle mass, increased sarcopenia, osteoporosis, decreased functional capacity, increased frailty, among others, and consequently decreased quality of life in the elderly. Bearing in mind that the main cause of death is cardiovascular accidents and the main cause of morbidity is frailty, the approach to the effects and benefits of practicing physical activity on cardiovascular health and frailty is especially relevant. This Special Issue entitled "Older People, Health, Functionality and Physical Activity" has the objective of covering research on the area of cardiovascular health and fragility in adults and elder and the effect of physical activity.
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