OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 12 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period). 

Current Issue: 2022  Archive: 2021 2020 2019 2018 2017

Special Issue

Depression in Older Adults

Submission Deadline: April 30, 2022 (Open) Submit Now

Guest Editor

Associate Professor Ling Xu, PhD

School of Social Work, University of Texas at Arlington, Arlington, TX 76019, USA

Website | E-Mail

Research Interests: Family Gerontology; Intergenerational Relations; Dementia Caregiving; Cross Culture Research; Health Outcomes in Later Life; Physical and Psychological Well-Being of Older Population

About This Topic

Depression is a common problem among older adults, but clinical depression is not a normal part of aging. Late-life depression can have devastating consequences. Despite its prevalence, depression is under studied among older adults. This Special Issue entitled “Depression in the Elderly” aims at convening basic and clinical research to foster our understanding of the mechanism/pathways between determents and/or protective or risk factors and depression, the influences of depression on other health aspects, as well as interventions or services that help with prevention and decreasing of depression among older adults. Research/clinical notes, systematic review, research protocol, empirical research with cross-sectional and longitudinal data, as well as evaluation of intervention/program on late-life depression are all relevant and welcome by this special issue.

Keywords:

Late-life depression; Depressed older adults; Depressive symptoms; Major depressive disorder; Older adults

Publication

Open Access Original Research

The Role of General Medicine in the Evaluation of Frailty in the Elderly Population: Definition of a Standardized Instrument for the Correct Framing of Frailty and Comparison with Currently Existing Instruments for Stratification of Clinical Risk

Received: 08 September 2021;  Published: 04 March 2022;  doi: 10.21926/obm.geriatr.2201192

Abstract

Frailty is a chronic condition that increases the vulnerability to stressogenic factors and prevents the patient from returning to the preceding condition of homeostasis. This increases the risk of negative outcomes and progressively brings the patient toward disability, leading to higher use of healthcare resources. Clinical risk stratificati [...]
Open Access Original Research

Adjustment for Covariates of Major Depressive Episodes among Men and Women Aged 65 Years Old and Older

Received: 17 August 2021;  Published: 22 December 2021;  doi: 10.21926/obm.geriatr.2104185

Abstract

The current study aimed to examine if sex can significantly predict risk for lifetime major depressive episodes among adults aged 65 and older with and without adjustment for covariate variables of race, education, marital status, health, and poverty. Secondary data was obtained from the National Survey on Drug Use and Health public-use data [...]
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