(ISSN 2638-1311)
OBM Geriatrics is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Publication Speed (median values for papers published in 2024): Submission to First Decision: 6.3 weeks; Submission to Acceptance: 11.4 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Special Issue
Age-related Changes in Skin in Health and Disease
Submission Deadline: May 31, 2026 (Open) Submit Now
Guest Editor
Frederick Silver, PhD
Professor, Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA
Research Interests: Extracellular matrix; biomaterials; biomechanics; mechanotransduction; medical devices; skin cancer; wound healing
About This Topic
Skin is a window to the health of the whole human body. It is influenced by both external (gravity) and internal forces (tension in Langer’s lines) and stresses that affect the force and energy balances that regulate both metabolism and the onset of skin diseases. While gravity and cellular mutations affect the healing of wounds and the onset of radiation-induced skin cancers, there are many other changes associated with aging. The complex pathways involved in mechanotransduction and skin component turnover make understanding skin aging more complicated. Changes in skin cosmetology, the genetic makeup of skin cells, biochemical component changes, and alterations in elastic and viscoelastic mechanical properties of skin are quite complex and are interrelated with disease development. This special issue focuses on assembling papers that summarize the latest information on changes that occur in skin aging. It is my hope that this issue will bring together information on the changes in genetic factors, chemical, and physical properties of skin that occur with age and how these changes affect wound healing, skin cancer, and the pathogenesis of diseases that affect the health of older individuals.
Keywords
Connective tissue diseases; skin aging; viscoelasticity; skin cancer; wound healing; aging; mechanical properties; mechanotransduction; collagen; proteoglycans; integrins; genetic mutations
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (geriatrics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
- Newsletter